Search PubMed⌕ Search

Biomedical subjects

Lawrence D Dorr

Publications and source records attributed to Lawrence D Dorr.

At least 37 records · Page 2Linked to original sources
PubMed2004

An American experience with metal-on-metal total hip arthroplasties: a 7-year follow-up study.

This study reviews the clinical performance of 161 hip arthroplasties (154 patients) with the Metasul metal-on-metal articulation and an uncemented modular acetabular component. Between 1995 and 2002 clinical evaluation and radiographic follow-up of patients included Harris hip scores, patient self-assessment, and radiographs. Twelve operative site complications (7.5%) included 6 revision operations, (3.7%) and 3 other complications (1.9%) not needing reoperation. Six revision operations (3.7%) included 1 femoral revision for aseptic loosening (0.06%) and 5 acetabular revisions (3.1%). One cup revision was for recurrent dislocation, 1 for disassociation of the acetabular insert from the cup, 1 for infection, and 2 for unexplained pain. Histologic evidence did not support the diagnosis of metal hypersensitivity in either case of unexplained pain, and 1 had relief following spine surgery. A focal radiolucency, identified as calcar resorption, was observed in 9 patients.

Adult↗
PubMed2004

Assessment of bone graft substitutes in autopsy implant retrievals of the acetabulum in total hip arthroplasty.

Two autopsy retrievals of acetabular reconstruction with different bone graft substitutes were analyzed. One patient underwent surgery with hydroxyapatite (HA) granules, and the other with demineralized bone chips. Incorporation occurred with the biomaterial bone-graft substitute HA primarily in the superior part of the acetabulum, where the HA was in contact with host cortical bone. No bony union occurred with the demineralized bone chips because of motion and migration of the acetabular cup. No bone incorporation of either bone-graft substitute was observed in the medial wall defects in both patients. There were two important findings: (1) the 3- to 8-mm depth and 70% to 75% surface of union of the HA bone graft substitute to host cortical bone was the same as seen with morselized, fresh-frozen bone graft; and (2) union of graft material to host bone was dependent on secure fixation of the acetabular construct.

Acetabulum↗
PubMed2004

The argument for the use of Metasul as an articulation surface in total hip replacement.

Metasul metal-on-metal articulations have been used for 15 years in approximately 300,000 total hip replacements. We have used Metasul articulations in three clinical studies and have shown clinical success as measured by Harris hip scores and patient self-assessment; we also have had the usual mechanical complications. The only complications have been mechanical, including two cup loosenings and 24 dislocations in a total of 582 patients (619 hips; 3.8%) who had Metasul articulations and were included in these studies. In the randomized study, the group who had Metasul articulations had no clinical results or complications different from the control ceramic-on-polyethylene group. Authors of retrieval results in the literature report low annual linear wear rates and no consequences of elevated Co ion levels. Currently, the scientific evidence of the results of using the Metasul articulation would recommend its continued use in any patient who does not have compromised renal function.

Adult↗
PubMed2004

Initial stability of cemented femoral stems as a function of surface finish, collar, and stem size.

BACKGROUND: The optimum surface roughness of cemented femoral stems used for total hip replacement is a subject of controversy. While rougher surfaces provide stronger cement adhesion, it has been hypothesized that polished, tapered, noncollared stems settle into the cement mantle, providing improved stability. However, the effects of surface finish on the stability of straight, cemented stems tapered only in the coronal plane are not known. METHODS: Using composite model femora, we assessed the initial stability of a straight, cemented femoral stem as a function of surface roughness, the presence or absence of a collar, stem size, and the resultant cement thickness under simulated walking and stair-climbing loads. Otherwise identical stems were manufactured with polished or rough surfaces, with or without a collar, in two different sizes. We isolated these three variables and compared their relative contributions to the motion at the stem-cement interface throughout cyclic loading. We defined three indicators of stability: per-cycle motion, rate of migration, and final migration. RESULTS: Surface roughness had a greater influence on per-cycle motions than did the presence or absence of a collar or cement thickness. Specifically, in the medial-lateral direction, per-cycle motion of polished stems was 43 micro m greater than that of rough stems (p < 0.01). None of the per-cycle motions decreased over the 77,000 load cycles. In contrast, with all stems, the rate of migration decreased over the course of cyclic loading, but the rate of migration of the polished stems was greater than that of the rough stems. Final migrations of the stems over the course of loading were generally distal, medial, and into retroversion. Compared with rough stems, polished stems had 8 to 18 micro m more axial migration (p < 0.001), 48 micro m more anterior-posterior migration (p < 0.001), and 0.4 degrees more rotational migration (p = 0.01). CONCLUSIONS: and CLINICAL RELEVANCE: The results indicated that, for cemented, straight femoral stems tapered only in the coronal plane, a rough surface offers the advantage of less per-cycle motion. These results may apply to widely used cemented stem designs based on the profile of the original Charnley femoral component, which has approximately parallel anterior and posterior aspects.

