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Biomedical subjects

M B Shvyrkov

Publications and source records attributed to M B Shvyrkov.

At least 19 recordsLinked to original sources
PubMed2005

[Elimination of mandibular defects with dosed distraction. Part III. Use of dosed distraction for restricted osteoplasty in subtotal and end defects of the mandible].

Two variants (3(rd) and 4(th)) of non-free mandible osteoplasty with the use of compression-distraction apparatus (CDA) elaborated during the war in Afghanistan are described by the author. The 3(rd) variant was used in cases of vast combined defects of lower part of the face when two-sided osteotomy of both mandible stumps in order to create mobile mandible fragments of the length of 2.5 cm and their follow-up shift to the middle line of the face with the help of CDA is made. Distraction of callosity and soft tissues stimulated histogenesis that led to substitution of big osseous-soft tissue defect of lower part of the face. The 4(th) variant had two stages: 1(st) stage resulted in reconstruction of mandible branch, the 2(nd) -- in reconstruction of mandible head. In such a way the new temporomandibular joint using own tissues of the patient was created without application of allotransplant or titanium explant.

Afghanistan↗
PubMed2004

[Repair of mandibular defects by dosed distraction. Part I. Distraction of the callus for osteoplasty of the mandible by local tissues].

During the war in Afghanistan the author repaired gunshot defects in the mandible using a compression-distraction device (CDD) which he designed in cooperation with A. Kh. Shamsudinov. Osteoplasty of the mandible is based on the distraction osteogenesis phenomenon. Proceeding from this phenomenon, the author developed several variants of mandibular osteoplasty in 1982-1983, one of these variants being osteoplasty with local tissues, permitting bloodless repair of mandibular defects of up to 5 cm long. Osteoplasty with local tissues can be used not only for repair of mandibular defects of any origin, but for enlarging the mandible in congenital or acquired abnormalities as well.

Bony Callus↗
PubMed2004

[Repair of mandibular defects using dosed distraction. Part II. Bound osteoplasty of the mandible by distraction osteogenesis].

Five variants of bound osteoplasty based on the distraction osteogenesis phenomenon were developed by the author for the treatment of patients with gunshot mandibular defects during the war in Afghanistan. Three of these variants are described in this paper; indications for their use and the technique of operation are presented. In fact, bound osteoplasty for gunshot wounds is primary early osteoplasty of the mandible -- the target of several generations of maxillofacial surgeons.

Humans↗
PubMed2002

[Morphogenic processes in dosed distraction].

Dosed distraction of bone regenerate is paralleled by distraction of soft tissues (skin, muscles, nerves, etc.), which is particularly obvious during liquidation of medium-sized and extensive mandibular defects. Such distraction of soft tissues leads to their regeneration and growth. However regeneration of soft tissues is paralleled by dystrophic processes, which are never observed in bone regenerate. Dosed distraction can be used in repair of combined bone and soft tissue defects and deformations of the face of different etiology.

Bone Morphogenetic Proteins↗
PubMed2001

[Primary surgical treatment of gunshot wounds of facial skeleton].

The author criticizes the traditional strategy of sparing treatment of gunshot wounds of the face involving the bones, formulated as long ago as in 1943, and suggests radical primary surgical treatment of such wounds. The author used such treatment with good results during 4 years in Afghanistan war.

Afghanistan↗
PubMed1999

Non-free osteoplasty of the mandible in maxillofacial gunshot wounds: mandibular reconstruction by compression-osteodistraction.

We have treated 33 young men with medium to large (3-8 cm) bony and soft tissue defects of the lower third of the face caused by gunshot wounds. After debridement, collapsing the proximal segments for primary approximation of soft and hard tissues and a closed osteotomy of a small fragment of mandible, we used an original compression-distraction device, designed in 1982 and tested during 1983 (analogous devices were absent at that time) to reposition the mandible and cause callus to form (during distraction) between the fragment and to use the remaining stumps of bone to fill in the defect. The soft tissues were repaired at the same time. Twenty-eight of the patients presented within a few hours of injury, and the remaining five had old injuries. The only complications were in the group with old injuries where four patients developed abscesses that required drainage, but these did not interfere with the process of osteogenesis. All 33 patients had good functional and aesthetic results within 3-4.5 months. The method allows a bloodless minimally traumatic procedure which can be carried out in one stage. The results compare very favourably with the classic methods of the treatment of mandibular gunshot injuries.

Adult↗
PubMed1998

[Experience in conducting course exams in test form].

Examinations including tasks presented as tests were carried out in 319 fourth-year students of dental surgery. This method for assessing the knowledge and skills of students proved to be highly objective.

Dentistry, Operative↗
PubMed1995

Osteoplasty of the mandible by local tissues.

Thirty three patients with 0.5 to 4.5 cm gunshot defects of the mandible were treated. The ends of the fragments of the bone were initially compressed, then distracted with the help of a compression-distraction device. The immature callus was distracted at a rate of 0.25 mm four times a day. During the process of distraction the defects of bone and soft tissues are replaced. Lack of soft tissue, which make insertion of a free bone graft impossible, is the main indication for an osteoplasty by local tissues.

Bone Lengthening↗
PubMed1987

[Effect of acid metabolites on the osteoinductive activity of the bone matrix].

The osteoinductive activity of bone matrix demineralized in acid metabolites of glycolysis and Krebs cycle have been studied in rats. The highest osteoinductive effect was reached during the demineralization in oxaloacetic acid, the lowest one--in the malic acid. The regulatory role of glycolysis metabolites and Krebs Cycle in posttraumatic osteogenesis is under discussion.

Animals↗
PubMed1982

[Simultaneous measurement of radioactivity of 45Ca and 32P in tissues using a liquid scintillator and gas-discharge counter with a filter].

Optimal conditions are developed for two methods of simultaneous recording of 45Ca and 32P-radiation in the bone and other tissues. Both methods are compared from the standpoint of their efficiency. The calculation method for the 32P hard beta-radiation in the presence of 45Ca in one tissue specimen by the liquid scintillation counter is 5-10 times as efficient as that by the gas-discharge counter with the filter. The method for recording the low-energy 45Ca beta-radiation in the combination with 32P in one tissue specimen by the end-window gas-discharge counter and filter is more efficient to some extent that the calculation in the liquid scintillation counter.

Carbon Radioisotopes↗