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Biomedical subjects

M A Jenike

Publications and source records attributed to M A Jenike.

At least 145 records · Page 8Linked to original sources
PubMed1984

The EEG in obsessive-compulsive disorder.

Of 12 patients with severe obsessive-compulsive disorder, one third had EEG abnormalities over the temporal lobes. Each of these patients was given a trial of anti-seizure medication; only 1 improved.

Adult↗
PubMed1984

Trazodone-digoxin interaction in an animal model.

Serum digoxin concentrations have been reported to increase in two patients taking daily doses of trazodone. However, in a canine model, no elevation in serum digoxin concentration was found with combined trazodone-digoxin administration. The authors suggest that serum digoxin concentrations should be monitored in patients receiving trazodone and digoxin concomitantly.

Animals↗
PubMed1983

Tardive dyskinesia: special risk in the elderly.

Tardive dyskinesia has emerged as a considerable public health hazard. In view of the overwhelming evidence that the elderly are particularly susceptible to this complication of neuroleptic use and the fact that there is no really effective treatment, neuroleptics should be avoided whenever possible in elderly patients.

Adult↗
PubMed1983

Monoamine oxidase inhibitors in obsessive-compulsive disorder.

The authors describe the use of monoamine oxidase inhibitors (MAOIs) in eight patients with severe obsessive-compulsive disorder. In four cases, the MAOIs produced rapid and sustained remission of symptoms; no response was seen in four other patients. All patients who responded to MAOIs, but none of the nonresponders, had phobic anxiety and/or panic attacks. Thus, a trial of MAOIs is indicated in obsessive-compulsive disorder, especially when phobic anxiety or panic attacks form part of the clinical picture.

Adult↗
PubMed1982

Cimetidine in elderly patients: review of uses and risks.

Cimetidine is widely prescribed but has numerous potential side effects, especially in elder patients, who require a lower dosage, e.g., 300 mg twice daily. Antacids may be more effective than cimetidine in preventing acute gastrointestinal bleeding in critically ill elderly patients. Cimetidine increases the risk of toxicity of other commonly used drugs such as phenytoin, diazepam, chlordiazepoxide, propranolol, theophylline, warfarin, and carbamazepine. Elderly patients taking cimetidine are at risk for neuropsychiatric changes, which may be temporarily reversed by physostigmine. Other side effects and indications for use are reviewed.

Administration, Oral↗