Search PubMed⌕ Search

Biomedical subjects

M Clarke

Publications and source records attributed to M Clarke.

At least 307 records · Page 17Linked to original sources
PubMed1981

Safety of Debendox.

Explore the source record for details and available documents.

Abnormalities, Drug-Induced↗
PubMed1981

The design and interpretation of case-control studies of perinatal mortality.

The difficulty of designing prospective studies of perinatal death makes the case-control study a method of choice. The particular problems associated with the identification of risk factors, the definition and enumeration of cases, and the selection of live birth controls in such a study, undertaken on all perinatal deaths occurring in a population of 850,000 people during 1976-1978 are described. The method of control selection, chosen for reasons of feasibility, produced a nonrepresentative sample of controls. This was because controls were selected as the next live birth in the place of delivery where the perinatal death delivery occurred, which resulted in a sample stratified by place of delivery. Knowledge of the place of delivery of all births allowed a correction to be undertaken which was derived from the relative weights for the strata within which matching had occurred.

Data Collection↗
PubMed1980

Isolation and properties of calmodulin from Dictyostelium discoideum.

A calcium-dependent regulatory protein (calmodulin) was purified from vegetative amoebae of Dictyostelium discoideum. The properties of Dictyostelium calmodulin are similar but not identical to those of bovine brain calmodulin. Calmodulin activity was not detected in extracts of Saccharomyces cerevisiae or Escherichia coli.

2',3'-Cyclic-Nucleotide Phosphodiesterases↗
PubMed1980

The elderly in residential care: mortality in relation to functional capacity.

A census in which 4514 people aged 65 and over had been enumerated in all types of institutional care both within and outside the National Health Service in Leicestershire was taken as a starting point for the present investigation. This entire population was followed up for one year to determine its mortality experience. Mortality was described by three measures: (a) the proportion surviving for one year from the date of the census, (b) the standardised mortality ratio (using the population of Leicestershire in 1977 as a standard), and (c) using a life-table analysis, the percentage survival to specified time periods after admission to institutional care. We discuss the relationship of these indices to functional capacity, indicated by the ability to undertake basic activities of daily living (ADL), and to type of institution.

Activities of Daily Living↗