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Biomedical subjects

L Hohenauer

Publications and source records attributed to L Hohenauer.

At least 73 records · Page 4Linked to original sources

[Assessment of gestational age (author's transl)].

Both the birth weight and the relation of birth weight to gestational age are relevant factors in assessing the immediate and future risks in given newborn infant. When gestational age is known the assessment is done by using an intrauterine growth chart. In cases of unknown gestational ages, in cases of discrepancies between birth weight and gestational age the gestational age of the infant has to be clinically assessed. This assessment can be done by evaluating the neurologic or the external criterias both giving an accuracy of +/- 2 to 3 weeks.

Birth Weight↗

[Transcutaneous measurements of pO2 in newborns with RDS (author's transl)].

pO2 was measured transcutaneously (commercially available Clark Electrode, Bioelectronics Roche) with two different electrode temperatures in new born infants. The correlation between paO2 (arteria radialis) and ptcO2 was bad (r= 0,74) with electrode temperature of 42 degrees C. When the electrode was heated to 44 degrees C there was a very good correlation (r= 0,969) in 80 simultaneous measurements of paO2 (umbilical arterial catheter) and ptcO2. The mean values and standard deviations of pO2 values in hypoxic, normoxic and hyperoxic states are very similar: hypoxic: paO2 34,3 "/- 7,9, ptcO2 35,2 +/- 14,0, normoxic: paO2 78,7 +/- 14,3 ptcO2 78,8 +/- 16,7, hyperoxic: paO2 141,8 +/- 37,1, ptcO2 134,4 +/- 40,8 mmHg). The specific advantage of transcutaneous measurements is the trend registration for hours. With electrodes temperatures of 44 degrees C however, there is a risk of superficial burns if the electrode is attached to the identical site for 6 hours or more.

Electrodes↗

[Development after respiratortreatment during the newborn period (author's transl)].

There were 17 survivors of severe neonatal respiratory distress treated with IPPV for more than 24 hours (36-520 hrs, mean duration of IPPV 6 days) followed into the second year of life. 11 of these young children were physically and neurologically normal. 3 were developmentally retarded (3 months or more), 2 had neurological defects without mental subnormality. These defects (Hemiplegia and Diplegia) were correlated with low gestational ages (32 and 33 weeks respectively) 1 child was severely defective. This one was treated because of apnea caused by seizures in postmaturity syndrome (44 weeks gestation). The overall incidence of defects was 3/17 (= 17%).

Cerebral Palsy↗

[Fototherapy of neonatal hyperbilirubinemia. Results of its clinical application (author's transl)].

The application of fototherapy according to the indications listed by Maisels (1972, Abb. 1) has brought about a 67% reduction in exchange transfusions in comparison to the controll period proceeding this new regimen. This reduction of the need of exchange transfusions was especially striking in cases of hyperbilirubinemia of full term babies without blood group incompatibilities and in A B O incompatibilities with mild hemolysis. In typical Rh-incompatibility the number of repeat exchange transfusions diminished by 75%. The serum bilirubin levels of 206 consecutive low birth weight infants were prospectively investigated. 77 infants (37%) reached a serum bilirubin level of 10 mg% and were treated with fototherapy. Only 9,6% of these lowbirth weight infants had maximum serumbilirubin levels of 12 mg% or more and only 1,5% had levels of 15 mg% or more. Fototherapy reduces the risk of Kernikterus in Low birth weight babies to a minimum and it can reduce the risks and the costs of treatment for many icteric full term babies by reducing the number exchange transfusions needed. Inspite of its simplicity and effectiveness it has to be stressed that fototherapy should only be used under well defined indications and in a technically correct way.

ABO Blood-Group System↗

[One year's experience with mechanical ventilation in newborn infants (author's transl)].

During the first year of newborn intensive care at the Landeskinderkrankenhaus Linz/Donau there were 80 cases of artificial ventilation, 62 of these were Low Birth Weight Infants (LBWI). 12% of all LBWI required mechanical ventilation. 53 ventilated infants suffered from severe Hyalin Membrane Syndrome (HMS). 17 survived, 18 died of intraventricular hemorrhage and 18 died of HMS. Bronchopulmonary Dysplasia was found in all patients ventilated for more than 7 days. 5 cases of pneumothorax occurred during ventilation. Good results were obtained in cases of respiratory insufficiency other than HMS (15 cases, 12 survivors. Mortality rate of LBWI delivered in Hospitals was 9.9%, whereas 34% of the LBWI delivered at home but cared for under identical conditions in the nursery died. This difference offers good evidence for the importance of the quality of the obstetrical care for the results of newborn intensive care.

Austria↗

[Neuromotor follow-up of premature infants with lowbirth-weight (author's transl)].

In the years 1971-1972 53 premature babies weighing between 1000-1500 g survived in the special department of the Linz hospital ward for premature children i.e. 45.5%. Their postnatal management and neurophysiologic follow-up are reported. 20 children were "normal", 38% had slight, 20% more pronounced developmental delay. In 81.4% there were in addition minimal disturbances of movement. 2 had severe spastic tetraplegia. The study of these data indicated ways of improvement which have been effected since.

Birth Weight↗