Arthroplasty, Replacement, Hip↗
PubMed2004

Comparison of proximal porous-coated and grit-blasted surfaces of hydroxyapatite-coated stems.

BACKGROUND: It remains controversial whether a proximal porous coating is superior to a grit-blasted surface with regard to providing femoral stem fixation in total hip arthroplasty. We examined the hypothesis that a proximal porous coating would provide better fixation than would a fully grit-blasted surface of otherwise identical proximally hydroxyapatite-coated stems. METHODS: In a prospective study, seventeen patients (thirty-four hips) underwent bilateral sequential total hip replacement with the Anatomic Porous Replacement at the same operation. A proximally porous-coated femoral stem was implanted on one side, and a stem of the same design but with a proximal grit-blasted surface was implanted in the contralateral hip. A proximal hydroxyapatite coating was applied to the metallic substrate of both stems. The patients were followed for a mean 2.5 years and then were assessed radiographically and clinically with the Harris hip score. RESULTS: With the numbers available, no significant clinical or radiographic differences were found between the two cohorts. Thirty of the thirty-four hips had an excellent result, two were rated good, and two were rated fair. All hips had stable osseous fixation of the stem radiographically. The two types of stems were associated with the same pattern of adaptive bone-remodeling. CONCLUSIONS: In the first two years following total hip arthroplasty, hydroxyapatite-coated proximally porous-coated femoral stems do not provide fixation that is superior to that provided by hydroxyapatite-coated grit-blasted stems. LEVEL OF EVIDENCE: Therapeutic study, Level II-1 (prospective cohort study). See Instructions to Authors for a complete description of levels of evidence.

Adult↗
PubMed2004

Effects of dorsal flanges on fixation of a cemented total hip replacement femoral stem.

BACKGROUND: Although current designs of cemented femoral stems for total hip replacement include both those with and those without a flanged shape at the proximal end, the influence of anteroposterior dorsal flanges on the fixation of the stem is not completely understood. The purpose of this study was to assess the effects of flanges on femoral stem stability and load transfer to the femur with use of an in vitro model. METHODS: We measured femoral surface strains and three-dimensional micromotion in synthetic femora under cyclic loading with four types of stems: those with flanges and those without flanges in two sizes each. The four types of stems were otherwise identical; that is, all of them were straight, polished, and collarless. Stem-cement micromotion measurements and strain measurements were repeated with three stems of each type, whereas bone-cement micromotion measurements were made with one stem of each type. RESULTS: Flanges had a greater influence on femoral strains and micromotion than did the difference in the cement thickness resulting from the different stem sizes. Specifically, the flanged stems produced greater strains on the medial femoral surface but smaller strains on the anterior surface than did the non-flanged stems. Flanged stems achieved tighter mechanical interlock within the cement, but these stems increased bone-cement micromotion. Specifically, the motion per cycle of flanged stems within the cement mantle was smaller than that of non-flanged stems, whereas the motion per cycle of the cement mantle within the femoral canal was greater with the flanged stems than with the non-flanged stems. CONCLUSIONS: Flanges on a total hip femoral stem increase the interlock between the stem and the cement and decrease the proximal-medial stress-shielding. However, these advantages occur with increased bone-cement interface motion, which may be detrimental to the survival of the implant.

Adult↗
PubMed2003

Measurement of polyethylene wear in total hip arthroplasty--accuracy versus ease of use.

The aim of this study was to compare the accuracy of four different methods for measuring wear using an apparatus that simulates known amounts of three dimensional wear. Wear was measured using the manual methods reported by Charnley, Livermore, Dorr and Wan and the computerized method reported by Devane. Only the method reported by Devane measured the three-dimensional (superior and anterior) wear with a reasonable accuracy, with a mean measurement error of 0.21 mm. With superior wear alone, Charnley's method underestimated the extent of wear by 16.6%, with a mean error of 0.35 mm; Livermore's method estimated wear to within 9.5%, with a mean error of 0.16 mm; Devane's method estimated wear to within 9.5%, with a mean error of 0.15 mm; and Dorr's method underestimated wear by 25.4%, with a mean error of 0.56 mm. Dorr's method was modified as a result of the experimental tests. The clinical application of the new method showed comparable data to that using the Devane method. In conclusion, this new method can be used to estimate the average wear in groups of patients accurately.

Equipment Failure Analysis↗
PubMed2003

Self-inflicted risks of orthopaedic surgery.

The advancements in medicine, including orthopaedic treatment, since 1960 have so greatly improved quality of life that human nature has changed in its social goals. These technological innovations, especially the products created, have resulted in a self-inflicted increase in risk of practice. This risk will not be leveled until society recognizes that it expects that the physician not only be a healer, but able to fulfill the social goals of the patient.

