Allergic bronchopulmonary aspergillosis.
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Aspergillosis, Allergic Bronchopulmonary↗
Biomedical subjects
M E Peters
Publications and source records attributed to M E Peters.
Congenital partial eventration of the left diaphragm.
Two unusual cases of congenital partial eventration of the left diaphragm in young infants are described. In both cases the entity appeared as a space occupying lesion in the left anterior chest and was initially thought to represent pericardial cyst, mediastinal tumor, or cardiac enlargement. The left lobe of the liver occupied the eventration in both cases; one was proven at surgery, and the other was documented with a radionuclide liver scan. The radiographic features of eventration are discussed and the role of radionuclide liver scanning in infants with chest masses is emphasized.
Diaphragmatic Eventration↗
Congenital bladder duplication and diverticulum.
Evaluation of urinary infection in a 5-month-old male infant revealed duplication of the prostatic urethra and bladder. Associated anomalies were a right bladder diverticulum, left vesicoureteral reflux and bowel duplication.
Abnormalities, Multiple↗
Respiratory abnormalities among grain handlers: a clinical, physiologic, and immunologic study.
A survey of 300 grain elevator workers revealed that 77 per cent complained of eye symptoms; 64 per cent, of nasal symptoms; and 88 per cent, of one or more respiratory symptoms on exposure to airborne grain dust. Symptoms on exposure were independent of age and length of employment. Cough and wheezing on exposure were more common among smokers than nonsmokers (P less than 0.025). Nineteen per cent of the workers had had episodes of grain fever. The prevalence of chronic bronchitis was 37 per cent (42 per cent of smokers and 30 per cent of nonsmokers). Wheezes on auscultation were found in 23 per cent. Measurements of lung ventilatory function, as well as diffusing capacity, correlated significantly with age and smoking habits, but not with length of employment. Thirty-seven per cent of the workers had an abnormal mean forced expiratory flow during the middle half of the forced vital capacity (47 per cent of smokers and 13 per cent of nonsmokers), and 34 per cent had an abnormal maximal expiratory flow after exhalation of 50 per cent of the forced vital capacity (40 per cent of smokers and 13 per cent of nonsmokers), whereas only 13 per cent had an abnormal ratio of 1-sec forced expiratory volume to forced vital capacity. There was no correlation between precipitins to fungi, bacteria, grain, or grain dust antigens and acute or chronic respiratory symptoms, lung function, or grain fever. There was, however, a significant correlation between cutaneous reactivity to grain dust and wheezing on exposure (P less than 0.02). Abnormal flows at low lung volumes were more common among cutaneous reactors to common allergens. We concluded that exposure to airborne grain dust can cause acute inflammatory reaction to the exposed mucosa, and it is highly probable that grain dust contributes and, in some cases, causes chronic airway disease.
Adult↗
The value of precipitating antibodies in screening for hypersensitivity pneumonitis.
To evaluate the usefulness of precipitin tests as a screening method to detect hypersensitivity pneumonitis, we compared persons with precipitins to organic antigens with precipitin-negative subjects from the same population of 1,072 office workers participating in a health survey examination. Thirty-three of the 53 persons with preciptins to Micropolyspora faeni, Thermoactinomyces vulgaris, T. candidus, pigeon serum, aspergillus, alternaria, pullularia, penicillium, cephalosporium, trichoderma, and phoma were matched according to age, sex, height, and smoking habits with precipitin-negative subjects. The subjects completed a self-administered standard questionnaire, they were interviewed and examined, chest radiograms were taken, and pulmonary functions were evaluated at rest and during mild and moderate exercise. No significant differences were found between the 2 populations in any of the pulmonary function measurements. In addition, clinical and radiologic evidence failed to distinguish between the 2 groups. No cases of hypersensitivity pneumonitis were found. In this population, precipitins had no apparent relationship to long disease. The frequency of precipitins was considerably higher than the frequency of hypersensitivity pneumonitis. We concluded that the detection of hypersensitivity pneumonitis in population surveys attempting to establish prevalence of the disease cannot be accomplished by the simple analysis of serum precipitating antibodies but requires, in addition, a more complex analysis of historical, radiologic, and immunologic data.
Antigens↗
Giant colonic ulcers associated with Hirschsprung's.
Giant colonic ulcers are described in an infant with Hirschsprung's associated with enterocolitis.
Colitis, Ulcerative↗