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Biomedical subjects

L Walter

Publications and source records attributed to L Walter.

66 records · Page 4Linked to original sources

[Results of rapid intraoperative biopsies in breast neoplasms].

200 intraoperative biopsies of mamma tumors are demonstrated. Carcinomas of mamma are divided due to frequency of histological type. Intraoperative diagnostic procedures are valuable to confirme malignant tumors, especially that patients are to be spared of second operation day.

Biopsy↗

Allergic interstitial nephritis: report of a case with activation of complement by the alternate pathway.

An eighteen year old woman developed a streptococcal pharyngitis documented by throat culture. After two days of treatment with penicillin she developed arthritis and abdominal pain and within a week became anuric. Her renal biopsy revealed extensive interstitial nephritis without proliferative glomerular changes. Serum properdin levels were significantly reduced and immunofluorescence studies demonstrated properdin deposition within the glomeruli, C1, C4 and C2 were not depressed nor were they demonstrable within the glomeruli. These results support activation of complement apparently only by the alternate pathway, a finding heretofore noted only in membranoproliferative glomerulonephritis.

Adolescent↗

Blood and plasma concentrations of butalbital following single oral doses in man.

Blood and plasma concentrations of butalbital (from Fiorinal) were determined in a small group of healthy volunteers after single oral doses of 100 mg of butalbital. Butalbital was quantitated by high-performance liquid chromatography with ultraviolet detection. Typical blood concentrations of butalbital peaked at 2.1 mg/L and declined to 1.5 mg/L at 24 h. The half-lives in blood were between 35 and 87.5 h with a mean of 61 h. Whole blood to plasma ratios were also determined.

Administration, Oral↗