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Biomedical subjects

M Auriol

Publications and source records attributed to M Auriol.

At least 127 records · Page 7Linked to original sources
PubMed1985

[Proprioceptive sensitivity and orofacial functions].

Proprioceptive sensibility from stimulation of muscle, ligament articular and vestibular receptors plays a determining role in the regulation of tone, of the resting position of the mandible, of head posture and of the closure pathway of the mandible. Studies conducted on temporomandibular joints of fetuses and adult subjects failed to demonstrate the specialized corpuscles (a fact previously noted by Ramfjord) in the temporomaxillary joint capsule, described typically in other joints. In contrast, however, histology showed a particularly rich population of muscle receptors adjacent to this joint, this being only one of several particular characteristics.

Adult↗
PubMed1985

[Parotid sialadenosis. A histoenzymologic and ultrastructural study].

A case of sialadenosis was studied by means of several morphological methods (light microscopy with micrometric measurement, transmission and scanning electron microscopy, immunopathology, histoenzymology). In that disease, these investigations seem to corroborate the hypothesis of a dyscrinism, true perturbation of the salivary excretion with storage of secretory granules in the cells and consecutive hypertrophy. This dyscrinism should result from a deterioration of branches of autonomic nervous system. In the case reported here, no etiology was proved but the hypothetic part of a recent antiulcerous treatment by Tagamet was suggested.

Adult↗
PubMed1985

[Primary malignant tumors of the heart. Anatomo-clinical study of 12 cases].

Five of the 12 cardiac sarcomas reviewed in this study were recruited from 7,200 autopsy studies, including 2,980 performed on patients dying from malignant disease (overall incidence of 0.07 p. 100; 0.16 p. 100 in the group with malignant disease). These tumours are fifty times less common than cardiac metastases which were observed in 12.5 p. 100 of patients in the group with malignant disease. The other 7 cases of cardiac sarcoma were recovered from our surgical pathology archives over a 16 years period. The sarcomas were of the following histological types: angiosarcoma (6 cases), rhabdomyosarcoma (3 cases), fibrosarcoma (2 cases) and mesothelioma (1 case). The clinical presentation was very variable. The diagnosis was often made only at surgery or autopsy. The prognosis was very poor, the majority of patients dying of cardiac constriction or visceral metastases, within one year of diagnosis.

Adult↗
PubMed1984

Histoenzymological and ultrastructural study of a bifocal calcifying epithelial odontogenic tumor. Characteristics of epithelial cells and histogenesis of amyloid-like material.

A calcifying epithelial odontogenic tumor, simultaneously located in the two jaws (maxilla and mandible) was examined by histochemical and electron microscopic methods. Squamous tumor cells without secretory polarity were different from those of common ameloblastoma. High activities of alkaline phosphatase and ATPases were demonstrated by light and electron microscopy on the cytoplasmic membrane, findings similar to those in the stratum intermedium cells of the normal dental germ from which these tumor cells seem to arise. The tumor cells, like preameloblasts of the dental germ, also produce a granulo-filamentous material in intracytoplasmic vesicles and discharge it into the stroma. This "pseudo-amyloid" substance represents an abnormal protein of the enamel matrix and calcification, mainly occurring in that substance, might be an attempt at mineralization.

Adenosine Triphosphatases↗
PubMed1984

Iodine-induced thyrotoxicosis: analysis of eighty-five consecutive cases.

