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Biomedical subjects

M Berger

Publications and source records attributed to M Berger.

At least 1,009 records · Page 56Linked to original sources
PubMed1978

[Rapid technic for preparation of thyroid ribonucleic acids without phenol].

Thyroid tissue was homogenized in 2 M LiCl. The homogenate was alloued to stand 1 h 30 min at 2 degrees C and then centrifuged. The pellet was suspended in 5% triisopropylnaphthalene sulfonic acid (the sodium salt), 0.05 M Tris--HCl, and 0.1 M NaCl (pH 8). After stirring and centrifuging, the supernatant containing the crude RNA was purified by filtration on Ultrogel AcA 22 (LKB, Sweden). Before adding the sample of crude RNA to the column, pronase was placed on the column. When pronase had entered the gel, we added the sample. The first peak contained pure RNA plus some DNA. The former was precipitated with 2 M LiCl. The RNA species obtained by this technique were undegraded and the yield was 30% better than that of the phenol technique.

Animals↗
PubMed1977

[Incidence of obesity in hospitalised patients 1933-1972 (author's transl)].

Analysis of 31 686 patient records for obesity among hospitalised patients in the Second Medical Clinic of Düsseldorf University between 1952 and 1972 demonstrated a steep rise to a plateau of 24 +/- 2% in 1956-1972. Adding a corresponding analysis from the Bonn Medical University Clinic some 66 000 hospitalised patients could be included for a period of 40 years. Socio-economic conditions in the war and post-war period produced a marked fall in obesity to a minimum of 2% in 1946. The mean incidence before 1935 was 10%, by 1958 it had increased two-and-a-half fold. It is thought that this had been due not to a corresponding higher calorie intake by the population but rather a general reduction in physical activity. The increase in obesity among the population, reflected in these hospital statistics, is likely to lead to a parallel increase in cardiovascular risk factors and with it the ever-rising curve of death from cardiovascular disease in the Federal Republic of Germany.

Cardiovascular Diseases↗
PubMed1977

[Psychological problems in obesity (author's transl)].

The MMPI was administered to 209 obese women and 72 obese men before onset of a weight reduction regime. Obese subjects differ in a variety of MMPI-standard-scales from the standard population as well as from a control group of healthy women: 1. Scales Hypochondriasis (Hs) and Hysteria (Hy) have significant higher values for the obese. This somatic impairment grows in the group of obese women with increasing age and obesity. In men, scale Hs corresponds to the degree of overweight but the youngest male age group (up to 19 years) has a Hs-peak as well as men above 35 years of age. 2. Higher than normal values for obese men and women in scales Depression (D) and Psychasthenia (Pt) in the obese point towards emotional upset. 3. Obesity does not decrease Hypomania (Ma) values for men or women; to the contrary: obese men felt more active than the standard population. With growing age women had a decrease in Ma-values.

Adolescent↗
PubMed1977

Utility of ultrasound in the differential diagnosis of acute cholecystitis.

Three case reports show the usefulness of ultrasound examination in patients with right upper quadrant masses despite clinical or roentgenographic evidence of cholecystitis or cholelithiasis. In one patient an hepatic fungal abscess from Candida albicans was distinguished from the gallbladder; in another, the same was possible for a pyogenic abscess in an old surgical incision; and in a third, extension of a gallbladder carcinoma to the liver was distinguished from the gallbladder itself. Thus, the ultrasound examination allowed assessment of the relationship between the clinically palpable mass and ultrasonically defined anatomy, When needed, increased specificity of diagnosis was obtained by ultrasonically guided fine-needle aspiration biopsy.

Adult↗
PubMed1977

The ultrasonic demonstration of gastric lesions.

Fifteen cases of circumferential gastric antral disease identified by upper gastrointestinal (GI) series over a 12-month period were studied by a gray-scale ultrasound. In 93 per cent of the patients studied, a characteristic ovoid anechoic area containing a dense central collection of echoes was identified. The abnormality was located in the midline or slightly to either side, just dorsal to the inferior margin of the liver on longitudinal sections. The lesions studied included primary and secondary malignancy, lymphoma, corrosive gastritis, and granulomatous disease of childhood. In each instance a barium study of the stomach confirmed the location of the lesion. A prospective study of 50 normal individuals revealed one patient in whom the characteristic appearance was found at ultrasound and who subsequently had a normal upper GI series. Thus, although the ultrasound appearance of antral thickening may rarely be found in normal individuals, this characteristic appearance should strongly suggest gastric pathology, necessitating an upper GI series.

Adolescent↗