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Biomedical subjects

M F Nesterin

Publications and source records attributed to M F Nesterin.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[Methandrostenolone residues in the tissues and biological fluids of agricultural animals stimulated by the preparation].

Residual amounts of hormonal-active substances were isolated from the tissues of farm animals stimulated with metandrostenolone-3H. The process of isolation included extraction with a mixture of polar solvents, hydrolysis, adsorption and partition column chromatography, thin-layer and paper chromatography, with radio-isotope, fluorometric, spectrophotometric and densitometric methods employed for identification. Results subsequent to determination of residual amounts of the compound are reported.

Adipose Tissue↗
PubMedDate not supplied

[Effect of methandrostenolone on liver morphology and enzymatic activity].

The action of different doses and time of metandrostenolone administration on liver morphology and activity of the enzymes of blood serum, liver and pancreatic tissue was studied in experiments on male rats. It was established that metandrostenolone regardless of its dose and time of administration produces changes in enzymatic activity and in morphological characteristics, manifesting in hypertrophy of hepatocytes in modification of the cell size of the reticuloendothelium as well as in the magnitude and amount of nucleoli in the nucleus. The changes also involve impaired rhythmicity of RNA and glycogen synthesis by the liver.

Animals↗