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Biomedical subjects

M G Lind

Publications and source records attributed to M G Lind.

At least 37 records · Page 2Linked to original sources

Split-rib graft for reconstruction of the mandible.

Defects in the mandible after tumor surgery were reconstructed with split-rib grafts in 23 patients. Twenty of the patients were preoperatively irradiated with fractioned radiotherapy, ranging from 40 to 85 gray. Partial sequestration appeared in five patients. The ingrowth of the transplant was examined with technetium scintigraphy. Satisfactory cosmetic and functional results were achieved in the great majority of the patients. Split-rib grafting is recommended for reconstruction of the mandible as a safe procedure with little increased operation time and morbidity for the patient and good functional and cosmetic results.

Aged↗

Tonsillar hyperplasia in children. A cause of obstructive sleep apneas, CO2 retention, and retarded growth.

Tonsillar hyperplasia causing obstructive sleep apneas in children is a well-defined clinical entity with nocturnal CO2 retention, retarded growth, and impaired physical and psychological status. Pulmonary hypertension, cor pulmonale, and ultimately, death may develop in a small number of these children. This syndrome may also develop in children with only moderately enlarged tonsils in association with neuromuscular hypothonia or anatomical defects. Anamnesis will readily detect the children at risk. The syndrome is cured completely by tonsillectomy. The CO2 retention disappears and length and weight growths are accelerated after surgery.

Carbon Dioxide↗

Facial bone scintigraphy. VII. Diagnosis of malignant lesions in the mandible.

Fifty-four patients were examined clinically, radiographically and scintigraphically with respect to mandible bone involvement by oral carcinoma. Sixteen resected mandibular specimens were available for microscopic examination and the results were correlated to the clinical, scintigraphic and radiographic results. Clinical assessment overestimated and radiography underestimated oral carcinoma involvement of the mandible; scintigraphy was more accurate than was clinical assessment or radiography. Combination of clinical examination with both conventional radiography and bone scintigraphy is recommended for optimum diagnosis of mandible bone involvement by oral carcinoma.

Adult↗

Facial bone scintigraphy. VIII. Diagnosis of malignant lesions in the maxillary, ethomoidal and palatal bones.

The results from radiographic and scintigraphic examination of 28 patients with malignant tumors of the nasal, paranasal and palate regions, 23 patients with purulent maxillary sinuitis, and 15 control cases were compared. A combination of radiography and scintigraphy yielded the best information on the differentiation between an inflammatory condition and malignant tumor and the extent of malignant growth in adjacent bone.

Adult↗

99TcmO4 as an indicator for specialized cell function in organ cultures of the human submaxillary gland. A pilot study.

Salivary gland tissue was cultured in vitro and viable cells were present during 14 days. The specific glandular cell function was estimated from the capacity to accumulate 99TcmO4 from the culture medium. The morphology of the cultured specimens was examined by light and electron microscopy. Structural changes and loss of the 99TcmO4 accumulation capacity increased with increasing culture time in vitro. A correlation was observed between the loss of 99TcmO4 accumulation capacity and the disappearance of zymogen granules from the cultured cells. However, the causative link between these two phenomena requires further analysis.

Cell Nucleus↗

Facial bone scintigraphy. VI. Practical clinical use in inflammatory disorders of the maxillary sinus.

Facial bone scintigraphy with 99Tcm-DP was compared with radiographic examination of the maxillary sinuses in a clinical routine series of patients considered to have inflammatory disorders of the maxillary sinus. Scintigraphy correlated better to the presence of purulent inflammatory lesion than did radiography. Bone tissue reaction is almost mandatory for the diagnosis of purulent maxillary inflammatory disorder.

Adolescent↗

Tinnitus caused by bilateral shunts from the occipital arteries to the intracranial veins. A case report.

A patient with objective tinnitus and a pulse synchronous murmur over both left and right sides of the mastoid regions is described. Microphones placed over the mastoid regions recording "phonomastoidograms" clearly demonstrated the pulse synchronous tinnitus. Arteriovenous shunts from the occipital arteries to the sigmoid sinus were later demonstrated with angiograms. After bilateral surgical removal of the arteriovenous shunts the incapacitating tinnitus disappeared. The importance of thorough examination of pulse synchronous tinnitus is discussed.

Arteriovenous Fistula↗

Facial bone scintigraphy. V. Differentiation of purulent from non-purulent inflammation of the maxillary sinus.

In a series of 25 patients 20 had a maxillary sinus not containing air at radiography, in 11 due to purulent and in 9 to non-purulent inflammatory lesion. At scintigraphy a definitely abnormal, high uptake of 99TcmDP was found in 10 and a probably high accumulation in one of the 11 with purulent sinuitis. Of the 9 patients with non-purulent inflammation 5 had a definitely normal and 4 a probably normal uptake. Thus, a differentiation between purulent and non-purulent sinuitis would seem to be possible by means of facial bone scintigraphy.

Humans↗

Facial bone scintigraphy. III. Effects of radiation therapy.

The uptake of 99Tcm-DP in normal facial bones was not changed by irradiation of malignant tumors. The intensity of the pathologic uptake into regions with active parodontitis in a few patients increased during irradiation. The uptake of 99Tcm-DP in bone with neoplastic growth varied during the period of treatment, probably depending on the tumor reaction to irradiation.

Aged↗

Radiographic diagnosis of foreign bodies in the oesophagus.

In a group of patients suspected of harbouring a foreign body in the oesophagus, the diagnostic accuracy of radiographic examination is found to be high. Only 1 of 243 patients examined by radiography presented a false negative result.

Adolescent↗

Facial bone scintigraphy. II. Diagnostic potential in neoplastic and inflammatory lesions.

From a series of about 200 facial bone scintigraphies, 32 patients were selected to demonstrate the uptake of 99Tcm-diphosphonate in various inflammatory and neoplastic diseases in the sinuses and oral cavity. The method was found of value in separating patients with inflammatory involvement of the bone from those without, as well as in assessing possible bone involvement in malignant lesions.

Bone Neoplasms↗

Scintigraphy of human autologous rib transplants to a partially resected mandible.

The 99Tcm-DP accumulation in split ribs grafted to six cases of partially resected mandibles was examined by scintigraphy at different time intervals after operations and found to be higher than in normal facial bones. The accumulation was highest around one month after the grafting procedure, and later decreasing. Differences between bone chips, split ribs and unsplit ribs are described. Bone scintigraphy is assumed to be of value in following the metabolic state of bone grafts.

Adult↗

99Tcm-DP accumulation in rabbit skull bones after 60Co gamma irradiation.

Histology demonstrated new bone formation and bone destruction in rabbit mandibles irradiated with 20 Gy in a single exposure, but no abnormality following 10 Gy in a single exposure. Gamma camera examination of the 99Tcm-DP distribution could not demonstrate any abnormalities, and is concluded not to be effective in demonstrating early radiation injury to bone tissue. Radiation therapy is considered a negligible source of false positive findings in scintigraphy of the facial skeleton.

Animals↗