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Biomedical subjects

M Elias

Publications and source records attributed to M Elias.

At least 91 records · Page 5Linked to original sources
PubMed1985

Results of therapy in adult acute nonlymphoblastic leukemia: experience in Jerusalem, Israel, during 1975-1982.

78 previously untreated patients (aged 16-82 years) with acute nonlymphoblastic leukemia received intensive chemotherapy for induction of remission. In 64 patients, the combination used consisted of daunomycin and cytosine arabinoside with or without 6-thioguanine. The overall remission rate was 59 and 87% for those who received what was considered as adequate therapy. Patients who achieved remission received maintenance and, in part, late intensification. The median duration of remission was 9 months. The median survival of the patients who attained remission was 24 months, compared to 15 months for the entire patient group and 3 months for patients who failed to achieve remission. Age had no effect on the rate and duration of the remission obtained but the median survival was significantly longer in patients below the age of 50 years.

Adolescent↗
PubMed1985

DDT--susceptibility status of Anopheles philippinensis--a mosquito vector of malaria in Bangladesh.

DDT-susceptibility tests conducted on An. philippinensis Ludlow in 1979 and 1980 and several previous years of observations made during malaria programmes in different areas of Bangladesh have been reported. The LC50 value for 1980 was found to be 0.74% DDT showing 2.96 and 1.85 fold increase of tolerance level from 1961 (0.25%) and 1976 (0.4%) respectively. The tests showed that the species continues to be susceptible to DDT in Bangladesh. However, the changes in LC50 over the years may indicate a slight acquisition of "vigour tolerance."

Animals↗
PubMed1984

Thromboembolism in patients with the 'lupus'-type circulating anticoagulant.

Thirty-five patients with the lupus anticoagulant (LA) were followed up between 1975 and 1982. The most prevalent clinical manifestation occurring in these patients was thrombosis. Nineteen patients (54.3%) had a single or recurrent thrombotic episode. Fifteen patients (42.8%) had venous thrombosis, and arterial thrombosis manifested by stroke or transient ischemic attacks occurred in six patients. Bleeding occurred in only five patients, four of whom had severe thrombocytopenia, while no excessive bleeding was noted during 18 operative procedures. Various therapeutic regimens, including corticosteriods, nonsteroidal anti-inflammatory drugs, cytotoxic or immunosuppressive agents, had no effect on the presence of the LA in these patients. Anticoagulants were successful in the treatment and prevention of thrombotic episodes.

Adolescent↗
PubMed1982

The development of neocortical noradrenergic innervation in the mouse: a quantitative radioenzymatic analysis.

The concentration of norepinephrine (NE) in the neocortex of the mouse has been determined radioenzymatically from the thirteenth embryonic (E13) through the sixtieth postnatal (P60) days. Detectable levels of the transmitter are present on E14, coincident with the emergence of the cortical plate. NE concentrations increase rapidly thereafter to reach a level 57% of adult values by P4. Subsequently, through P8 there is a decline followed again by a more gradual rise to maximum, or adult, concentrations by P30.

Aging↗
PubMed1981

DDT-susceptibility status of malaria vector Anopheles balabacensis balabacensis Baisas (Diptera : Culicidae) in Bangladesh.

DDT-susceptibility tests on Anopheles balabacensis balabacensis Baisas carried out during several years especially during 1979 and 1980 in Sylhet district have been reported. The LC50 value for 1980 was found to be 0.88 +/- S.E. 0.02 showing 2.38 fold increase of tolerance from 1970 (LC50 = 0.37 +/- S.E. 0.07). The species is still found to be susceptible to DDT in Bangladesh. The implication of the use of DDT in controlling malaria due to this species is also discussed.

Animals↗
PubMed1980

The feasibility of dental strontium analysis for diet-assessment of human populations.

It has been suggested that bone and dental strontium contents of extinct terrestrial vertebrates vary in direct proportion to the strontium levels present in the animals' diets. It has been hypothesized that these trace quantities decrease as one moves upward along the food chain--herbivores having more strontium than primary carnivores, primary carnivores more than secondary carnivores, and so on. The present study was designed to determine the feasibility of dental strontium analysis for diet-assessment of human fossil populations. Human vegetarian and nonvegetarian teeth were analyzed for strontium. It was hoped that by comparing the strontium levels of these two groups, one might determine conclusively whether the nature of diet plays an important role in the determination of dental strontium levels within a species. Atomic absorption spectrophotometry was used to analyze seven vegetarian and seven nonvegetarian teeth. Strontium levels varied considerably within both groups of teeth and no significant difference in strontium levels existed between the vegetarian and nonvegetarian teeth. These results suggest that dental strontium analysis may not be a useful indicator of the dietary habits of human fossil populations.

Dental Enamel↗
PubMedDate not supplied

Malaria and Borrelia co-infection.

Severe anemia requiring blood transfusion may complicate falciparum malaria, but is rare in nonfalciparum malaria. We present a case of a young man with high fever, severe hemolytic anemia, and a blood film containing massive co-infection with Plasmodium vivax and with Borrelia. The possible importance of the co-infection on the magnitude of hemolysis will be discussed.

Adult↗