Ketamine anesthesia and intraocular pressure.
We studied the influence of intramuscular ketamine-narcosis on the intraocular pressure of rabbits. Tonography and indirect arterial pressure measurements were performed 5 to 10 minutes after the administration of the agent. The systolic arterial pressure did not change significantly, whereas the intraocular pressure significantly increased. The intraocular pressure increase was 7% on the average with a maximal increase of 20%. In more than half of the cases the arterial and intraocular pressures changed in the opposite directions which speaks for the role of other factors in enhancing these pressure alterations.
Anesthesia, General↗