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Biomedical subjects

L Ekelund

Publications and source records attributed to L Ekelund.

At least 55 records · Page 3Linked to original sources
PubMed1984

Segmental hepatic arterial occlusion with absolute ethanol in domestic swine.

Four to five ml of absolute ethanol was injected into a segmental hepatic artery in eight pigs to study the occlusive effect on the hepatic arterial system. Liver cell damage was indicated by a transient moderate elevation of liver enzymes. Follow-up angiography at various time intervals showed persistent occlusion of intrahepatic arteries at different levels in all pigs and occlusion of the common hepatic artery in four. Reconstitution of the intrahepatic arterial circulation via abundant intrahepatic collaterals was, however, observed. Microscopic examinations demonstrated arterial thrombi and necroses in the vascular walls as well as a great variation in the extent of liver parenchymal damage.

Alanine Transaminase↗
PubMed1984

Increased kidney size following renal angioplasty. A 'new' observation.

Percutaneous transluminal renal angioplasty was performed in nine patients (10 kidneys). Immediately following dilatation of the renal artery stenosis, seven of ten kidneys increased in length by at least 0.5 cm (0.5-1.5 cm) indicating improved renal perfusion. This is an observation that does not seem to have been described before. Another, but rare, cause of renal enlargement following angioplasty is hematoma formation which was seen in one of the cases. All of the patients responded well to the treatment and five previously hypertensive patients became normotensive shortly after dilatation.

Adult↗
PubMed1984

Ileopectineal bursitis following total hip replacement.

Two cases of ileopectineal bursitis following total hip replacement are presented. Inflammation, infection and trauma are discussed as pathogenic factors. The results of fine needle biopsy, radiologic examination including CT and ultrasonography, as well as bacteriological cultures are described. The therapy was surgical in both cases.

Adult↗
PubMed1984

Favourable results of acrylic cementation for giant cell tumors.

A consecutive series from two university hospitals of 50 patients with giant cell tumors was reviewed and histologically reconfirmed. The patients treated with curettage and acrylic cement were re-examined concerning function. Two of 14 cemented tumors had recurred but could be treated by additional cementation, so that no final failure of this method had occurred, compared to one of 19 radically resected and 12 of 22 with bone-graft after curettage. Joint function was normal in 11 and radiographic arthrosis of low grade was found in only two of 14 patients. It is concluded that this method gives a minimum of recurrence and a maximum of function. It is suggested that the old name of "giant cell sarcoma" should be reintroduced, bringing the tumor into the group of low-grade sarcomas where it belongs.

Adolescent↗
PubMed1984

Total hip replacement with spongious bone graft for acetabular protrusion in patients with rheumatoid arthritis.

Total hip replacement (THR) with the use of autogenous spongious bone graft reinforcement to the medial acetabular wall proved a successful surgical procedure in patients with rheumatoid arthritis and acetabular protrusion. In 25/26 THR followed for an average of 2 (1-4) years, the bone grafts healed in place radiographically and no further protrusion occurred. A non-progressive radiolucent zone of 3 mm at the bone-cement interface occurred around one acetabular cup. Recurrent dislocations occurred in one hip, which eventually turned out to have a loose acetabular cup. One hip with a firmly seated cup was converted to a resection arthroplasty 4 months after the primary operation because of deep infection.

Acetabulum↗
PubMed1984

Roentgen stereophotogrammetric analysis of neurocranial suturectomy in rabbits.

This investigation was conducted to further elucidate both the significance of a calvarial suture and the compensatory ability of the cranial vault. Four-week-old male New Zealand White rabbits were subjected to unilateral or bilateral extirpation of the coronal suture after insertion of metallic markers, and were then followed regularly by roentgen stereophotogrammetry until age 21 weeks. Bilateral extirpation of the normal coronal suture resulted in a dramatically increased initial rate of bone separation, which tended to remain supranormal for the rest of the investigation. Unilateral suturectomy showed differences in growth between the sides, the operated side initially separating significantly more than the other. Volumetric calvarial growth in rabbits with unilateral extirpation terminated similar to that in control animals, while volumes in rabbits with bilateral extirpations constantly exceeded control volumes, finally exceeding these by 65%. Responses at intact sutures confirmed the compensatory capacity of cranial vaults. The results indicate that the passive longitudinal and volumetric cranial vault bone growth responds quickly to growth disturbances, thereby demonstrating its plasticity, and that the neurocranial suture is a restraining and modulating component in cranial growth.

Animals↗
PubMed1984

New diagnostic modalities in the diagnosis of primary and recurrent giant-cell tumors of bone.

Computed tomography (CT) and/or digital subtraction angiography (DSA) were performed on four patients with primary or recurrent giant-cell tumor of bone. In three cases presented, the tumor was examined with CT and had a precontrast attenuation value of about +50 to +65 HU with unequivocal nonhomogeneous contrast enhancement. In both cases in which DSA was used, contrast-medium enhancement could be recorded by DSA that had definitely not been seen with conventional angiography. It is suggested that in the future CT and DSA may replace conventional angiography in the diagnostic workup of giant-cell tumors.

