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M F Carette

Publications and source records attributed to M F Carette.

At least 55 records · Page 3Linked to original sources
PubMed1993

[Thoracic x-ray computed tomography and unexpected diagnosis of pulmonary embolism].

The gold standard for the diagnosis of pulmonary embolism is still pulmonary angiography. Chest CT scan with injection of contrast medium can demonstrate a pulmonary embolism. In some cases, CT may discover a non suspected embolism. The aim of this retrospective study was to point out when an injection of contrast medium is necessary during CT scan of the chest to avoid to overlook and unsuspected pulmonary embolism. Ten cases of suspected pulmonary embolism on CT were retrospectively studied. Two cases were false positives. Our method did not allow to study false negatives. Out of the eight true positive cases, four were not suspected by the physician and in all cases, the exam record was not really clear. At the end of this study and referring to the literature, we conclude that CT scan of the chest can be performed with injection of contrast medium if a pulmonary embolism is one of the eventual diagnosis when an other suspected affection is an indication for CT.

Aged↗
PubMed1992

[Tumors of the mediastinal nerves. Diagnosis and possibilities of conservative surgery. Apropos of 2 cases].

Two new cases of tumour of nerves running in the mediastinum are reported; one was a schwannoma of the right phrenic nerve, the other a schwannoma of the vagus nerve. In both cases the diagnosis was suspected on the basis of computed tomography scans. Treatment consisted of nerve-sparing tumour enucleation. The result was incomplete in the first patient, with partial paralysis of the diaphragm, and complete in the second patient, with no disturbance of pharyngeal motility. The authors discuss the diagnosis of these tumours and the validity of nerve-sparing surgery.

Cranial Nerve Neoplasms↗
PubMed1991

[Severe pulmonary artery involvement of Takayasu arteritis. 3 cases and review of the literature].

Three cases of pulmonary arterial disease were identified out of a cohort of 75 cases of Takayasu's disease. In the first case, pulmonary hypertension considered to be idiopathic caused massive haemoptysis and the death of a 48 year old Spanish woman; autopsy revealed characteristic stenoses of the common carotid arteries. In the second case, haemoptysis led to pneumonectomy in a 23 year old West Indian woman with a diagnosis of agenesis of the right pulmonary artery. Disease of the supraaortic vessels occurred several months later and a retrospective diagnosis of Takayasu's disease of the pulmonary artery was made. In the third case, systematic pulmonary angiography in a 41 year old French woman referred for Takayasu's disease of the supraaortic arteries showed severe stenosis of the right pulmonary artery. She developed severe haemoptysis four years later which led to an attempted balloon angioplasty of the right pulmonary artery and embolisation of a branch of the right coronary artery thought to be the cause of the haemoptysis. This was complicated by posterior wall myocardial infarction but the haemoptysis did not recur thereafter. These three cases and a review of the literature show that the pulmonary lesions of Takayasu's disease occur mostly on the main right pulmonary artery but they may be more distal and involve the pulmonary arterioles. A coronaro-broncho-pulmonary collateral circulation may develop distal to the stenosed segments. The main complications are pulmonary hypertension and massive haemoptysis. Surgery is possible in cases of stenosis of the right main pulmonary artery. The potential role of endoluminal angioplasty is discussed.

Adult↗
PubMed1990

Increased lung epithelial permeability in HIV-infected patients with isolated cytotoxic T-lymphocytic alveolitis.

