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Biomedical subjects

M A Jenike

Publications and source records attributed to M A Jenike.

At least 127 records · Page 7Linked to original sources
PubMed1986

Concomitant obsessive-compulsive disorder and schizotypal personality disorder.

Despite advances in the management of patients with obsessive-compulsive disorder, some remain refractory to treatment. The authors retrospectively examined characteristics of 43 treatment-resistant obsessive-compulsive patients and found that those with concomitant schizotypal personality disorder had an extremely high rate of treatment failure. Of the 29 treated nonschizotypal patients, 26 (90%) improved at least moderately; only one of 14 (7%) schizotypal patients improved. In addition, the number of schizotypal features in each patient was strongly negatively correlated with treatment outcome.

Adolescent↗
PubMed1986

Combination therapy with lecithin and ergoloid mesylates for Alzheimer's disease.

A 10-week placebo-controlled double-blind crossover protocol of combination therapy with lecithin and ergoloid mesylates was conducted in seven patients with presenile and senile dementia, Alzheimer's type. The patients' abilities to detect spatial arrangements, to recognize faces, and to identify new words on the Delayed Recognition Span Test were not significantly improved. Dementia Rating Scale scores before treatment were not significantly different from those after treatment.

Aged↗
PubMed1986

MMPI correlates of obsessive-compulsive disorder.

The MMPI was administered to 32 patients with pure obsessive-compulsive disorder. Twelve of the patients had been previously misdiagnosed as having schizophrenia, 10 had been treated with neuroleptics, and 1 developed severe tardive dyskinesia. An MMPI profile for obsessive-compulsive disorder is described.

Diagnosis, Differential↗
PubMed1985

The impact of grief on ventilatory control.

The authors studied ventilatory control in four parents grieving over the death of an infant. Abnormalities in respiratory control were common and resembled those previously reported in depressed patients. The results raise questions about the relationship between affective state and ventilatory control.

Adult↗
PubMed1985

Dysmorphophobia.

Explore the source record for details and available documents.

Adult↗
PubMed1985

Erythema multiforme associated with trazodone therapy: case report.

A 63-year-old woman with treatment-resistant depression was started on trazodone and subsequently developed erythema multiforme (EM), with lesions predominant on the distal parts of the limbs and involvement of the hands and feet, as well as her palms and soles. The patient's treatment course and subsequent remission are described. It is suggested that trazodone therapy be discontinued immediately upon notice of EM. This patient was also taking lithium, which has not been implicated in erythema multiforme.

Depressive Disorder↗
PubMed1985

Partial resolution of ranitidine-associated delirium with physostigmine: case report.

A healthy 25-year-old woman experienced probable ranitidine-induced confusion that partially resolved with intravenous physostigmine. The only known prior report of confusion associated with this relatively new agent was in a severely ill 86-year-old woman. Clinicians should be alert for mental status changes with ranitidine and consider a trial of physostigmine when indicated.

Adult↗
PubMed1984

The dexamethasone suppression test in patients with presenile and senile dementia of the Alzheimer's type.

The dexamethasone suppression test (DST) was performed on 18 patients with presenile and senile dementia of the Alzheimer's type. Objective cognitive testing showed that 13 patients were mildly to moderately impaired and five were moderately to severely impaired. The Hamilton Depression Scale yielded normal results in all patients. The DST results were abnormal in only one of the mildly impaired patients but in four of the five moderately impaired patients. These data suggest that the DST may be a useful clinical tool in mildly impaired patients with Alzheimer's disease but is likely to be confounded by disease in moderately to severely impaired patients.

Aged↗
PubMed1984

The use of monoamine oxidase inhibitors in the treatment of elderly, depressed patients.

Depression is an extremely common illness in the elderly, and is, at times, refractory to the usual therapies. The elderly are also particularly prone to develop toxic side effects from standard antidepressive agents. Monoamine oxidase inhibitors are rarely used in this population, although much evidence and clinical experience would indicate that they can be extremely effective and non-toxic. This paper outlines the indications and precautions for use and side effects of monoamine oxidase inhibitors in the treatment of depression in elderly patients.

Acute Disease↗
PubMed1984

Alprazolam as treatment for a case of obsessive-compulsive disorder.

Because of the anxiety accompanying his obsessions and a prior panic attack, an obsessive-compulsive man was given alprazolam, which reduced his obsessions and eliminated his compulsions. The authors discuss links between obsessive-compulsive disorder and other psychiatric disorders.

Adult↗