Adolescent↗
PubMed1983

Pulmonary surfactant release in fetal rabbits: immediate and delayed response to terbutaline.

The fetal lung responds to beta-receptor agonists with a release of surfactant from type II alveolar cells, if such stimulation were intense or long-lasting, the supply might become depleted and, while the supply is being restored, there could be a surfactant deficiency. With experiments on pregnant rabbits, this hypothesis was put to the test and found to be true. At a gestational age of 27.75 days, fetuses received the beta 2-receptor agonist terbutaline, 0.1 or 0.01 mg intramuscularly, or saline only. At the same stage of pregnancy, other does were infused with 7.2 to 9.6 mg of terbutaline or given Ringer's solution. The fetuses were put to death at intervals of 1 to 48 hours, and the lungs were examined. At 1 hour and also at 2 and 3 hours after injection of 0.1 mg of terbutaline, pressure-volume loops demonstrated improved compliance and stability compared to those of controls, but at 24 hours the situation was reversed. At 48 hours there was no difference. At 12 hours from the start of the infusion, pressure-volume loops clearly showed that fetuses of does receiving terbutaline were at a disadvantage. We conclude that terbutaline depleted surfactant stores and, while these stores are being replenished, there is a surfactant deficiency in the alveolar space. Phospholipid analysis supported our conclusion.

Animals↗
PubMed1983

The value of angiography in soft tissue leiomyosarcomas of the extremities.

The angiographic findings in eight patients with soft tissue leiomyosarcoma of the extremities are presented. All tumours were hypervascular. Vascular compression was seen in four tumours and intravenous tumour growth could be demonstrated in three. These findings are of great value in the planning of surgical treatment. The importance of securing an optimal venous phase of the examination is emphasized.

Adult↗
PubMed1983

Partial ablation of the kidney by intraarterial ethanol in domestic swine.

Partial renal ablation was produced in 15/17 swine kidneys after segmental intraarterial injection of 1-2 ml of 95% ethanol. Complications were seen in 3 kidneys, including reflux of ethanol into nontarget vessels with subsequent total infarction of 2 kidneys, and the development of hydronephrosis in 1 kidney. Strictly selective catheterization and a very slow injection of ethanol are essential to avoid complications. This technique may find clinical application and the possible indications are discussed.

Animals↗
PubMed1983

Renal artery aneurysms. Natural history and prognosis.

Eighty-three patients out of 8,525 undergoing renal angiography during the years 1970-1979 were found to have renal artery aneurysm, which in six patients were bilateral and in 11 multiple. This corresponds to an incidence of almost 1% in this group of patients. Sixty-nine patients were treated conservatively and followed for a mean of 4.3 years. At that time nine patients had died. The cause of death was in no case related to the aneurysm. None of the 60 living patients had symptoms which could be related to the aneurysm. Reports of 36,656 autopsies, including most of the sudden deaths occurring in southern Sweden during a ten-year period, were analyzed. Nineteen cases of ruptured arterial aneurysms in the branches of abdominal aorta were found, but in no case were the renal arteries involved. It is concluded that the risk for rupture of a renal artery aneurysm is extremely small. The indications to operate renal artery aneurysms are discussed.

Adolescent↗
PubMed1983

Radiologic and clinical evaluation of Harrington instrumentation in the injured dorsolumbar spine.

Conventional radiography and CT examination of the dorsolumbar spine were performed in 9 cases of vertebral fractures before and after Harrington instrumentation. The findings were correlated with neurologic symptoms and signs and the role of a commonly observed retropulsed vertebral body fragment in the development of compression symptoms of the spinal cord or cauda equina is discussed.

Adolescent↗
PubMed1983

Localized primary amyloidosis of the ureter.

A 57-year-old man with a history of right-sided renal colic had a stricture of the right ureter which was suspected to be caused by a tumour or retroperitoneal periureteric fibrosis. Peroperative frozen section examination revealed tumour-forming amyloidosis of the ureter. The right kidney therefore could be salvaged by an end-to-end ureter anastomosis. Although primary amyloidosis of the ureter is rare, it should be included in the differential diagnosis of ureteric strictures.

Amyloidosis↗
PubMed1983

The vertical position of the patella.

A new radiographic method for estimation of the vertical position of the patella in extension is presented. The vertical position of the patella determined by this method and the length of the ligament, patella and its surface were all found to be related to body-height. The vertical position of the patella may thus be expressed as its ratio to body-height: the vertical index of the patella.

Adolescent↗
PubMed1983

Total hip replacement in juvenile chronic arthritis.

Fifty total hip replacements in 33 patients with juvenile chronic arthritis were performed over a 10-year period with good pain reduction, increased hip motion but only a moderate increase in walking capacity. The average age at operation was 26 years and the average follow-up time 77 months. Six hips (patients) have been reoperated, one for infection, one for suspected infection and four due to mechanical loosening. Loosening was revealed radiographically in 10 hips at follow-up. Lack of cement cover and varus position was the main reason for loosening of the femoral stem. Considering the high loosening rate it is probable that at least one revision arthroplasty will be necessary in the future.

Adolescent↗