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Biomedical subjects

M Forest

Publications and source records attributed to M Forest.

At least 73 records · Page 4Linked to original sources
PubMed1987

[Epidermoid cysts and implants. Anatomo-pathologic findings].

A case is reported that is exceptional in more than one respect. The mandibular region was the site of development of three cysts: a radiculo-dental cyst, a coronodental cyst in appearance but which could have been an epidermoid cyst and a typical epidermoid cyst. Lingual nerve lesions are a rare, major complication of implantations. Dismounting of a stable implant is a very rare occurrence. Histopathology showed a bone integration process in contact with the major part of implant, an interposed fibrous band existing in certain sectors only.

Adult↗
PubMed1987

[A peculiar tumor. Adamantinoma of the long bones. Apropos of 7 consecutive cases followed up after resection].

Seven cases of tibial adamantinoma have been reviewed. All were treated by en bloc resection and followed for one to twenty years after operation. Of five patients followed for more than three years, three have had a good result after 3, 12 and 20 years of follow-up. One patient suffered a recurrence in the soft tissues seven years after resection and remained well after thirteen years follow-up. One patient required amputation two years after resection and died from a mediastinal tumour of undetermined nature sixteen years after amputation. The two failures occurred in patients seen secondarily following recurrence after initial curettage. The tibial shaft was reconstructed in three cases by massive allografts. One of these failed because of infection but was reconstructed using autografts; one had a late fracture which united spontaneously. The third, after sound union, had to be amputated for recurrence. Two smaller resections were treated successfully by tibial and iliac autografts. Two cases were treated by free vascularised fibular transplants which united, though one suffered a late fracture which united spontaneously. Curettage, which is almost always followed by recurrence, should be rejected in favour of extensive resection. Resection is successful when done primarily but poses severe problems in reconstruction and requires a prolonged period of treatment. The small numbers in this series do not allow a judgement to be made as to the superiority of one technique over another.

Adolescent↗
PubMed1986

Frequency and diagnostic value of the virus-like filamentous intranuclear inclusions in giant cell tumor of bone, not associated with Paget's disease. A study of 43 cases.

This paper deals with the paramyxovirus-like intranuclear inclusions observed in giant cells tumours of bone (GCTB). Twenty-one (49%) of 43 cases of GCTB (1977-1985), either fresh and/or cultured, show these ultrastructural inclusions. Fifty samples of various bone lesions in which giant cell lesions occurred, including aneurysmal cysts, hyperparathyroidism, osteoblastoma, human and rat osteopetrosis, GCT of tendon sheaths, and non skeletal granuloma were used as controls. These, together with 20 samples of normal bone (osteoclasts) did not contain intranuclear or intracytoplasmic viral inclusions.

Bone Neoplasms↗
PubMed1986

[Double mitral orifice. An anatomical case].

A double mitral orifice was discovered at autopsy in a 74 year old woman. Death resulted after several episodes of cardiac failure complicating mixed mitral and aortic valve disease. A vertical limbus bridged the mitral annulus separating it into two distinct right and left orifices, with oblique long axes aligned towards the lower part of the limbus perpendicular to each other from the left atrial view. After opening the left ventricle, both orifices were observed to have their own sets of chordae tendinae attached to normal papillary muscles: the right orifice to the posterior and the left to the anterior papillary muscle. The inferior end of the limbus was attached to a supplementary papillary muscle. Echocardiography and CT scanning were performed before dissection. This malformation results from symphysis of the mid parts of the two mitral leaflets during embryonic stages 15 and 16 (8-10 mm vertex-coccyx, 31st-33rd days).

Aged↗
PubMed1985

Multifocal nonosteogenic fibroma: report of a case with ultrastructural findings.

The case of a patient in whom multiple nonosteogenic fibromas developed is reported. This condition is very unusual and must be differentiated not only from the multiple lesions that occur in association with well-known entities but also from some occasionally multifocal bone tumors. The lesion is characterized by proliferations of spindle cells disposed in storiform patterns, with numerous scattered multinucleated giant cells. Ultrastructural study revealed that the basic cell of this lesion had fine structural features of both fibroblast and myofibroblast cells.

Adolescent↗
PubMed1985

[Hip surgery: local tissue reactions].

