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Biomedical subjects

M Bühring

Publications and source records attributed to M Bühring.

28 records · Page 2Linked to original sources
PubMed1982

[Tissue damage following paravenous cytostatic drug application. An additional treatment with percutaneous electric nerve stimulation].

Some aspects in the development of severe tissue damage after an adriamycin extravasation are considered as a sympathetic reflex dystrophy syndrome. In this, a peripheral stimulus (e.g. pain) activates efferent autonomic and motor nerves resulting in vasomotor changes and other "dystrophic" changes in soft tissues. A typical state is the Sudeck's dystrophy syndrome. With a transcutaneous electrical nerve stimulation it should be possible to interrupt this vicious circle. A case with a good clinical result is reported.

Aged↗
PubMed1981

[Acute virus hepatitis and venereal infection (author's transl)].

100 patients with acute viral hepatitis were examined. In 10 of these the infection was found to be associated with homosexual activity and in 7 with promiscuity. Sexual intercourse was a likely cause of infection in 61% of all men aged from 20-40 years who had contracted hepatitis B by a non-parenteral route. Of these patients, 8 had acute syphilis and 2 had acute gonorrhea along with their hepatitis. The clinical course of the hepatitis was more severe in the group of syphilitic patients than in the controls. These observations indicate that simultaneous venereal disease influences the incidence and course of acute viral hepatitis.

Acute Disease↗
PubMed1979

[Sympatho-adrenal activity in acute cold stress. The mechanism of sudden death following water immersion].

In addition to currently known mechanisms of sudden death following water immersion, predominantly vagal cardio-depressive reflexes are discussed. The pronounced circulatory centralization in diving animals as well as following exposure to cold water indicates additional sympathetic activity. In cold water baths of 15 degrees C, our own measurements indicate an increase in plasma catecholamine levels by more than 300%. This may lead to cardiac arrhythmias by the following mechanism: Cold water essentially induces sinus bradycardia. Brady- and tachyarrhythmias may supervene as secondary complications. Sinusbradycardia may be enhanced by sympathetic hypertonus. Furthermore, ectopic dysrhythmias are liable to be induced by the strictly sympathetic innervation of the ventricle. Myocardial ischemia following a rise in peripheral blood pressure constitutes another arrhythmogenic factor. Some of these reactions are enhanced by alcohol intoxication.

Adult↗
PubMed1978

Peripheral T lymphocytopenia under exogenous thermal stress.

A transient decrease in T lymphocytes in peripheral blood was observed in twelve healthy volunteers immersed in hot water baths which raised their mean rectal temperature by 1.35 C. T lymphocytes declined from 59 to 41 rel % (2p less than 0.001) or from a mean of 1990 to 1300 per mm3. T lymphocytopenia was accompanied by a relative increase in the fraction of B lymphocytes. Total lymphocyte count remained unchanged. In vitro heating alone to 39 C did not influence the total of SRBC-labelled lymphocytes. The findings are interpreted to be the result of a change in lymphocyte distribution with increased recirculation of mobile T lymphocytes.

Adult↗
PubMed1977

[Quantitative changes in peripheral T-lymphocytes during hyperthermia (author's transl)].

A uniform, highly significant fall in T-lymphocytes in the peripheral blood, without any change in the absolute lymphocyte count occurred in 6 healthy test subjects in a standardized hyperthermal bath with a mean rise in the rectal body temperature of 1.35 degrees C. A redistribution from the blood into the tissue structures of the rapidly recirculating T-lymphocytes in the body is assumed. The clinical significance of this redistribution cannot yet be stated. With increased recirculation of immunoreactive T-lymphocytes an increased contact with antigenic material in the tissues traversed would be possible. This could be the basis of the "immunostimulation" during hyperthermia assumed by some authors.

Adult↗
PubMedDate not supplied

[Reflex dystrophy following so-called whiplash injury of the cervical spine].

In bad cases of whiplash injury of the cervical spine the post-accidental course is complicated by pain, vegetative dysfunctional syndromes and by psychic and psychiatric disorders over many years. There is no satisfactory concept to understand the pathophysiology of these processes. The paper deals with the possibility of a reflex dystrophy. Sympathetic reflex dystrophy syndromes are seen principally in patients with joint, tendon or vascular lesions. In case of whiplash injury, it would concern the cervical spine itself as well as visceral organs including the central nervous system. For the CNS the lymphostatic encephalopathy is a well defined entity. Above all, a reflex dystrophy develops on the basis of a special personality structure. In case of psychic and psychiatric complaints after whiplash injury patients with a so called Sudeck-personality should not be suspected to aggravate; in contrast, especially in these patients complications by reflex dystrophy are credible. Consequences for the assessment and for rehabilitation are discussed.

Brain Diseases↗