Search PubMed⌕ Search

Biomedical subjects

M Endo

Publications and source records attributed to M Endo.

At least 739 records · Page 41Linked to original sources
PubMed1989

Computer system and software of POSITOLOGICA II: a whole body positron emission tomograph.

Since a whole body PET-scanner POSITOLOGICA II was installed at the National Institute of Radiological Sciences (NIRS) in 1982, improvements of the computer system and developments of new software have been continuously made to correspond to clinical requirements. As the result, POSITOLOGICA II possesses one of the most powerful systems and sophisticated software in Japan. This report describes the present status of the computer system and software of POSITOLOGICA II. It also discusses problems which still exist and proposes a future computer system for the PET study.

Brain↗
PubMed1989

[Case report of crowding treated without extraction].

In orthodontic diagnosis, one of the most important factors is to decide whether to extract or not to extract the permanent tooth. There are many so-called borderline cases. This difficulty is caused by his growth which can not be foreseen perfectly. We treated a borderline case without extraction, and established good occlusion.

Child↗
PubMed1989

[Analysis of 293 cases of hepatocellular carcinoma of recent ten years--I. Epidemiology, anamnesis and tumor occupying rate].

Two hundred and ninety-three cases of hepatocellular carcinoma (HCC) admitted to the key hospital of the rural area of western Japan, Saga Prefectural Hospital, during 10 years since 1979 to 1988 were analysed retrospectively. The male to female ratio was 3.7 to 1 and the ratio of HBs-Ag positive to negative was 3.5 to 1. The peak of the age distribution was seventh decade. The incidence increased annually, especially in HBs-Ag negative males. Their past history of blood transfusion was considered as an etiology of HCC in 19 (9.9%). The HCC was diagnosed approximately 10 years earlier in habitual drinkers than non-habitual drinkers of both positive and negative HBs-Ag. The incidence of small tumors is associated with the past history of chronic liver disease, negativity of HBs-Ag, lack of symptoms and old age.

Adult↗
PubMed1989

[Analysis of 293 cases of hepatocellular carcinoma of recent ten years--II. Diagnosis, therapy and prognosis].

Two hundred and ninety-three cases of hepatocellular carcinoma (HCC) of recent ten years during 1979 and 1988 were analysed on its diagnosis, therapy and prognosis. Angiography was the most useful diagnostic method for the first 5 years. During recent 5 years and for the tumor with size less than 2 cm, however, ultrasonography was the best method. 24.7% cases showed negative AFP and only 42.5% cases showed the level over 400 ng/ml. According to the tumor occupying-rate at the diagnosis, the number of cases of E1 had increased annually, the other cases being unchanged. 88.6% cases had liver cirrhosis microscopically as being reported previously. As a therapy TAE was most frequently performed, followed by operation, arterial infusion of antitumor drugs et al. The prognosis of the patients depended on the tumor occupying-rate. For the case of E1, the prognosis was the best by the therapy of ethanol injection therapy, operation and TAE. For the cases with tumor of larger than E1, frequent TAE was the best. From these results we concluded that we must make efforts to find small tumors to get the good prognosis.

Adult↗
PubMed1989

[Evaluation of the extended operation in stage 4 esophageal cancer].

For the last four years, 174 cases of thoracic esophageal cancer have been resected in our department. Stage 4 cancer cases were encountered in 73 cases (42%) of total resected cancer cases. As the location of lesion, 1m was most frequent in 52%, followed by Ei in 23%. The 2-year and 3-year survival rate were 25% and 17% respectively. Analyzing 73 cases of stage 4 cancer, a0-2n3,4 was found in 52 cases (71%), a3n0-2 12(16%), a3n3,4 7(10%) and M1 2(3%). Invasion to the trachea and bronchi was seen in 11 and that to the aorta was in 7. As for surgical procedures, the combined resection of the aorta was performed in two cases. The postoperative course was smooth, however, the prolonged survival was not obtained due to the recurrence of cancer. The lymph node metastasis was widely observed in the cervical region, mediastinum and abdominal cavity. The thoracic paratracheal lymph node metastasis was the most frequent. The lymph node dissection was necessary in these three regions. Especially the sufficient dissection in the upper mediastinal lymph nodes, that is, the right recurrent nerve nodes, the left recurrent nodes and the infraaortic arch nodes, was very important.

Aorta↗
PubMed1989

[Surgery of aortic disease with coronary heart disease].

From 1978 through 1989, 1200 patients underwent attempted coronary surgery. Seventy-six CABG-patients were recognized aorto-vascular disease. Thirty-one CABG-patients were operated with vascular surgery. Operative mortality of CABG was 0% (0/76). Operative mortality of vascular surgery was 3.2% (1/31). Total operative mortality was 1.1% (1/91).

Aortic Aneurysm↗
PubMed1989

[St. Jude Medical valve replacement: clinical experience with 1,039 patients].

St. Jude Medical valve replacement was performed in 1,039 patients; 320 had aortic (AVR), 543 mitral (MVR), and 176 had double valve replacement (DVR). There were 44(4.2%) early deaths. Follow-up extended in 995 patients from 10 to 130 months, with a cumulative period of 2,730 patients-years. The overall survival rates of AVR, MVR, and DVR patients at 10 years were 60.5%, 89.6%, 90.3% respectively. The linearized incidences of valve thrombosis, thromboembolism, anticoagulation-related hemorrhage, prosthetic valve endocarditis, and significant hemolysis were as follows: 0.11%/pt-yr, 1.33%/pt-yr, 0.04%/pt-yr, 0.18%/pt-yr, and 0.11%/pt-yr, respectively. There were no structural failure after 10 years follow-up. Reoperation (explant and re-replacement or suture repair) was required in 10 patients. Seven of them had periprosthetic leakage, 2 had valve thrombosis, and one underwent reoperation because of a technical error. Actuarially over 98% of patients were free of valve-related mortality at 10 years. St. Jude Medical valve is an excellent alternative for use in the surgical treatment of valvular heart disease.

