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Biomedical subjects

M Englert

Publications and source records attributed to M Englert.

At least 37 records · Page 2Linked to original sources
PubMed1984

Sensitivity and specificity of pulsed Doppler echocardiography in detection of aortic and mitral regurgitation.

In order to assess the value of pulsed Doppler echocardiography in detection of valvular regurgitation, 63 patients were evaluated for aortic and/or mitral regurgitation using pulsed Doppler echocardiography and selective cineangiography. The Doppler study was considered as positive when a turbulent flow was detected below the aortic valve for aortic insufficiency and behind the mitral valve for mitral insufficiency on a graphic display (time interval histogram) when technically adequate and/or on an audiosignal. These results were compared with standard angiographic evaluation of the regurgitation: pulsed Doppler echocardiography had 94% sensitivity and the specificity rate was very high (87.5%) even for mild regurgitation. Thus, Doppler technique is highly specific and sensitive in detection of aortic and mitral regurgitation when both audiosignal and time-interval histogram are simultaneously performed.

Aortic Valve Insufficiency↗
PubMed1984

Right atrial thrombus leading to pulmonary embolism.

Cross sectional and M mode echocardiography detected a large right atrial mass in a 70 year old man five days after admission. Three weeks later he developed acute respiratory failure due to a pulmonary embolism. Necropsy showed that the atrial mass was a thrombus. Thus echocardiography should be performed in patients with pulmonary emboli to examine the right cardiac cavities. The need for emergency surgery could then be assessed.

Aged↗
PubMed1984

Hemodynamic effects of dobutamine in patients below and over 65 years, with left heart failure secondary to an acute myocardial infarction.

The cardiac response to sympathomimetic agents has been reported to be reduced in the elderly. We studied the hemodynamic effects of dobutamine in two groups of patients with acute myocardial infarction (AMI) and left heart failure: group A included 10 patients aged 65 years or less and group B 10 others older than 65. After a 1-hour infusion the increase in cardiac index was highly significant in both groups (27%, p less than 0.001 and 25%, p less than 0.001), and the decrease in pulmonary wedge pressure was greater in group A (42%, p less than 0.001 and 17%, p less than 0.02). The increase in double product was similar in both groups (14%, p less than 0.001 and 18%, p less than 0.005); nevertheless the 4 patients developing angina pectoris during dobutamine infusion were over 65 years. We conclude that dobutamine remains effective in the elderly with AMI and left heart failure but is less well tolerated.

Age Factors↗
PubMed1982

Evaluation of mitral stenosis by the study of the left ventricular diastolic phase.

The left ventricular relaxation period has been studied by digitized monodimensional echocardiography in 14 patients with symptomatic pure mitral stenosis and in 11 normal subjects. The maximal relaxation rate and the maximal circumferential relaxation rate differed significantly in both groups (p less than 0.001) with a marked reduction in the patients with mitral stenosis; it was, however, not possible to trace a significant correlation between mitral valve area and the indices of diastolic phase, excepted a slightly significant one for the mean relaxation rate (r = 0.7). In spite of the fact that these results show a delayed left ventricular filling in mitral stenosis, the correlation with the mitral valve area was poor and suggests that it is not satisfactory to estimate the left ventricular filling only by the variation of the ventricular transverse diameter, and that a more accurate evaluation of the mitral valve area should include, in addition to the measurement of the ventricular relaxation rate, at least an indirect estimation of the transmitral pressure gradient, for instance by Doppler echocardiography of the transmitral flow.

Diastole↗
PubMed1978

Evolution of intrathoracic airway mechanics during lung growth.

Elastic recoil pressure of the lungs (Pst(L)), maximum expiratory flow rates (MEF), critical transmural pressure of the collapsible flow-limiting segment (Ptm'), and S-segment conductance (Gs) have been determined in 40 healthy subjects, 7-18 yr old. Pst(L), measured at different lung volumes (fractional) from the expiratory quasi-static pressure-volume curves, increases progressively with age. MEF's, at different lung volumes, are closely related to total lung capacity (TLC); the ratios MEF/TLC, at all lung volumes, are independent of age. Ptm' is also independence of age and body height, most values lying between 0 and -15 cmH2O; this finding suggests that the locus and the behavior of the collapsible segment do not change during growth. Gs, in absolute value, increases with growth but, when adjusted for lung size, Gs decreases steadily with age and body height. These relations suggest that, from childhood to adolescence, the air spaces grow disproportionately more than the airway system.

Adolescent↗