Search PubMed⌕ Search

Biomedical subjects

M De Marchi

Publications and source records attributed to M De Marchi.

119 records · Page 7Linked to original sources
PubMedDate not supplied

[Specificity, sensitivity and reproducibility of 2 methods of determining serum immunocomplexes (solid-phase C1q and polyethylene glycol precipitation)].

In the last years a few tests for the detection of circulating immune complexes (CIC) have been published. Nevertheless the data concerning their sensitivity and reproductibility are often partial. The Authors have here analysed, following this point of view, two methods for the detection of CIC, based on different mechanisms and therefore able to identify different kinds of CIC; the tests are: the PEG precipitation test and the C1q solid phase method. The reproductibility of the two methods is good, even when the samples have been many times thawn or kept at 20 degrees C for a few weeks; C1q test sensibility appears distinctly better than PEG test sensibility. By the two methods, but particularly with the PEG, it is possible to identify fluctuation of the IC levels during the day. The contemporaneous use of these two techniques can give results really useful to clinically monitorize some immune complexes diseases, such as many human glomerulonephrites.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Solid-phase conglutinin tests for circulating IgA immunocomplexes].

In some renal, gastroenterological and dermatological diseases the pathogenic role of circulating immune complexes (CIC) of IgA type has been defined. The methods so far proposed to investigate CIC are for the most part able to identify IgGIC, while only few can do the same for IgAIC. The Authors discuss in details the technique and the sensibility and specificity of a new test for IgAIC based on the linkage with the conglutinin in solid phase and propose this test for the clinical study of IgA diseases.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Endoscopic treatment of cicatricial and neoplastic esophageal stenosis].

Eder Puestow's dilatation technique in association with fiberendoscopy was used in ten patients with oesophageal scar stricture and in fifteen patients with oesophageal neoplastic stricture. In ten of the latter patients an endoesophageal prosthesis was endoscopically inserted by Nottingham's method. In describing the methods and results obtained the authors stress the absolute reliability and advantages offered by such techniques.

Adult↗
PubMedDate not supplied

[Neurosheet: an electronic sheet for neurosurgical intensive care].

PURPOSE: A growing number of monitoring and diagnostic instruments has considerably increased the amount of information available in the intensive care unit. A data collection system which can be useful in highlighting and processing the most relevant data for the care of head-injured patients (Neurosheet) has been set up. The purpose of this study is to describe Neurosheet and to analyse the results achieved through its use. ENVIRONMENT: Neurosurgical Intensive Care Unit. METHODS: Neurosheet consists of a data sheet which follows the course of some "key" variables in head-injured patients who undergo ICP monitoring for a period of more than 48 hours. SURVEY: Through a questionnaire distributed to the medical staff, the learning period and the opinion of the staff concerning the clinical usefulness of this instrument has been evaluated. The amount of time needed to compile Neurosheet has been measured and some criteria indicating its completeness identified. RESULTS: It has been found that Neurosheet can be learned quickly and is rather easy to use. Data resulting from the study of the learning curve and from the answers to the questionnaire, suggest that its learning period is quite short (10 to 20 minutes). Among the 28 eligible patients, Neurosheet was used for 24 (86%). The data collected show 1,912 hours of monitoring, with an average of 112.8 (+/- 55) hours per patient. Neurosheet was completed in 83% of the cases. CONCLUSIONS: The aim of Neurosheet is to provide an answer to the overload of information using computerised systems able to simplify and support the daily clinical work.

Critical Care↗