Iodine-induced thyrotoxicosis was documented in eighty-five cases. Eighty per cent occur in apparently normal thyroid glands; 60% among them occur in males. Amiodarone accounted for 50% of iodine-induced thyrotoxicosis. Mean thyroid hormone levels at diagnosis were: FT1: 21.7 (normal mean: 7.5, arbitrary units); T3: 4.53 nmol 1(-1) (normal: 2.30 nmol 1(-1). Mean 131I- 24-h uptake was 3.5% (normal range in France 25-45%) and was activated by exogenous TSH (mean 27%). The spontaneous cure in nontreated cases was observed within an average 6 months. A phase of biological hypothyroidism (mean FT1: 3.7, T3: 1.23 nmol 1(-1), TSH: 9.6 microU ml-1 (normal TSH range: 1-7 microU ml-1] preceded the return to euthyroidism. Intrathyroid iodine content measured by X-ray fluorescence was high, then fell gradually. Thyroid tissue study showed a large quantity of intrathyroid iodine and the overiodination of thyroglobulin. Histological and electron microscopic studies are reported. Prednisone and in some cases propylthiouracile were found to be effective.

Adolescent↗
PubMed1984

Histoenzymological features of epithelial cells in epidermoid carcinomas of oral mucosa and in ameloblastomas of jaws.

An histoenzymological study comprising oxidative enzymes, diaphorases, acid and alkaline phosphatases, naphtolesterases, referred to 60 biopsy and operation specimens. It showed interesting arguments for diagnosis and understanding of precancerous and cancerous lesions of the oral mucosa and also of ameloblastomas of jaws. The enzymatic activities of precancerous and cancerous oral lesions were compared with those of normal buccal mucosa and epidermis, benign hyperkeratosis (activities similar to those of the epidermis) and lichen planus. In severe dysplasia and epidermoid carcinoma, numerous variations of oxidative, esterase and acid phosphatase activities were seen from one cell to another. But this pattern was non conclusive for the diagnosis, a similar one being found in inflammatory lesions and especially in the lichen planus. In lobules of invasive carcinoma, the strong enzymological activities (particularly acid phosphatases, naphtolesterases) were correlated with a high degree of differentiation of the tumor and these enzymatic methods offered an interesting contribution for the fine evaluation of histoprognosis in malignant epithelial tumors. Among the lesions of jaws, radicular and dentigerous cysts had low enzymatic activities similar to those of normal buccal epithelium. The epidermoid cysts (keratocysts), because of their highly differentiated keratinization, like benign hyperkeratosis, had the same enzymatic activities as epidermis. Peculiar were the enzymatic activities of common ameloblastoma; they differed from those of other lesions of squamous tissues (low oxidative activities without decreasing gradient). Besides, round epithelial clumps, the stroma showed a high and widespread alkaline phosphatase activity. Thus, this peculiar stromal activity may be useful to differentiate ameloblastoma from the other epidermoid cysts of the jaws. In the other hand, such a constatation suggests a low degree of odontogenic induction.

Ameloblastoma↗
PubMed1984

[Visceral scleroderma].

Visceral involvement in systemic scleroderma is frequent, the most commonly affected organs being the kidney, the lung, the heart and the gastro-intestinal tract; associating different degrees of sclerosis and vasculitis depending on which organ is involved. However, this is not always clinically obvious, and angiospastic phenomena may be assumed to be responsible for certain ischaemic lesions. The diagnosis is also difficult because some visceral lesions may occur at an early stage and appear to be of primary origin. Extensive investigation, including biopsies to demonstrate small vascular changes then becomes essential.

Digestive System Diseases↗
PubMed1984

[Hemangiopericytoma of the orofacial region].

Prognosis in 11 cases of hemangiopericytoma of the orofacial region (9 buccal and 2 parotid tumors) was, as with these lesions in other zones, an uncertain entity: 4 local recurrences within 8 months to 7 years; one fatal outcome after 3 years from pulmonary micrometastases. Histologic classification of these tumors into 3 cytologic groups of increasing malignancy (I to III) is a function of the number of their cytologic anomalies. They are also divided according to their overall morphology into poorly differentiated, differentiated and sclerous types. Positive correlations between structure and cytologic criteria of malignancy and structure and clinical course have been demonstrated. Ultrastructural examination in 2 cases showed polymorphic endothelial, fibroblastic and smooth muscle cells in contact with adult tumoral pericytes. This suggests the origin of the tumor from young cells of multiple potency rather than from adult pericytes.

Adolescent↗