Organization, administration and the environment.
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Biomedical subjects
Publications and source records attributed to L J Moore.
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Tooth transplants should not preclude future transplants in the recipient. In this study teeth failed to stimulate immunologic memory in weakly disparate mice. The teeth did carry transplantation antigens and were rejected after second-set skin grafts. The teeth probably enhanced their own survival through some immunoregulatory mechanism.
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The residual effect of premature loss due to extraction of the four maxillary primary incisors on speech production was studied. The articulation of twenty-six subjects who had their teeth extracted before the age of five years was evaluated at eight, nine, or ten years old and compared with the articulation of an age-matched comparison group with normal exfoliation of their incisors. T-tests for related measures revealed no statistically significant differences between the group with premature loss and the comparison group. These results suggest that loss of maxillary incisors in children younger than five years is not likely to result in defective articulation while the teeth are missing or when the permanent dentition is acquired.