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Biomedical subjects

M Bühring

Publications and source records attributed to M Bühring.

At least 19 recordsLinked to original sources

Course in massage therapy for medical students.

Massage courses for medical students have been held at Frankfurt University Medical School since 1987. To evaluate the motives for participation and to record possible changes in the attitude towards massage therapy, the students were asked to fill out a standardized questionnaire in 1990, 1993 and 1995/96. The results show that the motive for participation and the attitude towards massage therapy remained widely unchanged during these years. Summarizing all data (n = 199) the motives for participation were: (1) to practise massage therapy (86%), (2) to be better able to (later) prescribe massage therapy (66%), (3) to improve palpation skills (75%), (4) to do 'something practical' (56%), and (5) to (later) practise massage therapy as a medical doctor (23%). On average, the proportion of theory and practical instruction of 1:3.2 was considered suitable.

Adult↗

Unchanged response to stimulation of pituitary hormone release after serial UV irradiation in men.

A group of 24 healthy young men were evaluated before and after serial suberythematous ultraviolet (UV) radiation: group I, control (no irradiation); groups II and III, 12 radiations in 4 weeks with two different spectra (both containing UV-B). Before the first and 2 days after the last exposure all the volunteers were given an intravenous injection of thyrotropin releasing hormone (TRH, protirelin 0.2 mg) and luteinizing hormone releasing hormone (LH-RH, gonadorelin 0.1 mg). The serum concentrations of TSH, follicle stimulating hormone, LH and prolactin were measured at 0, 20, 30, 45 and 60 min by radioimmunoassay. Neither basal nor stimulated levels of the pituitary hormones showed significant changes after UV radiation. The results showed that exposure to suberythematous doses of UV did not influence the regulation of pituitary hormones in these healthy individuals.

Adult↗

[Special therapeutic practices from the viewpoint of naturopathy].

Naturopathy being orientated towards natural science and conventional medicine does not lead to basically different judgements about unconventional treatments nor about special therapies such as homeopathy, phytotherapy or anthroposophic medicine. It may, however, be more open-minded towards new ideas and theoretical even philosophical concepts and it is more likely used to question the 'state of the art' of actual medical knowledge. It is only for a relatively small part of unconventional treatments, that naturopathy recognizes a certain plausibility, which causes scientific investigation of the method to be meaningful. Naturopathy sometimes proposes traditional anthropologies and nosologies to be used for the election of suitable indications. A variety of psychologic effects of different methods of naturopathy may not be excluded by protocols used for clinical studies. As far as the majority of unconventional and paramedical treatments is concerned, naturopathy raises ethical beside scientific objections. Beyond a probable success of the treatment, it insists on a certain rationale and intellectual honesty. A differentiation between the more pragmatic interests of a health insurance and the scientific obligations of university medicine is given. An important and decisive criterium for the health insurances results from the demand for economics.

Complementary Therapies↗

[Connective tissue massage].

Connective tissue massage deals with the skin and the subcutaneous tissue. It focuses on definite regions of the body, assigned in segmental order to inner organ systems and structures of the locomotor system (spinal cord, joints, muscles). In case of acute disease, oedematous swelling of a generally soft tissue consistency can be observed in circumscribed areas. Persisting symptoms may result in induration of such tissues, associated with reduced rheology and epicritic pain if manipulated mechanically. Eventually, chronic conditions may progress to atrophy. The name "connective tissue massage" is based on the concept that corresponding physiological events take place in connective tissue structures and the segmentally associated organ. With regard to the pathophysiology of such zones, mechanisms which are comparable to sympathetic reflex dystrophy are discussed at present. Analysis of such changes has contributed to general diagnosis. Connective tissue massage is considered to be an important element of physiotherapy. The clinical data on the efficacy of connective tissue massage are reviewed.

Chronic Disease↗

[Pain in chronic arterial occlusive disease--the effect of improved macrocirculation on pseudo-radicular irritation].

