Search PubMed⌕ Search

Biomedical subjects

Louis Mandel

Publications and source records attributed to Louis Mandel.

At least 19 recordsLinked to original sources
PubMed2006

False-positive xerostomia following radioactive iodine treatment: case report.

Radioactive iodine (131I), used in the treatment of differentiated thyroid carcinoma, is known to cause both short-term and long-term radiation damage to the salivary glands. The injury appears as glandular swellings and/or decreased salivation with 131I dosage and passage of time playing significant roles. A case report is presented to alert the profession to the existence of patients who have received 131I therapy and who complain shortly thereafter of xerostomia, but following a thorough examination are found to represent a group of false-positives. Emphasis is placed on the diagnostic techniques used in the differential diagnosis.

Adult↗
PubMed2006

Bilateral temporalis muscle hypertrophy: a case report.

Although masseteric hypertrophy is common and can be accompanied by temporalis hypertrophy, temporalis hypertrophy by itself is an exceptional finding. A patient, a chronic bruxer who was receiving psychiatric care and psychotherapeutic medications, complained of moderate discomfort and swelling in both temporal areas. It is believed that the patient's long-term stress-related sleeping problem was causing her bruxism. Of great interest was the fact that chronic bruxing had resulted in the rare occurrence of temporalis muscle hypertrophy without a coexisting masseteric hypertrophy.

Adult↗
PubMed2006

An unusual pattern of dental damage with salivary gland aplasia.

BACKGROUND: Dental destruction can develop from numerous causes. Major salivary gland aplasia is an uncommon causative factor. The resulting xerostomia can lead to extensive dental demineralization. CASE DESCRIPTION: The author examined a 19-year-old man because of the patient's concern regarding decreased salivary volume and his dental condition. There was extensive loss of tooth structure and an astonishing pattern of dental destruction most notable on the palatal portions of the maxillary molars and premolars that is best described as "chipping." It was only after taking the patient's history, clinically examining the patient and conducting a radioisotope study that the author was able to make a confident diagnosis of the absence of four major salivary glands. CLINICAL IMPLICATIONS: Dentists should be aware that salivary gland aplasia is an uncommon cause of dental deterioration. It may manifest itself not by extensive caries but by a dental chipping effect. Early recognition and a therapeutic strategy can prevent progressive dental damage.

Adult↗
PubMed2006

Diagnosing bulimia nervosa with parotid swelling. Case report.

Patients with bulimia nervosa (BN) may show dental erosion, resulting from the effect of acid regurgitation. Asymptomatic bilateral parotid swellings may also be present. Other signs include serum electrolyte imbalance and Russell's sign. The authors describe the case of a 26-year-old woman with BN, whose only clinical manifestation of BN was her bilateral parotid swellings. Because patients with BN tend to be secretive about their purging, it is important that the clinician consider BN as part of a differential diagnosis when faced with such painless parotid gland swellings.

Adult↗
PubMed2005

Dental erosion due to wine consumption.

BACKGROUND: Dental erosions can result from numerous causes, but extrinsic dietary factors are the most common. Because of wine's acidity, it may have a deleterious effect on teeth. Its use must be considered during an evaluation of erosive dental changes. CASE DESCRIPTION: The author examined a 56-year-old woman because her referring dentist had noted extensive erosive loss of tooth structure, mainly enamel. The author eliminated the usual causes of dental erosion. It was only after a detailed history was obtained and dietary investigation was undertaken that the author determined that the amount, manner and timing of the patient's wine drinking was the cause of the problem. CLINICAL IMPLICATIONS: Dentists should be aware that wine could be a cause of dental erosion. Early recognition negates progressive dental damage with its need for extensive dental restoration. Furthermore, because patients with wine-incited dental erosions consume large volumes of wine with its significant alcohol content, medical referral by the dentist for a liver assessment is indicated.

Dental Enamel Solubility↗
PubMed2005

Treatment of refractory sarcoidal parotid gland swelling in a previously reported unresponsive case.

BACKGROUND: Sarcoidosis is a multisystem granulomatous disease that is seen occasionally in patients with characteristic bilateral parotid gland swelling. Conventional therapy has involved either no treatment because of spontaneous remission or corticosteroids when organ involvement is severe. CASE DESCRIPTION: The authors describe a previously published case report of a patient with sarcoidosis with parotid gland swellings who did not respond to standard therapy. Despite the use of various immunosuppressive agents, the swellings failed to resolve over a three-year period. It was only after a newly recommended agent, infliximab, was used that the patient's condition was treated successfully. CLINICAL IMPLICATIONS: It is important for dental practitioners to be familiar with manifestations of sarcoidosis, particularly its salivary gland aspects. Inherent in the knowledge of the disease is the therapeutic approach to both routine and recalcitrant

Adolescent↗
PubMed2005

Parotid enlargement in patient with HIV.

Patients with bilateral parotid swellings are seen in the dental office. The swellings may be initiated by HIV. Diagnosis demands a thorough clinical examination combined with imaging. Usually, multiple parotid cysts are present. However, the authors wish to call attention to those HIV patients whose swellings are caused by a lymphocytic infiltration. A case report is used to illustrate signs and symptoms.

CD8-Positive T-Lymphocytes↗
PubMed2004

Diagnosing bulimia nervosa with parotid gland swelling.

BACKGROUND: The authors describe bulimia nervosa, or BN, and its effect on the parotid gland. The associated asymptomatic bilaterally enlarged parotid glands often present a diagnostic dilemma. CASE DESCRIPTION: The authors present a case of a 22-year-old woman with BN who had bilateral parotid gland swelling, serum electrolyte alteration and no dental stigmata. Her principal concern was the associated cosmetic deformity. CLINICAL IMPLICATIONS: Because patients with BN who have parotid gland swelling usually are secretive about their purging, the diagnosis may be confirmed by conducting a clinical examination and a serum electrolyte study. Prompt diagnosis can avoid serious medical complications.

Adult↗