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Biomedical subjects

M Block

Publications and source records attributed to M Block.

At least 163 records · Page 9Linked to original sources

Life stress and maladaptation of children.

Social environmental variables differentiating maladapting children from matched controls in four inner-city elementary schools were investigated. Teacher selection was used to identify the maladapting children. Identified maladapting children were more likely to have been on welfare and to have experienced significantly more stressful life events during the previous year than the matched control children. The maladapting group was subdivided into welfare and non-welfare groups. Comparisons between groups on the life stress event measures indicated that the nonwelfare maladapting group experienced more life events than either the nonwelfare controls or the maladapting welfare children. The measures of life events correlated with parent ratings of behavior problems for the nonwelfare maladapting group but not for the welfare maladapting or the control groups.

Adaptation, Psychological↗

Osteomalacic new bone formation during chemotherapy of acute granulocytic leukemia.

The development of a rapid rate of regeneration of osteomalacic bone in a patient treated for acute granulocytic leukemia has been demonstrated for the first time. This positive bone balance was most intense at the time of maximal depletion of leukemic tissue. The authors postulate that new formation of osteomalcic bone is due to inability to maintain the rate of calcification parallel to that of bone formation. A similar abnormality occurs in egg-laying birds, in rapidly growing children on a diet suboptimal in vitamin D who have rickets, and in some patients with osteoblastic metastases.

Bone Marrow↗

Triiodothyronine uptake test in which antibody-coated tubes are used compared to two other tests in which precipitation separations are used.

A triiodothyronine uptake test in which antibody-coated tubes are used (Clinical Assays) was compared to two other such tests in which silicate tablets (Nuclear-Medical Laboratories, Inc.) or macroaggregated albumin (Diagnostic Corporation of America) are used to separate the bound from the free fraction. The Clinical Assays test showed good linear correlation with the values obtained by the other two tests on 67 samples. The interassay coefficient of variation was 4.8%. The correlation between the values obtained and the clinical evaluation on 60 patients also was essentially the same as for the other two tests, 80%.

Antibodies↗

Clinical implications of lactose-positive breast secretions in nonpuerperal females.

Inappropriate milk-like secretion from the breasts is not infrequently encountered in patients. Usually these secretions have been identified as milk on the basis of their characteristic appearance, and only rarely has their identity as milk been proven by appropriate analysis. Since milk is chemically defined as a lactose-containing mammary secretion, the presence of lactose in a breast secretion identifies it as milk irrespective of its appearance or the presence of other constituents. Lactose can be readily identified by thin-layer chromatographic methods, which despite their inherent speed and sensitivity have not been widely utilized. A method using commercially prepared cellulose layers and a sandwich developing apparatus is presented in detail. This method utilizes current advances in chromatographic techniques and permits rapid and accurate identification of lactose in breast secretions. Such secretions from 10 nonpuerperal women were screened for the presence of lactose. The milk-like secretions from 8 contained varying amounts of lactose, which was not detectable in the secretions from the other 2. There was no correlation between the appearance of the secretion and the presence of lactose.

Breast↗