Present extent of total hip prostheses, protracted course of first operations lead to pathological studies on local tissue reactions, sign of the failure or of the damaging of the artificial hip. Another pathology, often as intricate, is observed after more conservative surgery: high femoral osteotomies, cup arthroplasties, femoral metallic prostheses. Failure of an high femoral osteotomy shows a running of osteoarthritic lesions the topography of which is always modified by the new orientation of the articular bearing segment. Osteosclerosis, osteoarthritic cysts may develop on a preexisting osteophytosis. Osteonecrosis or bone resorption are sometimes found. Anatomical results in case of a successful osteotomy are scarce. Fibrous layer eventually quoted as a guide to the development of fibrocartilage is more often associated with osteoclast mediated bone loss. Efficient bone remodelling is assumed only, today, by radiological proof. Failures of cup arthroplasties induce femoral bone or acetabular cartilage lesions which are different according to the surgical technic. Some are marked by cartilage destruction of the acetabula or by a cup dislodgement. Bone structure in those cases shows under the cup a good remodelling with a fibrous or fibrocartilaginous mantle originating from the bone marrow spaces and the capsular attachment. In other cases, the femoral head presents areas of superficial or total osteonecrosis, signs of intense osteoclastic activity, cleaving of the fibrous surface and eventually metallic debris or cement induced histiocytic granuloma. A fibrous layer may develop between the cup and the acetabula. Femoral metallic prostheses may damage in some years cartilage of the acetabula. Osteoarthritic bone remodelling is sometimes observed in close contact with the metallic collar. Lesions of capsular tissues are eventually represented by metallic debris or an histiocytic granuloma due to cement anchorage. Material received at the time of surgical revision on total hip arthroplasties concerns chiefly the newly formed capsular and synovial tissues. Their appearance is quite similar to the tissular layers found between prosthetic material and bone or cement. For the pathologist, main inquiries are the rule out of an infection, the extent and course of the macrophage or giant cell response, the nature of wear debris or of the products of corrosion and the histological factors contributing to the loosening of the prosthetic components. It should be stressed that any physiopathological schedule of an artificial hip failure is a topographical and dynamic problem only partly resolved by studying autopsy material.

Arthroplasty↗
PubMed1985

Chondrocalcinosis and rapid destruction of the hip.

The frequency and significance of articular chondrocalcinosis was studied in 86 cases of osteoarthritis (OA) with rapid destruction of the hip that underwent total arthroplasty. The occurrence of articular chondrocalcinosis was 3 times more frequent than in a matched control population without rheumatic complaints (32.5% vs 10.5%). In a matched group of control patients operated on for common OA of the hip, the frequency of articular chondrocalcinosis (18.6%) was higher than in the control patients but significantly lower than in the patients with rapid destruction of the hip. Fifty-five patients in each of the 3 groups were aged 70 years or more, and the frequency of articular chondrocalcinosis in those patients with rapid destruction of the hip rose to 45.4% compared to 13.7% for the control group (p less than 0.01) and 27.2% for the group with common OA of the hip (p less than 0.05).

Aged↗
PubMed1984

[Monoarthritis symptomatic of adjacent bone tumors. Study of 5 cases].

The authors present 5 cases of monoarthritis which revealed adjacent bone tumours: a bony metastasis, a fibrosarcoma and three bone lymphomas. In three cases, the synovial histology showed lesions of non-specific synovitis without neoplastic invasion. A review of the literature demonstrates the rarity of these mono- or oligo- arthrites adjacent to bone tumours and two types can be distinguished: neoplastic invasion of the synovium or reactive non-specific synovitis without invasion.

Adenocarcinoma↗
PubMed1983

[Fibrosarcoma of bone].

The authors have treated forty-five cases of fibrosarcoma of bone between 1949 and 1979. Tumours with chondrogenesis or osteogenesis to any extent have been excluded from the study. The conclusions are that fibrosarcoma represent 10 p. 100 of all bone tumours. Microscopy was difficult and in some cases it was not easy to determine both the fibroblastic origin and the presence of malignancy. Eight per cent of the tumours were primary and 20 p. 100 secondary. The global results indicated 40 p. 100 survival after five years. Twenty-four cases were treated by amputation of which twenty-two were followed up and fifteen were alive after five years. In nine cases, resection was performed. Recurrence occurred in five cases, three of which had to be amputated of which two survived. Two others were treated by irradiation without success. Ten cases were treated primarily by irradiation of which only three survived after heavy dosage. Proximally situated tumours had a very poor prognosis with no survival. The prognosis appeared to be better in those under forty years of age (55 p. 100 survival) than over forty years (11 p. 100 survival).

Adolescent↗