History, 20th Century↗
PubMed2003

The risk of product liability: orthopaedic surgeons can be trapped.

Orthopaedics has become the specialty that it is because of the technologic advancements of medicine in designing successful implants. However, the use of implants introduces a new risk of product failure. The orthopaedic surgeon needs to be aware of the potential consequences of the risks of use of devices in treating patients.

Humans↗
PubMed2003

A biomechanical analysis of polyethylene liner cementation into a fixed metal acetabular shell.

BACKGROUND: A common clinical scenario encountered by an orthopaedic surgeon is a patient with a secure cementless acetabular shell and a failed polyethylene liner. One treatment option is to cement a new liner into the fixed shell. The purpose of this study was to evaluate technical variables to improve the mechanical strength of such cemented liner constructs. METHODS: The contributions of shell texturing, liner texturing, and cement mantle thickness (between the liner and the shell) were evaluated by comparing torsional strength (among nine groups of constructs) and lever-out strength (among eight groups of constructs). RESULTS: Failure almost always occurred at the cement-liner interface. The two exceptions (failure at the shell-cement interface) occurred with a polished, untextured shell with no screw-holes. This finding indicates that if a shell has existing texturing (such as holes), further intraoperative scoring of the shell is unnecessary, but some sort of texturing is necessary to avoid construct failure at the shell-cement interface. Textured liners had significantly (a = 0.05) greater torsional and lever-out strength than untextured liners. The greatest construct strength occurred when liner grooves were oriented so as to oppose the applied loading. A 4-mm-thick cement mantle resulted in slightly greater torsional strength than a 2-mm-thick cement mantle, and a 2-mm-thick cement mantle resulted in considerably greater lever-out strength than a 4-mm-thick cement mantle, but these differences were not significant. CONCLUSIONS: When cementing a liner into a well-fixed shell, a surgeon should ensure that both the shell and the liner are textured, as interdigitation of the cement with the shell and the liner is crucial to the mechanical strength of this construct.

Arthroplasty, Replacement, Hip↗
PubMed2003

Accuracy of measurement of polyethylene wear with use of radiographs of total hip replacements.

BACKGROUND: Although a number of methods are used to estimate polyethylene liner wear from radiographs of total hip replacements, there is no consensus with regard to the accuracy of these methods. The purpose of this study was to compare the accuracy of several such measurement methods with use of both laboratory radiographs and routine clinical radiographs. METHODS: A phantom apparatus was designed to simulate random values of three-dimensional wear, with varying degrees of cup abduction and anteversion, and to obtain anteroposterior and cross-table lateral radiographs with each value. Wear was measured with use of the Charnley duoradiographic method, the Livermore method, and the method described by Dorr and Wan, as well as with use of PolyWare and Hip32 software packages, both with and without three-dimensional measurements. Clinical wear was measured from conventional radiographs made prior to revision surgery in fourteen patients and was compared with wear measured directly from the retrieved liners with use of a coordinate measuring machine. RESULTS: With laboratory radiographs, median errors were 0.1 mm with the Livermore method and both computerized methods, 0.23 mm with the Charnley method, and 1.7 mm with the method of Dorr and Wan. Maximum errors were between 0.6 mm (Livermore) and 4.3 mm (Dorr and Wan). In contrast, with use of clinical radiographs, median errors ranged between 0.2 mm (Hip32) and 0.6 mm (Dorr and Wan). Maximum errors ranged between 1.8 mm (Dorr and Wan) and 2.5 mm (Livermore). CONCLUSIONS: With laboratory radiographs, computerized methods of polyethylene wear measurement offered distinctly greater accuracy than did manual methods; however, with clinical radiographs, they offered only slightly better accuracy. Although the increased accuracy of computerized methods may be necessary in research settings, manual methods provided sufficient accuracy for routine clinical assessment of wear.

Arthroplasty, Replacement, Hip↗
PubMed2002

Fixation of the millennium: the knee.

Current reports of noncemented fixation for total knee arthroplasty show that fixation of the components is durable for 20 years. Noncemented fixation may be preferable in patients <60 years old. In revision total knee arthroplasty, cemented stems are preferable in patients >70 years old.

Age Factors↗
PubMed2002

Polyethylene liner cementation into fixed acetabular shells.

A patient presenting with a secure cementless acetabular component and with femoral head penetration through the polyethylene liner is a common clinical problem. Cementing a new liner into the fixed shell is one option. We evaluated this option in a clinical series of 17 cases and with a preliminary mechanical study. In the 1 clinical failure (5.9%), the failure occurred at the cement-liner interface. The most important variable in optimizing the mechanical strength of the cemented liner construct was adequate preparation of the cement-liner interface. This approach to treating the patient with a fixed cementless shell and a worn polyethylene liner can provide a durable construct with minimal morbidity.

Aged↗