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Biomedical subjects

L Bossi

Publications and source records attributed to L Bossi.

97 records · Page 6Linked to original sources

[Computerized electroencephalography in acute cerebral ischaemia (author's transl)].

Physiopathological, clinical and therapeutical problems of acute cerebral ischaemia and brain infarction are briefly discussed. In the opinion of the Authors, a first valuable approach to the diagnosis and treatment of these conditions is afforded by the computerized electroencephalography (Berg Fourier Analysis). This investigations proved to be a safe, easy and reliable tool for testing and monitoring the effectiveness of individually selected drugs in early phases of cerebral ischaemia.

Acute Disease↗

[Peduncular hallucinosis in a young woman with vertebrobasilar insufficiency based on severe hypoplasia of a vertebral artery, demonstrated angiographically].

A clinical case of peduncular hallucinosis due to circulatory insufficiency of the cerebral trunk is reported. Angiography revealed marked hypoplasia of a vertebral artery. The patient presented changes to sleep-arousal rhythms and neurological signs with focus involving the cerebral trunk. The patient took an emotional part in her visual hallucinations even though she was aware that they were only hallucinations. A review of the literature on the subject follows.

Adult↗

[Vertebrobasilar insufficiency sustaining grave hypoplasia of the vertebral artery. Report of a clinical case resembling disseminated sclerosis].

The case of a young woman affected by at first paroxysmal and then stabilized disturbances of the pyramidal system and of certain cranial nerves is reported. The case had been diagnosed on several previous occasions as ascribable to demyelinizing disease. Careful study of the vertebrobasilar circulation and of the origin of the large trunks of the aortic arch, highlighted hypoplasia of a vertebral artery. The need to study further the arterial circulation (aortic arch and vertebrobasilar district) in those young patients whose symptoms too obviously point to disseminated sclerosis is pointed out.

Adult↗

[Long-term levodopa syndrome. Report of a clinical case].

Since it is was first described by James Parkinson in 1817 much has been learnt about Parkinson's disease. The complete picture is not clear, however, and a new impulse has been given to the study of the physiopathology of the basal ganglia by the therapeutic employment of L-Dopa with a peripheral inhibitor of the decarboxylase. This treatment is the best available particularly for akinetic-hypertonic forms. In certain cases, however, patients developed a dyskinetic long-term L-Dopa syndrome, depending on the amount of L-Dopa given and individual sensitivity. The syndrome occurs in Parkinsonism only and can be prevented by thalamolysis. It would appear to be a specific expression of the effect of L-Dopa on the striatonigral system rather than of generic hypersensitivity due to denervation. A personal case is presented.

Basal Ganglia↗