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Biomedical subjects

L Ballerini

Publications and source records attributed to L Ballerini.

107 records · Page 6Linked to original sources
PubMed1977

[Echocardiographic aspects of supravalvular aortic stenosis (author's transl)].

Seven patients with hemodynamic and angiocardiographic diagnosis of supravalvular aortic stenosis were studied by single plane echocardiography. 3 patients had the hypoplastic and 3 the "hourglass" type of the disease. 3 patients underwent surgical repair of the malformation, with postoperative echocardiographic control. There was no relationship between the lumen dimension variations as measured by echocardiography and the transtenotic pressure gradient. With respect to angiocardiography, echocardiography underestimates the severity of the disease. The method was always diagnostic, but the anatomic type of stenosis could not be determined. The severity of the disease can be only indirectly assessed by evaluating left ventricular hypertrophy induced by pressure overload.

Adolescent↗
PubMed1976

Effect of adriamycin on the activity of the succinate dehydrogenase-coenzyme Q10 reductase of the rabbit myocardium.

Rabbits were injected with adriamycin 3 days/week/7 weeks. Heart tissues of treated rabbits showed myocardial degeneration, but the tissues of controls were normal. The deficiency in the activity of the succinate dehydrogenase-coenzyme Q10 reductase in the heart tissues of the rabbits treated with adriamycin was higher (0.001 less than P less than 0.01) than that for control tissues. These data indicate a correlation of at least a part of the cardiotoxicity of adriamycin in cancer patients to inhibition of CoQ10-enzymes, since coenzyme Q10 is indispensable to bioenergetics in the myocardium of both humans and rabbit.

Animals↗
PubMedDate not supplied

Patient flow analysis and referrals--how 1,137 ESRD patients started dialysis during 1998-1999.

The study consisted in collecting and analysing data from 15 dialysis centres on referral modalities of 1,137 patients with end-stage renal failure starting renal replacement therapy. All the centres in question had implemented PFA Patient Flow Analysis, a management programme for pre-dialysis care from Baxter designed to help improve the collection of data on dialysis patients, from the first visit to a centre through to the start of renal replacement therapy. The aims of the study were threefold: a) describe patient referral modalities and the eligibility of patients for renal replacement treatment; b) determine how many early referrals (ERs) and late referrals (LRs)* have a permanent PD (Peritoneal Dialysis) or HD (Haemodialysis) access at the first treatment; c) for the main outcomes (permanent access at the first treatment and permanent dialysis treatment), compare the performance of centres that offer enhanced education with those that do not. The main characteristics (sex and age) of ERs (54%) are comparable to those of LRs. However, ERs generally have greater access to PD or the opportunity to choose the dialysis treatment. The vast majority (86%) have permanent access at the first dialysis treatment and a large number (44%) have PD as permanent dialysis treatment. Centres with structured pre-dialysis educational programmes experience a larger number of ERs, therefore ensuring better outcomes. For example, 66.3% of patients at centres with structured pre-dialysis educational programmes (compared to 48.2% at centres without enhanced education) start the dialysis treatment with permanent access; and more patients (40% vs. 22%) receive permanent PD.

Aged↗
PubMedDate not supplied

[Early or late referral patterns of 1137 patients starting dialysis in 15 Italian dialysis centres].

INTRODUCTION: Data on referral patterns of patients with end-stage renal failure starting renal replacement therapy were collected. The participating centres used the PFA Patients Flow Analysis (R) software programme, a Baxter tool designed to help improve data collection on dialysis patients from their first visit to the centre to the start of renal replacement therapy. METHODS: Data were collected on 1137 patients from 15 dialysis centres, mainly in northern Italy, with the aim of describing a) their referral modalities; b) their eligibility to renal replacement treatments; c) the number of early and late referrals utilising a permanent PD (Peritoneal Dialysis) or HD (Haemodialysis) access at the first treatment. RESULTS: Early Referrals (ERs) (54%) are comparable in terms of their main characteristics (sex and age) to Late Referrals (LRs) but they have wider access to a PD or to the opportunity of choosing their dialysis modality. The majority (89%) of all ERs, have a permanent access at the first dialysis treatment and a larger number (44%) have a PD as permanent dialysis treatment. Centres with structured pre-dialysis educational programmes achieve better outcomes: 66.3% patients vs. 48.2% without enhanced education start the dialysis treatment with a permanent access and more patients (40% vs. 22%) receive a permanent PD. CONCLUSIONS: Comparing centres with and without timely structured educational interventions seems to confirm the effectiveness of such education on the outcomes of ESRF patients.

Aged↗
PubMedDate not supplied

Giant left atrium and mitral valve disease: early and late results of surgical treatment in 40 cases.

Forty consecutive patients undergoing mitral valve replacement with a giant left atrium, form the basis of this report. Two groups could be identified: (a) isolated giant left atrium (11 cases); (b) combined left and right atrial enlargement (29 cases). Tricuspid regurgitation was only detected in the latter group. The early hospital mortality was 20% and was related to the pulmonary arterial systolic pressure. A giant left atrium increased the operative mortality from 7% to 20% among patients submitted to mitral valve replacement in our unit (p less than 0.05).

Adolescent↗