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Biomedical subjects

L King

Publications and source records attributed to L King.

At least 163 records · Page 9Linked to original sources

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Comprehensive Health Care↗

The ion channel switch biosensor.

A biosensor technology is described which provides a direct measurement for functional molecular interactions, at the surface of a tethered bilayer membrane, through the electrical transduction of chemically modified ion-channels. High sensitivity of analyte detection is achieved due to the large flux of ions transmitted through the ion channel. The biomimetic sensor surface allows the molecular recognition to be measured in complex biological matrices (such as blood and sera) without compromising sensitivity. We have used the sensor for activity and concentration measurements for a range of analytes, which include bacteria, DNA, proteins and drugs. We have a quantitative model for the biosensor performance which is described by three-dimensional molecular interactions with the membrane surface and two-dimensional molecular interactions within the tethered bilayer.

Biosensing Techniques↗

Safe handling of hip replacement patients.

This article aims to promote understanding of the potential causes of dislocation in post-operative hip replacements as well as the dangers of back injury to nurses handling these patients. A questionnaire survey of orthopaedic surgeons revealed where practice could be changed from the traditional 'lift only' procedure in compliance with the new EC safety regulations for manual handling.

Biomechanical Phenomena↗

Impaired wound healing in patients with diabetes.

BACKGROUND: This article reviews a cross-section of literature on wound healing and highlights how diabetes mellitus can cause deviations from usual healing patterns. CONCLUSION: Nursing interventions can either enhance or delay the healing process. Nurses need to understand the defective processes to optimise the available healing potential.

Diabetes Complications↗