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Biomedical subjects

M Altini

Publications and source records attributed to M Altini.

65 records · Page 4Linked to original sources

Basal cell extensions in human oral mucosa.

Basal cell extensions have frequently been observed in a variety of odontogenic lesions as well as in the fibrous epulis (fibrous hyperplasia of the gingiva). In order to determine the frequency of these extensions in normal human oral nucosa, a study using autopsy and surgical material was conducted. The results indicated that a specific type of rete ridge morphology exists for gingiva, including the presence of thin double stranded extensions which may be related to the functional role of the gingiva or to the fact that the odontogenic apparatus is derived from surface epithelium in this region in the developing embryo, or both. Similar extensions have not been found in other oral epithelia.

Gingiva↗

A case report of keratoameloblastoma.

In the "WHO histological typing of odontogenic tumors, jaw cysts and allied lesions", the authors recognize five distinct histologic types of ameloblastoma. A further histologic variant, the keratoameloblastoma, was first described by PINDBORG. A second case of a keratoameloblastoma is reported. This lesion occurred in the maxilla of a 28-year-old Caucasian male.

Adult↗

Ameloblastic dentinosarcoma- a case report.

A rare case of ameloblastic dentinosarcoma is reported. The literature regarding ameloblastic fibro- and odontosarcomas is reviewed. There have been 16 reported cases of ameloblastic fibrosarcoma and another six cases (one uncertain) of ameloblastic fibrosarcoma which showed induction of dentin or enamel and which therefore according to the WHO Classification should be separately classified as ameloblastic odontosarcomas. Our case showed no enamel and therefore is better called ameloblastic dentinosarcoma. Ameloblastic sarcomas of the jaws are of low grade malignancy, do not often metastasize, and if treated by radical resection have a good prognosis.

Adult↗

Granular cell peripheral odontogenic fibroma.

A case of a peripheral odontogenic fibroma which contained aggregates of large granular cells is reported. These granular cells are similar to those previously described in the granular cell myoblastoma, congenital epulis and the granular cell ameloblastic fibroma. Deep extensions of the basal layer of overlying gingival epithelium, in double-strand fashion, are frequently observed in peripheral odontogenic fibromas. These strands closely resemble those seen in the tumor itself. On this basis, and as similar basal cell prolongations are seen in otherjaw lesions, it is postulated that residual ectomesenchymal influence may be responsible for inducing the basal cell proliferations in a similar manner to that which occurs during early embryonic dental development. This, it is suggested, might possibly be the histogenesis of the odontogenic epithelial strands in the peripheral odontogenic fibroma.

Adult↗

The calcifying odontogenic cyst. Eight new cases and a review of the literature.

Eight new cases of the calcifying odontogenic cyst have been reported. In addition, a review of the literature produced an additional sixty-five cases. This lesion can occur in any age group, but it shows a peak incidence in the second decade. It is evenly distributed between the maxilla and the manidible and occurs with equal frequency in males and females. There does not appear to be any race predilection. The calcifying odontogenic cyst may occur in association with other pathologic entities. It is postulated that it does not in every case represent a separate pathologic entity but that it may represent a secondary phenomenon which occurs within preexisting lesions.

Adult↗

Gigantiform cementoma of the jaws.

Fibro-osseous cemental lesions of the jaw remain a controversial area of bone/cementum pathology. This article describes the clinicopathological features of 28 lesions classified as gigantiform cementoma. Black women are affected more frequently than other race and sex groups, with a peak frequency of occurrence in the fourth and fifth decades. The posterior mandible is preferentially affected and unifocal lesions (67.9%) occur more frequently than multifocal lesions (32.1%). Dull pain and a centrifugal size increase are the most prevalent presenting symptoms. Of 28 cases with parental and sibling clinical information, there were no cases which exhibited an autosomal dominant genetic association. The pathogenesis of this lesion in relation to other cemental lesions of the jaws, as well as the clinical management of cemental jaw lesions, is discussed.

Adult↗