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Biomedical subjects

L Puig

Publications and source records attributed to L Puig.

At least 109 records · Page 6Linked to original sources
PubMed1989

Factitial dermatosis of the breast: a possible dermatologic manifestation of Munchausen's syndrome.

We report on two cases of factitial dermatosis of the breast associated with benign fibrocystic disease. One of the patients could also be diagnosed as showing Munchausen's syndrome. The lesions were protracted and intractable, painful ulcers that recurred and eventually became bilateral, despite attempts at surgical correction. The management of factitial dermatosis of the breast is complex, and should include psychiatric referral as well as avoidance of further surgical treatment if possible.

Adult↗
PubMed1988

Acquired pachydermatoglyphy. A cutaneous sign of internal malignancy.

A 70-year-old man with hypertrophic osteoartropathy secondary to a squamous cell carcinoma of the lung presented a distinctive pattern of late-onset bilateral palmar keratoderma. A yellowish rugose appearance with accentuation of normal ridges and sulci (pachydermatoglyphy) involving the palms was observed. The differential diagnosis and the clinical relevance of acquired pachydermatoglyphy as a cutaneous marker of internal malignancy are discussed.

Acanthosis Nigricans↗
PubMed1988

Erythema gyratum atrophicans transiens neonatale: a variant of cutaneous neonatal lupus erythematosus.

We cared for a patient with neonatal lupus erythematosus with cutaneous and hepatic involvement that was clinically and histologically indistinguishable from erythema gyratum atrophicans transiens neonatale, an entity described by Gianotti and Ermacora in 1975, which we consider to be a subtype of cutaneous neonatal lupus erythematosus. The differential diagnosis of any annular erythema in the newborn requires careful clinicopathologic evaluation, with direct immunofluorescence studies and determination of anti-Ro/SS-A, anti-La/SS-B, and anti-nRNP antibodies in both the baby and the mother.

Age Factors↗
PubMed1988

[Pigmented dermatofibrosarcoma protuberans (Bednar's tumor)].

Pigmented dermatofibrosarcoma protuberans, first described by Bednar under the term storiform neurofibroma, is an infrequent neoplasm accounting for 1 to 5% of cases of dermatofibrosarcoma protuberans. Bednar's tumor is composed of spindle shaped cells arranged in a distinctive storiform or carthwheel pattern, and melanin-containing dendritic cells scattered within the tumor. The differential diagnosis with (non-pigmented) dermatofibrosarcoma protuberans is based on the presence of this population of pigmented cells. Two cases of pigmented dermatofibrosarcoma protuberans (Bednar's tumor) are reported here in, and a discussion follows on the clinicopathological features of this neoplasm and the different hypotheses on its histogenesis.

Adult↗
PubMed1988

[Chronic mucocutaneous candidiasis].

Chronic mucocutaneous candidiasis is a chronic infection of mucoses, nails and skin due to Candida sp., that does not respond to standard treatment. We report on three patients with chronic mucocutaneous candidiasis in association with iron deficiency, IgA deficiency in one patient and adult onset in another. We review the clinical manifestations, the classification and the treatment of this disorder. The immunologic defects associated with chronic mucocutaneous candidiasis provide a model to study the mechanisms of defense of the host against fungal infections.

Adult↗
PubMed1988

Von Recklinghausen neurofibromatosis with carcinoid tumor and submucous leiomyomas of the duodenum.

We report on a 63-year-old man with von Recklinghausen neurofibromatosis who developed a carcinoid tumor in the periampullary region and multiple small-sized leiomyomas in the duodenal wall. A high prevalence of gastrointestinal carcinoids has previously been recognized in patients with von Recklinghausen neurofibromatosis, the commonest site of origin being the duodenum or the periampullary region. The association of both conditions seems to be more than casual. Abnormalities in the development of the complex of von Campenhout or high circulating levels of nerve growth factor have been the mechanisms postulated to account for this association.

Carcinoma↗
PubMed1987

Verrucous hemangioma.

Verrucous hemangioma is an infrequent variety of deep-seated capillary or cavernous hemangioma with reactive epidermal hyperplasia and a superficial component indistinguishable from those of angiokeratoma. Four cases of verrucous hemangioma are reported herein. Verrucous hemangiomas are usually congenital lesions which do not resolve spontaneously and have a tendency to recur after excision if margins are inadequate. Careful histopathologic and clinical evaluation are required for an optimal therapeutic approach.

Adult↗
PubMed1987

[KID syndrome (keratitis-ichthyosis-deafness)].

The KID syndrome is characterized by congenital ichthyosis, vascular keratitis and neurosensorial deafness. We report a 17 year old female patient, the first case of KID syndrome in Spanish literature. Red, dry, scaling skin was present at birth with sparse hair. At the age of six, malar erythema was prominent, with perioral ragades and onset of progressive neurosensory deafness. At the age of ten, vascularizing keratitis developed. At 12, treatment with etretinate failed to improve the ichthyosis. We review the clinical, pathological and analytical features of KID syndrome and discuss its relationship to other ichthyoses.

Adolescent↗
PubMed1987

[Monoclonal antibodies in pigmented lesions].

We have applied a battery of murine monoclonal antibodies (R-24, L-101, S-171) to the immunohistological diagnosis of 35 pigmented lesions. The results of our study allow us to conclude that: 1) The monoclonal antibody R-24 is a good marker of normal and neoplastic melanocytes, although some melanomas do not stain with this monoclonal antibody. The application of R-24 may contribute to the pathologic differential diagnosis of melanoma metastases. 2) The association of R-24+ and L-101+ staining is found in melanocytic nevus as well as in melanomas, and do not allow the differential diagnosis between them. 3) Stains with R-24, L-101 and S-171 are simultaneously positive only in melanomas, and with low frequency.

Antibodies, Monoclonal↗
PubMed1987

Prurigo gravidarum.

Prurigo gravidarum is an infrequent dermatologic condition in pregnant patients that has been found to be associated with an increased incidence of perinatal and obstetric complications. We present ten cases of this finding and review the pathogenesis, therapy, and complications of prurigo gravidarum. The recognition of this entity by dermatologists, obstetricians, and general practitioners should prompt referral of these patients for high-risk obstetric care.

Adult↗