Adolescent↗
PubMed1989

[Blunt injury of the vertebral artery: report of three cases].

The authors reported three cases, whose vertebral arteries had been injured by blunt trauma to the neck which was followed by cerebello-brainstem infarctions. Case 1: a 32-year-old man, who developed severe vertigo and nausea 7 days after a traffic accident. He showed neck pain and horizontal nystagmus on admission. Three days later, he became drowsy. CT scan of the head demonstrated right-side cerebellar infarction, and the angiography revealed an occlusion of the right vertebral artery at C4-5 level. After the removal of the right cerebellar hemisphere, he recovered neurologically and was discharged from the hospital, able to walk. Case 2: a 47-year-old man, who suddenly became comatose 6 hours after an accident. Plain CT demonstrated a highly dense basilar artery. Angiography revealed the occlusion of the left vertebral artery, and severe stenosis of the right vertebral artery. The basilar artery was not visualized. Anticoagulant therapy was started immediately. He survived, but he developed locked-in syndrome. Case 3: a 53-year-old man, who developed transient apnea after an injury. On admission, neurological examination showed horizontal nystagmus, weakness of his right upper limb, and sensory disturbance in the left side of the body. Neck traction was done for spinal C1 and C2 fractures. Twenty-one hours after the injury, he became comatose suddenly. The four-vessels angiography revealed the occlusion of both vertebral arteries. The basilar artery was visualized through the posterior communicating arteries. He died on the 6th day after the trauma.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1989

[Aortic wall injury and thrombogenesis in catheterization: experimental study].

Arterial and venous catheterization is a very useful procedure in the diagnosis of heart diseases. However, some complications with thrombogenesis have been reported. Two kinds of Mikaelson-type non-heparin-coated angiographic catheters (with 6.5 Fr. and 80 cm length) were used for the experiments. One was of polyurethane (PUC) and the other of polyethelene (PEC). Eight experimental dogs were used for each group. The catheter was inserted into the ascending aorta through the femoral artery. No antithrombogenic drugs were given to the animal. One hour later, sodium heparin (100 U/kg) was administered intravenously. The animal was sacrificed by acute exanguination. The aorta was opened longitudinally. The position of the thrombi on the aortic wall was macroscopically observed and the weight of the thrombi attached to the catheters were measured. A piece of the aorta at each level was excised for light and scanning electron microscopic observations. Mural thrombi of various lengths still remained on the aortic wall of every dog after the removal of the catheters. Microscopic observation revealed that the mural thrombus was formed on the aortic wall, where the endothelial cells had peeled off and the internal elastic membrane was partially destroyed. SEM observation also showed that fibrin network on the aortic wall where the endotherial cells were peeled off. Microscopic observation of aortic wall also revealed intimal tears, inner elastic membrane injury and bleeding in the elastic membrane. This damage could worsen leading to dissection of the aorta, thrombosis of the abdominal organs. The injury is considered due to mechanical irriation by the catheter.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1989

[Clinical and laboratory studies in seven patients with pre-B cell leukemia in children].

We have experienced and treated seven patients of pre-B cell leukemia in childhood. Clinical, cytological and ultrastructural characteristics of them were studied. Most of them had higher counts of white blood cells, hepatosplenomegaly, high value of lactic dehydrogenase and various karyotype abnormalities at onset. The chromosomal translocation t (1; 19) that is supposed to be specific to pre-B cell ALL was found in four of seven of our cases. In the seven patients, survival was studied in comparison to that of 27 common ALL patients at our hospital that are common in childhood acute leukemia. Although no difference in remission duration and survival time between pre-B cell ALL patients and common ALL group, there have been seen the tendency that remission and survival were of shorter duration for patients with pre-B cell ALL.

Child↗
PubMed1989

[Cardiac surgery in chronic dialysis patients: usefulness of continuous ambulatory peritoneal dialysis (CAPD)].

Eleven chronic dialysis patients underwent cardiac surgery in the past six years. Six of these cases had coronary artery disease, three had valvular heart disease and the other two had congenital heart disease. Of those 11 patients, 5 cases were successfully maintained on CAPD in the pre- and post-operative period. The remaining 6 patients were treated with hemodialysis before the operation and received intermittent peritoneal dialysis or hemodialysis following cardiac surgery. Intraoperative hemodialysis was carried out in 9 cases under cardiopulmonary bypass. There was one early death of low cardiac output syndrome, and two patients died of brain hemorrhage in the late post-operative period. Both of the latter two had hypertension and were maintained on hemodialysis under anticoagulant therapy. The other 8 are doing well and 5 of them are on CAPD. These results suggest that the procedure without anti-coagulation and/or CAPD should be chosen for the cardiac operation of chronic dialysis patients with hypertension.

Adult↗
PubMed1989

[A case of right aortic arch with the stenotic left subclavian artery at its origin complaining of left nuchal pain].

A 25 year-old male was transfered to our department with a complaint of left nuchal pain. Angiography revealed a right aortic arch with the stenotic left subclavian artery at its origin and poor left vertebral artery. The anomaly was classified an intermediate type of Stewart type (2) and (3). It was very rare and we have found only 3 same cases in literature. The complaint disappeared after the ascending aorto-left subclavian artery bypass.

Adult↗