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Biomedical subjects

L Forsberg

Publications and source records attributed to L Forsberg.

At least 55 records · Page 3Linked to original sources

One hundred impotent men.

One hundred men complaining of poor or absent erectile capacity were investigated with a multidisciplinary approach. Their median age was 47 years. Mainly organic causes of the erectile failure were found in 27 and mainly psychologic in 40 cases, while factors of both types contributed in 33 cases. Vascular disorder was present in 20 men, including (functional) vasoconstriction in eight. Among 24 men with serum testosterone below 15 nmol/l the incidence of arterial disease, alcoholism and partner-related problems was significantly higher than in those with higher testosterone levels. Most psychologic factors were in general intrapsychic (affecting only the patient himself), while a minority were dyadic (related to the partner).

Erectile Dysfunction↗

Entrapped ovarian cyst. An unusual case of persistent abdominal pain.

Recurrent abdominal pain in the left fossa often mimicking attacks of subileus is described in a woman aged 48 with extensive adhesions caused by multiple surgical procedures. Repeated examinations with conventional abdominal radiography and barium meals were negative with regard to mechanical intestinal obstruction. A cystic lesion varying in size from 2 to 8 cm in diameter was seen adjacent to the left ovary on repeat US examinations and also on CT. Pain episodes were sometimes correlated to increasing size of the lesion which was finally thought to be either a peritoneal inclusion cyst (fluid trapped between pelvic adhesions) or, as was finally confirmed at surgery, a true ovarian cyst (corpus luteum cyst) similarly trapped.

Abdominal Pain↗

Ultrasonography and Doppler Duplex compared with angiography in follow-up of mesocaval shunt patency.

Thirty-four patients with portal hypertension of various etiologies were operated upon with an interposition mesocaval Goretex graft. During a period of 6 years 84 angiographic and ultrasonographic (US) examinations (53 B-mode, and 31 Doppler Duplex) were performed, with few exceptions within 3 days. Angiography served as the 'gold standard'. Shunt patency was correctly interpreted as normal in B-mode US in 38 examinations. Shunt occlusion, definite or probable, was seen in 12 B-mode examinations, where angiography demonstrated occlusion in 6 and patency in the remaining 6 shunts. Shunt occlusion was not observed sonographically in one examination. US was technically inadequate on two occasions. Doppler Duplex showed shunt patency in all 31 examinations, which was correct according to angiography. Both B-mode US, in 6 out of 6 examinations, and Doppler Duplex, in 7 out of 9 examinations failed to reveal shunt stenosis. Five patients with abundant venous collaterals (in one case with aberrant vascular anatomy) were not possible to evaluate even after the introduction of Doppler Duplex, which otherwise facilitated the evaluation. We suggest that US including Doppler should be the primary modality for follow-up in patients with interposition mesocaval Goretex grafts.

Adolescent↗

Diagnosis and percutaneous treatment of pyogenic hepatic abscesses.

Twelve patients with intrahepatic abscesses were examined with computed tomography and ultrasonography between 1979 and 1988. The median size of the lesions was 7 (1-12) cm. They were in 8 patients located only in the right liver lobe and in 3 in both liver lobes. On ultrasonography the echogenicity of the abscesses varied from hypo- to hyperechoic which is consistent with tumours. The final diagnosis of abscess was achieved by fine needle puncture and aspiration for bacterial culture. Nine patients were treated with percutaneous drainage. 3 of them with two catheters, and all received systemic antibiotic treatment. All patients survived the treatment.

Aged↗

Percutaneous puncture and drainage of pancreatic pseudocysts. A retrospective study.

Experience with 19 consecutive patients who had 20 pancreatic pseudocysts treated by percutaneous puncture and/or drainage was reviewed. Ten pseudocysts (5 infected, 5 non-infected), underwent complete resolution after percutaneous treatment only and there was a considerable regression in 6 (5 infected, 1 non-infected), which means an overall cure rate of 80 per cent. Only one small pseudocyst remained unchanged. Complementary surgery was necessary in 3 cases. Fine needle evacuation was the method in 13 cases (11 cured) and catheter drainage in 7 (5 cured). We conclude that percutaneous drainage is a safe method for the treatment of pancreatic pseudocysts, that will cure the patient in most cases.

Adult↗

[Acute cholecystitis. Percutaneous cholecystectomy guided by ultrasound as a therapeutic alternative for seriously ill patients].

Ultrasound guided percutaneous cholecystostomy was performed in nine episodes of acute cholecystitis in seven patients unsuitable for laparotomy owing to advancedage (mean 79 years) and the presence of other serious disease. No serious complications were observed (the importance of satisfactory local anaesthesia and minimal catheter manipulation is emphasized); and satisfactory pain relief was obtained almost instantaneously. The procedure would seem to be an acceptable alternative to cholecystectomy in cases of severe acute cholecystitis where laparotomy must be avoided.

Acute Disease↗

Liver biopsy complications monitored by ultrasound.

