Search PubMed⌕ Search

Biomedical subjects

M Amin

Publications and source records attributed to M Amin.

At least 145 records · Page 8Linked to original sources
PubMed1977

Terminal loop cutaneous ureterostomy: a method of urinary drainage in kidney transplantation.

A non-functional and permanently damaged lower urinary tract is no longer a contraindication to kidney transplantation. In patients with this disorder the ureter commonly is drained by an intestinal conduit. We have used terminal loop cutaneous ureterostomy as a method of urinary drainage in 3 patients with cadaver kidney transplants who have been followed for up to 8 years. The technique of terminal loop cutaneous ureterostomy and a report of these cases are presented.

Adult↗
PubMed1976

Quantitative thin-layer chromatographic analysis of ergotamine tartrate and caffeine in the nanogram range.

Direct, quantitative, thin-layer chromatographic methods for the determination of ergotamine tartrate and caffeine in the presence of each other in blood and in pharmaceutical preparations are described. The blood is centrifuged, the plasma decanted from the coagulum and deproteinized with acetone-methanol. After removal of the solvent mixture, the active ingredients are extracted from the remaining aqueous solution with chloroform. In the case of the pharmaceutical preparations, the active ingredients are also extracted with chloroform or methanol. Ergotamine tartrate and caffeine are separated on pre-coated silica gel 60 F254 plates and measured directly on the thin-layer plate, ergotamine tartrate being determined by the fluorescence method, excitation wavelength 365 nm, at lambdamax.=450 nm and caffeine by the reflactance method at lambdamax.=274 nm. The analytical methods are suitable for the bioavailability studies of these drugs in blood as they enable the determination of 20 ng ergotamine tartrate with a coefficient of variation of 6.7% and the determination of 200 ng caffeine with a coefficient of variation of 6.1%. The methods have also proved useful in the determination of the active ingredients of drug forms such as tablets and suppositories and can be well reproduced with a maximum coefficient of variation of 4.9% for ergotamine tartrate and 3.5% for caffeine.

Biological Availability↗
PubMed1976

Non-deflating Foley catheter.

The different methods of removal of a non-deflating ureteral catheter were compared with the stylet technique. Two hundred and sixty randomly selected catheters were tested. Overdistention of the balloon with water or air and chemically induced rupture of the balloon produced fragments of various sizes in almost 100%. Our stylet technique failed to demonstrate any of the complications reported in the literature i.e., chemical or mechanical injury to the bladder or retained rubber fragments causing stone formation.

Humans↗
PubMed1976

Renal fascia of Gerota.

There are controversial views regarding the configuration of the renal fascia of Gerota. Various arrangements described in the literature are presented. A consensus is derived and its clinical importance stressed.

Fascia↗
PubMed1976

Urologic complications following abdominoperineal resection.

In a retrospective study we analyzed the high incidence of 75 urological complications after abdominoperineal resection in 52 patients. A prospective study was done also to anticipate as well as to minimize or eliminate these highly significant complications. Direct injury leading to obstruction and fistula formation was avoided. Obstructive uropathy in 10 of 25 male patients was found as a direct result of preoperative evaluation. Same day prostatectomies in 5 patients made no appreciable difference in the urological management, complication rate or end results. Neurogenic bladder dysfunction of various degrees was found in 50 per cent of all patients but represented a long-term problem in only 10 per cent.

Abdomen↗
PubMed1976

Gunshot wounds to the ureter.

Since our last review 17 more patients have been treated for ureteral gunshot injuries. In six cases the upper ureter, in two the middle, and in nine cases the lower ureter was involved. Associated visceral injuries were numerous with the small intestine the most commonly injured. In over 50% of the injuries to the lower ureter, the iliac vein was injured. In three patients the ureter was the only major structure involved. There was no hospital mortality. Optimal surgical repair done by generous resection, primary end-to-end anastomosis and stenting and drainage via a proximal ureteral T-tube gave excellent results and no longterm complications in a population subject to careful short and longterm followup. While an uncommon injury, the principles of effective repair are clear and must be applied in the face of serious associated disorders to continue these satisfactory results.

Abdominal Injuries↗
PubMed1976

[Comparative studies in man on the percutaneous absorption of diflucortolone valerate, betamethasone-17-valerate, beclomethasone dipropionate and fluocinolone acetonide].