HIV-related lymphocytic alveolitis is common in HIV-seropositive patients without lung infection or tumor. In some of them a fraction of alveolar lymphocytes are HIV-specific cytotoxic T-lymphocytes (CTL) bearing the CD8 and D44 cell surface markers and capable of killing HIV-infected alveolar macrophages. In order to evaluate the in vivo effect of these CTL on lung function, we measured the pulmonary clearance of aerosolized 99mTc-diethylene triamine penta-acetate (DTPA-CI) on 24 occasions in 22 patients with lymphocytic alveolitis. DTPA-CI has been selected as a highly sensitive test to detect injury of the lung epithelium. In 13 of the patients, we found a high DTPA-CI of 4.56 +/- 2.54%.min-1 (mean +/- SD), suggesting an increase of the epithelial permeability. The lymphocytic alveolitis was then characterized by a high cellularity, a high proportion of lymphocytes (59 +/- 18%), mainly composed of CD8+D44+ T-lymphocytes (149 +/- 109 cells/mm3), which spontaneously exhibited a cytolytic activity against the autologous alveolar macrophages in a standard 51Cr release assay. In the remaining 11 patients, DTPA-CI was normal (less than 1.78%.min-1), lymphocytic alveolitis being characterized by a low number or an absence of CD8+D44+ alveolar lymphocytes (9 +/- 13 cells/mm3) with no significant cytolytic activity. In the whole group, a significant correlation (r = 0.74, p = 0.0004) was found between the DTPA-CI and the number of CD8+D44+ lymphocytes and their cytotoxic activity against alveolar macrophages. Altogether, these results suggest that an injury of the lung epithelium could result from a HIV-specific CTL-induced immunologic conflict.

Adult↗
PubMed1990

[Cavitary pneumocystis carinii pneumonia in AIDS: a new semiologic aspect. Apropos of 3 cases].

Three cases of AIDS patients hospitalized for Pneumocystis carinii (PNC.C) pneumonia are reported. These cases are of interest because of the unusual radiological semiology of these pneumocytoses, i.e., their partially or totally pitted nodules. In addition, 4 related facts merit attention: the occurrence of pneumocytosis in 1 patient under prophylactic aerosol pentamidine therapy: the rarity, unusual in AIDS, of PNC.C in the bronchoalveolar lavage fluid from 2 patients; the association of pitted nodules with mediastinal adenopathies due to PNC.C in 1 patient; and the favorable outcome in all cases.

Acquired Immunodeficiency Syndrome↗
PubMed1989

[Cardiac imaging using magnetic resonance].

Today, two types of cardiac imaging may be obtained in MRI. The spin-echo technique with ECG dependency permits to obtain multiple sections in all spatial planes; the morphology of the heart cavities may then be evaluated as well as the condition of the myocardium (thickness, signal, movements). The gradient-echo technique permits a quick imaging or cine-MRI. 16 to 32 images per cardiac cycle are obtained: therefore, analysis of the flows, turbulence and regurgitations. Early developments involve computer sciences: automatic analysis of the heart cavities (volume, stroke volume, etc.) and regurgitations in order to quantify them. Comparative trials show a good correlation with standard explorations. Late developments at 4-5 years: these are newly acquired techniques such as echo planar (spirals of Fourier's plane) permitting to obtain in one second, 8 stages of the heart cycle. This would then be a true and fast cardiac recording. The same techniques of computer analysis will permit to obtain precise measurements.

Coronary Circulation↗
PubMed1989

[A new case of necrotizing pneumocystosis in AIDS].

The authors report the case of an AIDS patient presenting with both Streptococcus pneumoniae pneumoniae and pneumocystosis. What was remarkable in that case was the appearance, in an otherwise favourable course, of a large excavation in the territory of the pneumonia. The responsibility of Pneumocystis carinii in this excavation is discussed.

Acquired Immunodeficiency Syndrome↗
PubMed1989

[Desmoid tumors of the mesentery in Gardner's syndrome. Value of x-ray computed tomography].

3 cases of desmoid tumours of the mesentery occurring as part of Gardner's syndrome are reported. In 2 cases, CAT scanning was carried out. We underline the value of this examination compared to other imaging methods. It allows the establishment of a diagnosis, investigation for complications, the operability to be assessed and is useful for monitoring patients. Its major value is in avoiding an unnecessary laparotomy, a factor certain to produce recurrence, in certain patients. Other alternative therapy may then be proposed.

Adult↗
PubMed1989

[Unusual thoracic localization of Castleman's tumor. Apropos of a case].

We report a case of angiolymphoid hyperplasia, or Castleman's pseudotumour, located in the chest and most unusually opposite an intercostal space. Pain led to the discovery of the tumour, the nature of which was discovered at surgery, and disappeared after surgical excision. No antigenic stimulus or local haemodynamic disturbance was found, which could have accounted for the very unusual intercostal site of the lesion.

Adult↗