Ultrasound (US) was performed in 96 patients (on 108 occasions) 2-4 h after diagnostic liver puncture with a modified Menghini needle. Serious complications (major haemorrhages: one intraparenchymal and one into the abdominal cavity) were seen in two patients, while seven presented with minor bleedings though without any registered clinical abnormality (slight pain in one). On 11 occasions (10 patients) slight to moderate pain was observed though in combination with a normal US. Findings on US and clinical observations showed poor correlation and the number of bleeding complications discovered by US examination seems to depend upon when the study is performed. US does not replace the clinical follow-up but may be helpful in the presence of adverse clinical reactions in order to establish the type of lesion: profuse parenchymal haemorrhage versus bleeding into the abdominal cavity. This information may be helpful in the choice between conservative and surgical therapy.

Adult↗

Severe arterial insufficiency in impotence confirmed with an improved angiographic technique: the impact of smoking and some other etiologic factors.

Arteriography of the penile arteries in patients with pharmacologic erection has been performed by our group since 1983. Pathological Doppler findings and weak response to locally administered papaverine or alpha-blocking agents in these impotent men led to pharmacoangiography in 17 of 372 patients with erectile dysfunction; of these 372 patients 130 (35%) had subnormal penile blood flow according to Doppler ultrasonography. Only one had a proximal lesion (occlusion of the right common iliac artery) while the rest had distal lesions. Three patients were nonsmokers and the remaining 14 patients (82%) were smokers or had smoked previously. Only 2 of the 14 had other predisposing diseases.

Aged↗

Etiologic aspects of impotence in diabetes.

An investigation of 37 diabetics with impotence (15) or erectile difficulties (22) is presented. On average two significant abnormalities per patient were found. Ranked in order of incidence, the causes were as follows: 1) Combination of neuropathy and psychosocial factors, 2) combination of neuropathy and vascular disease, 3) peripheral neuropathy only, 4) combination of hormonal imbalance and psychosocial factors, 5) combination of three or more defects, and 6) penile vascular disease or psychosocial problems only, or hormonal imbalance combined with peripheral neuropathy.

Diabetic Angiopathies↗

Pharmacoangiography of the penile arteries.

Angiography may play an important role in the evaluation of patients with erectile failure and in whom abnormal Doppler studies indicate arterial insuffiency. The angiographic examination should give information about major pelvic arteries as well as the peripheral branches of the internal pudendal artery. We describe a method for performing pharmacoangiography of the penile arteries, which involves the local injection of a vasodilator into the corpus cavernosum. Angiography during pharmacologic erection provides optimal visualization of the penile arteries and helps to differentiate functional from organic vascular disorders.

Angiography↗

Pharmacoangiographic assessment of penile arteries in patients with erectile failure.

Pudendal angiography was done before and thirty minutes after intracavernous administration of 6 mg phenoxybenzamine in 8 men in whom screening with ultrasound Doppler had revealed abnormalities of the penile blood flow. Five vessels were not visualized until phenoxybenzamine was given. Four vessels displayed marked dilatation, three had moderate and one had slight dilatation after the pharmacologic erection was provoked. The method appears to be of value to increase the quality of the angiographic examination.

Angiography↗

Hepatic ultrasonography in the terminally ill patient.

In 53 patients comparison was made between findings at autopsy and findings at ultrasound (US) examination performed shortly before death as the only morphologic diagnostic procedure of the liver during the patient's last year. US was found to be highly accurate. The non-invasiveness and the possibility of examining the patient in bed make US examination in experienced hands the ideal initial diagnostic procedure, especially in terminally ill patients.

Adult↗

Visceral improvement following combined plasmapheresis and immunosuppressive drug therapy in progressive systemic sclerosis.

In a two-year prospective therapeutic trial, 15 patients with progressive systemic sclerosis (PSS) were treated with immunosuppressive drug therapy with or without long-term plasmapheresis. Before the trial all patients had severe involvement of either the esophagus, lungs or kidneys. One patient died of renal failure and another 2 patients withdrew unimproved. In the remaining 12 patients, objective improvement occurred in all but one. The degree and extent of skin involvement decreased significantly (p less than 0.01). Cineradiography revealed increased esophageal motility in 4 patients. Pulmonary function measured as total lung capacity and static lung compliance improved (p less than 0.01). In 4 patients the number of premature atrial or ventricular contractions at 24 h ECG monitoring decreased, as did the concentrations of immunoglobulins and ANA titres in serum. Although it could not be ascertained whether the clinical improvement was associated with combined therapy or immunosuppressive drug treatment alone, our results suggest that immunosuppressive therapy is beneficial in advanced PSS.

Adult↗

Sonography and joint pressure in synovitis of the adult hip.

Sonography was successfully used to diagnose an effusion in the hips of three adults with septic arthritis and four with aseptic synovitis. The effusions were confirmed by aspiration. All the patients had markedly increased intracapsular pressure which, in the extended position, exceeded the systolic blood pressure and could well compromise the blood supply to the head of femur. Aspiration reduced pain and intracapsular pressure, as did flexion of the hip to 45 degrees.

Adolescent↗