Biomedical subjects
M Armengot
Publications and source records attributed to M Armengot.
Prognostic value of histopathological parameters in 51 supraglottic squamous cell carcinomas.
The prognosis for supraglottic squamous cell carcinomas is difficult to establish. A study of 19 histopathological parameters (14 from the primary tumor and 5 from the lymph node metastases) was undertaken in 51 supraglottic epidermoid carcinomas. All patients were subjected to supraglottic horizontal laryngectomy with bilateral functional neck dissection and postoperative radiotherapy. A discriminant analysis was performed to relate the different histopathological variables to 5-year survival. Capsule rupture and the number of metastatic lymph nodes were the only two parameters significantly related to survival (P < .01). Histopathology (in particular, lymph node metastases) proved more effective in predicting patient evolution than TNM staging.
[The influence of age, sex and circadian rhythms on the nasal mucosal in the mucociliary clearance].
We have studied the nasal mucociliary transport in 115 normal persons between 5 and 85-years-old. Using vegetable charcoal powder method the transport time varies between 5 and 18 minutes. The mean transport time was 8.35 +/- 2.6 min. Transport time is not variable with age until sixty years, when transport slow down. The mucociliary clearance is faster in female (p = 0.018). In these individuals the transport time is less in the evening-hours (p = 0.01). In men no differences has been noted (p = 0.57).
[Kniest syndrome. An audiological study].
In this syndrome there is a disproportionate dwarfism with kyphoscoliosis, stiffness of the joints, minor facial dysmorphia, myopia and both conductive and sensorineural deafness in 50 percent of patients. It is a dominant autosomic heritable malady of unknown incidence, but both sexes seems equally affected. The patient's condition is diagnosed at birth, because of the short limbs and the enlargement of the joints. In the presented case, diagnosed at birth, the deafness was suppose to be transmissive, owing to the coexistence of a cleft palate, and consequently a grommet was inserted in the tympanum. Only afterwards, when the girl was 12 years old, the cochlear component of the hypoacusis fell in consideration.
[Granular cell tumor (Abrikossoff's tumor). A review and our experience].
The low incidence of these tumors compelled the AA., after diagnosis of one of laryngeal sitting, to a review of the theme and its literature as well, particularly under the viewpoint of its histogenesis, which has been debatable up to lately. The report is complemented with the study of immunohistochemical tests for NHK, S-100 and specific neural enolase of the specimen.
[Prognostic value of histopathological parameters in epidermoid carcinoma of the vocal cords in T-1 stage].
In this paper are studied macro- and microscopically, 14 histopathologic parameters belonging to 37 patients suffering from vocal cord squamous cell carcinoma, stage T-la. All patients were submitted to cordectomy and followed up during a 5 years term, as a minimum. A discriminant analysis was performed in order to establish the relation between histopathologic parameters and local failure. Only two of them were statistically significative (p < 0.01): the structural type and the differential degree of tumor cells. The histopathological study allowed the prediction of 82 percent of local recurrences.
Nasal mucociliary function in the normal newborn.
Nasal mucociliary transport has been studied using the seroalbumin-Tc99m radioisotope method in 10 adults and 10 normal newborns under 28 days of age. The mean transport velocity was 8 and 6 mm/min for the normal adults and newborns, respectively, with no significant differences between the two (P = 0.07).
Cholesteatoma in children: results in open versus closed techniques.
Cholesteatoma in children presents characteristics that differentiate it from the adult condition. Surgery has been performed in 55 ears. The main reason for referral was otorrhoea (83 per cent), either alone (29 per cent) or with hearing loss (54 per cent). Apart from three cases with an intact eardrum, a perforation was always present mostly posterior-superior (50 per cent). Open techniques were performed in 27.3 per cent of the ears and the closed technique in 72.7 per cent. Only in 18 per cent of cases was the ossicular chain normal and mobile. The attic was occupied by cholesteatoma in 79 per cent. Recurrence took place in 37 per cent and 13 per cent of the closed and open techniques respectively. Open techniques tend to be employed in the presence of extensive disease, whereas the closed technique is reserved for those with a more localized problem.
[Determination of the phase of synthesis by means of bromodeoxyuridine. Its clinical application in oncology of the head and neck].
Tumour cell kinetics properties studied by the bromodeoxyuridine method, are useful in the prognosis and therapeutic planning of oncologic patients. In this paper the AA. review some clinical applications of this method, with special emphasis on head and neck tumours.
[Laryngocele. Report of a case of giant laryngocele associated with occult papillary carcinoma of the thyroid].
This gross laryngocele caused a chronic obstruction of the upper respiratory airway. Diagnosis become obvious because the aggravation of a chronic bronchopathy slightly developed, which run into a cor pulmonale chronic as well. Incidentally linked with a neck metastasis spread out from a hidden papillary carcinoma of the thyroid gland. The laryngocele was treated by extramucous lateral thyrotomy and the carcinoma removed through subtotal thyroidectomy.
[Hormones and the nasal mucosa. A bibliographic review].
The development and activity of the nasal mucosa are influenced by many hormonal substances. In this work we realize a bibliographical review about the effect of adrenaline, thyroid hormones, corticosteroids and sex hormones on the nasal respiratory mucous membrane. We emphasize the clinic consequences.
Nasal mucociliary function during the menstrual cycle in healthy women.
Nasal mucociliary transport time was studied in nine healthy women over the menstrual cycle using the vegetable charcoal powder technique. Three measurements were made at different points of the cycle: during the early follicular phase, periovulatory phase and luteal phase. The mean transport times were 10.1 +/- 3.50, 5.1 +/- 2.08 and 7.5 +/- 3.28 minutes, respectively. Transit was significantly accelerated during the periovulatory phase (p less than 0.01), when the seric estrogens are at their highest level.
[Olfaction in laryngectomized patients: effect of the phonatory prosthesis].
We have studied olfaction in 20 laryngectomies, only 10 of which were supplied with phonatory prosthesis. We conclude that patients without prosthesis show a higher threshold for perception of pure olfactory stimulants, whereas in those provided with the prosthesis the pure olfactory threshold remains within normal values.
The influence of anesthetics and vasoconstrictors on nasal mucociliary transport.
Nasal mucociliary transport time is studied in 38 healthy individuals using the charcoal dust technique, following topical application of a lidocaine solution in 10 cases, tetracaine in 11, and oxymetazoline in 17. The results show that lidocaine does not alter the transit time, whereas tetracaine increases it significantly; in turn, oxymetazoline progressively increases transit time, although this slowing is fully reversible 30 minutes after application.
[Study of nasal ciliary mechanics in allergic and vasomotor rhinopathies].
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[Aggressive oral fibromatosis in children].
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[Immunologic study of the nasal mucus and secretion in chronic otitis media with closed tympanum].
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[Olfactory neuroblastoma. Review of the Spanish literature and presentation of 2 cases].
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