Percutaneous absorption of 6alpha,9-difluor-11beta-hydroxy-16alpha-methyl-21-valeryloxy-1,4-pregnadience-3,20-dione (diflucortolone valerate, DFV, Nerisona), betamethasone 17-valerate (BV), beclomethasone dipropionate (BDP) and fluocinolone acetonide (FA) by damaged skin was examined on the backs of 4 healthy males from whom the stratum corneum had been removed by "stripping". The determination of percutaneous absorption was performed on the one hand by a method employing radioactive labelled compounds (DFV, BV) and measuring the elimination with the urine and faeces and on the other hand by photometric determination (DFV, BV, BD, fa) of the corticoid remaining on the skin immediately following application and at the end of a 24-h period of exposure. Direct measurement of the radioactivity in the urine and faeces revealed that percutaneous absorption from a new W/O emulsion takes place up to 2.2+/-0.8% in the case of DFV (0.1%) and to at least 12.2+/-3.3% in the case of BV (0.12%) within 24 h. The determination of percutaneous absorption via recovery from the skin produced the following results for the 4 corticoid preparations examined: DFV (14.8+/-4.2%) and BDP (14.0+/-4.3%) approximately equal, BV (23.5+/-4.1%) a marked increase and FA (39.2+/-2.4%) the highest level of absorption. This order for percutaneous absorption appears to correlate to the frequency of systemic side effects.

Administration, Topical↗
PubMed1976

Terminal loop cutaneous ureterostomy: a method of urinary drainage in kidney transplantation.

A non-functional and permanently damaged lower urinary tract is no longer a contraindication to kidney transplantation. In patients with this disorder the ureter commonly is drained by an intestinal conduit. We have used terminal loop cutaneous ureterostomy as a method of urinary drainage in 3 patients with cadaver kidney transplants who have been followed for up to 8 years. The technique of terminal loop cutaneous ureterostomy and a report of these cases are presented.

Abdominal Muscles↗
PubMed1975

Direct quantitative thin-layer chromatographic determination of prostaglandins A2, B2, E2 and F2 alpha.

A direct method for the determination of prostaglandins (PG) A2, B2, E2 and F2 alpha by thin-layer chromatography (TLC) is described. The TLC development is carried out on silica gel 60 F254 plates so that PGA2, PGB2 and PGE2 can be directly determined together by chromatogram spectrodensitometry using the reflection method. PGE2 must be converted into pgb2 so that it can be measured at lambda max. 224 nm and after conversion into PGB2 by spraying with potassium hydroxide solution. PGF2 alpha is measured after spraying with methanolic sulphuric acid and subsequent heating at lambda max. 530 nm. The method of determination described here is characterized by a short analysis time and good accuracy, and it is therefore suitable for quality control and stability investigations with these prostaglandins. The coefficient of variation is plus or minus 3.5 percent.

Chromatography, Thin Layer↗
PubMed1975

Traveling bullets in genitourinary tract.

A bullet lodged in the renal parenchyma, then migrated into the collecting system over a two-month period causing acute renal colic and necessitating removal by pyelotomy. A review of the literature discloses only 8 cases of projectiles migrating in the urinary tract, 5 involving metallic fragments and 3 involving bullets.

Adult↗
PubMed1975

Blastomycosis of the genitourinary tract.

In a retrospective study of 51 cases of systemic North American blastomycosis 11 patients were found to have genitourinary tract involvement, the prostate and epididymis being most commonly affected. Diagnosis was made by culture of the fungus from urine, abscess or prostate secretions, morphologic identification of the characteristic organism in urine or secretions, or histologic examination of tissue specimens. Treatment with amphotericin B reduced the mortality rate of 90 per cent to as low as 10 per cent. Long-term followup is necessary because of a relapse rate of 10 to 15 per cent.

Adult↗
PubMed1974

An approach to the current-voltage characteristics of nerve membranes based on adsorption phenomena.

Using Stern's double-layer adsorption model for the density of cations in the membrane pores, a quantitative approach to the stationary current-voltage characteristic of nerve membranes is developed. The interaction of mobile cations with the negative fixed charges, located inside the membrane, constitutes a resistance for the current through the membrane. The stepwise increase in the resistance for the hyperpolarization is ascribed to a stronger interaction accompanying a depletion of the adsorbed cations from the interior. Thermodynamic treatment of flows and forces is adapted to the situation, to give a current voltage relation amenable to experimental check. The value of the resting potential thus obtained gives a deviation from Nernst equation applied to the ion for which the membrane is mainly permeable. The effect of the membrane double-layer potential on the potential range in which the transition from low to high resistance takes place, is explicitly incorporated. Finally, a comparison of the theory with the experimental results for the squid axon and frog nerve fibers is made.

Animals↗