In chronic obliterating arteriopathy the maximum walking distance does not correlate well with the ankle arm index of arterial pressure measured by Doppler ultrasound. Beside reduced macrocirculation and microcirculatory maldistribution in skeletal muscle, pseudoradicular irritation was established as a relevant factor for the onset of pain during walking. The present study investigates the influence of the macrocirculation on hyperalgesia at rest in intermittent claudication. In 35 patients with chronic obliterating arteriopathy of the lower limbs (stage II according to Fontaine) the ankle/arm index of arterial pressure and the walking tolerance, as well as the pain at rest on applying pressure to the calf muscles were determined before and 3 weeks after percutaneous transluminar angioplasty (PTA). All 3 parameters improved after dilatation. Improved macrocirculation leads not only to a decreased production and improved clearance of pain-inducing metabolites in muscle tissue, but also--through a decrease of sympathetic stimulation of the muscle--to an elevation of the pain threshold. Apart from the reduction in pain-inducing metabolites, an absence of booster effects on pseudoradicular irritation and the regeneration of sensitive cutaneous afferents with resultant inhibition of reflex pain development are considered as possible factors in the achievement of pain relief following PTA.

Angioplasty, Balloon↗

Enhancement of the antiemetic action of metoclopramide against cisplatin-induced emesis by transdermal electrical nerve stimulation.

In a double-blind sequential trial, the influence of transdermal electrical nerve stimulation (TENS) was studied in patients who were treated with total infusions of metoclopramide 3.5 mg/kg to counter the emetic action of cisplatin 60-90 mg/m2. Transdermal electrical nerve stimulation further reduced the emetic episodes in ten of 11 treatment pairs (2 alpha = .10). This effect was blocked by naloxone. More surprisingly, TENS reduced the incidence of extrapyramidal effects of metoclopramide (i.e., akathisia and dystonia). These effects may be explained by the involvement of central nervous and peripheral TENS-induced production of opioid neuromodulators. An alternate hypothesis is the stimulation of serotonergic mechanisms via neuromodulation by opioid peptides, or by involvement of both systems.

Adult↗

[Clinical course and pathophysiology of hyperthermia].

In 221 hyperthermic baths with 138 healthy volunteers thermoregulatory, circulatory, respiratory, renal, hematological, immunological, and endocrinological function values and sudomotoric activity have been determined. The endocrinological investigations demonstrate an increased glucocorticoidal activity (eosinopenia, T-lymphocytopenia) while plasmatic cortisole concentrations are slightly decreased. This discrepancy may be explained by an increased dissociation of biologically active cortisole and transcortin and by a more rapid activation of the steroid-receptor complex within the endocrine target cell. During a series of ten hyperthermic baths on ten consecutive days mineralocorticoidal activity during hyperthermia is increased (sudomotor activity, excretion of urine and sodium); urinary excretion of aldosterone does not change. These results indicate an increased sensitivity of the mineralocorticoidal target cell after adaptation to heat. The hypothesis can be confirmed by experiments with aldosterone i.v.

Aldosterone↗

Cardiovascular and respiratory function values in hyperthermia: the effect of beta-receptor blockade with bunitrolol.

During hyperthermia in water, the rectal temperature of 12 healthy young test subjects rose by on average 1.16 degrees C. Under treatment with placebo, the pulse rate increased by 40.6 beats/min, systolic pressure by 14.6 mm Hg, oscillatory respiratory resistance fell by 0.29 hPa/1/s and time-averaged flow ventilation increased by 3.62 1/min. Under treatment with a beta-receptor blocker (10 mg of bunitrolol) there was no change in the tachycardiac response, there was slightly less of a rise of blood pressure, slightly less of a fall of oscillatory respiratory resistance and time-averaged flow ventilation remained low (2p less than 0.05). The response of the cardiovascular parameters and oscillatory respiratory resistance is discussed in connection with redistributions of blood volume during hyperthermia. The less pronounced hyperventilation is considered to be due to the effect of beta-receptor blockade in warding off external stress-induced factors.

Adult↗

[Tissue damage following paravenous cytostatic drug application. An additional treatment with percutaneous electric nerve stimulation].

Some aspects in the development of severe tissue damage after an adriamycin extravasation are considered as a sympathetic reflex dystrophy syndrome. In this, a peripheral stimulus (e.g. pain) activates efferent autonomic and motor nerves resulting in vasomotor changes and other "dystrophic" changes in soft tissues. A typical state is the Sudeck's dystrophy syndrome. With a transcutaneous electrical nerve stimulation it should be possible to interrupt this vicious circle. A case with a good clinical result is reported.

Aged↗