Beware before concluding: one anemia can hide two others.
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Biomedical subjects
Publications and source records attributed to M David.
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The authors report a statistical analysis of 163 operations of aorto-iliac vascular surgery. A detailed study of their 14 deaths showed the various causes of mortality (immediate post-operative thrombosis, acute renal failure, digestive complications, septic cardiac, pulmonary, hemorrhagic and cerebro-vascular accidents). This analysis, compared with the findings in all the operated patients showed the main factors of risk in this type of surgery (age over 70 years immediate and late reoperations, heart lesions, renal, pulmonary and late lesions, the risk of sepsis). The indicate the means of prevention of such accidents and the therapeutic attitude when they occur. They conclude that the contra-indications are relative, but should be observed in order to lower the risk of this surgery below 5 p. cent mortality rate.
The paper presents several remarks on opportunity and usefulness of the centre for outpatient follow up of glaucoma within the "Colţea" Ophthalmology Clinic and of the Bucharest Municipal Hospital. The unconfirmed, suspected patients were not considered glaucomatous. The exam of the eye has to be complete, to include the systematic investigation of the ocular tension, and of the visual field, by evidencing scotoma in Bjerrum's area photometric disharmonies and chromatic alterations. A special attention must be paid to the low pressure glaucoma, as a peculiar evolution form of glaucoma with open angle.
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Among 59 children presenting with congenital adrenal hyperplasia due to 21-hydroxylase deficiency observed between 1976 and 1982, 12 (9 males, 3 females) aged 3 1/2 to 12 years, were treated with medroxyprogesterone acetate (MPA) associated with the usual glucocorticoid and eventually mineralo-corticoid treatment. There were two indications: precocious puberty after the onset of the gluco-mineralo-corticoid treatment; Unbalanced biological status with advancement of bone maturation. After the onset of MPA, a decrease in plasma 17-hydroxyprogesterone (17 OHP) and testosterone levels is observed, the bone maturation speed decreases when growth in height continues. MPA may be a contributive treatment for congenital adrenal hyperplasia due to 21-hydroxylase deficiency, permitting restoration of biological balance by restraining adrenal function and improving the final height prognosis.
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Three cases of bone hydatidosis of pelvis with invasion of soft tissues provided data on the effectiveness of CT scan and ultrasound imaging for diagnosis, evaluation of extension and follow up surveillance of this affection. Two of the three patients treated medically were followed up by review CT scan and ultrasound examinations. The two techniques were found to be effective for detecting recurrence and for surveillance of hydatid lesions of soft tissues during medical therapy.
A double-blind multicentre study was undertaken in French-speaking African countries, using parallel series in 34 SC homozygous or double-heterozygous subjects suffering from vasculo-occlusive sickling crisis. In the patients treated with dihydroergotoxine, there was a reduction in the duration of the episodes by 43 hours, i.e. more than one quarter of the total duration. This decrease was statistically significant (p is less than 0.05).
The authors define their approach to vascular function tests (VFT) and the situations in which they may be useful in the diagnosis of complicated, associated or secondary venous disease. They present various pathological cases (superficial phlebitis, swollen leg, calf pain, deep venous obstruction syndrome, intermittent claudication, subacute ischaemia, trophic disorders). In general, VFT are able to: demonstrate the haemodynamic signs of venous stasis, recognise and analyse the various forms of diabetic angiopathy and quantify the degree of ischaemia in the presence of PVD associated with venous symptoms. VFT are particularly useful when the problems to be studied have been carefully defined by means of a thorough clinical examination.
An assay for urinary gonadotropins (UG) performed after acetone extraction is presented. This dosage was performed either on a sample of the 24 assay urine, or on the fractionated 12 hr/12 hr urines (night/day) in normal children whose ages ranged from 2 to 20 years and in children presenting with various endocrine diseases (on about 2,000 urine samples). Normal values were established according to sex and stage of puberty. In boys, the lack of overlap between values of LH (UI/24 hr) observed in stage I (prepubescent, 9-13 yrs) and those observed in stage II represents an obvious biological marker of the onset of puberty. The night/day ratio of LH also increases close to puberty, reflecting the onset of the well-known night secretion of LH, at the time of the first stages of puberty. In girls, the preferential increase in FSH is the best criterion for the onset of puberty. In children with endocrine diseases, assay for UG/24 hr is a valuable parameter of the gonadotropic function allowing 1. to separate delayed puberty from hypogonadotropic hypogonadism; 2. to confirm a diagnosis of precocious puberty and 3. to control a treatment with LHRH analogous.
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