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Biomedical subjects

L A Page

Publications and source records attributed to L A Page.

46 records · Page 3Linked to original sources

Comparison of direct and modified direct complement-fixation and agar-gel precipitin methods in detecting chlamydial antibody in wild birds.

Detection of chlamydial antibody in serums of wild birds was compared for the following methods: direct complement-fixation (DCF), modified DCF (MDCF), and agar-gel precipitin (AGP). The birds species used were great-tailed grackles (Cassidix mexicanus), common grackles (Quiscalus quiscula), brown-headed cowbirds (Molothrus ater), bronzed cowbirds (Tangavius aeneus), and mourning doves (Zenaida macroura). The birds were either inoculated with an isolate of Chlamydia psittaci obtained originally from turkeys or kept as uninoculated cagemates. DCF detected antibody in most inoculated common grackles, mourning doves, and brown-headed cowbirds. It was unreliable, however, for great-tailed grackles and bronzed cowbirds inoculated intramuscularly. MDCF method detected antibody in all inoculated birds except 1 mourning dove, and gave higher titers than did DCF. AGP detected antibody in all inoculated brown-headed cowbirds and all mourning doves, 1 inoculated and 1 exposed great-tailed grackle, and none of the other 2 species. Chlamydiae were apparently transmitted to the uninoculated great-tailed and common grackles and mourning doves, for antibody was detected by all 3 methods in these species kept as uninoculated cagemates.

Animal Population Groups↗

Final heights in 45,X Turner's syndrome with spontaneous sexual development. Review of European and American reports.

STUDY OBJECTIVE: To assess the effect of endogenous estrogen secretion on the final heights of patients with 45,X Turner's syndrome. DESIGN: European and American reports of patients with 45,X Turner's syndrome and spontaneous sexual maturation in which final heights were available were analyzed and compared with existing norms for untreated patients with Turner's syndrome. Subgroups of patients were compared as a means of distinguishing low from normal endogenous estrogen exposure, and the effect of the age of menarche was assessed. PATIENTS: Twenty-three cases were collected, including eight who became pregnant. One had full somatic maturation but did not menstruate. RESULTS OF ANALYSES: Mean height of all 23 patients was 140.8 cm +/- 8.07 (s.d.) vs 143.1 cm +/- 6.0 (p = 0.035) for literature norms for Turner's syndrome. Mean height of those who achieved pregnancy was 138.6 cm +/- 8.21 (p = 0.035 vs literature norm); of those with normal gonadotropins 137.5 cm +/- 6.03; and of those with high gonadotropins 139.2 cm +/- 1.44 (p = 0.374). Age of menarche was available in 21 and showed no correlation with final height. CONCLUSIONS: Physiological and subphysiological endogenous secretion of estrogen in Turner's syndrome does not increase final height, suggesting that even low-dose exogenous estrogen would not increase ultimate stature in these patients.

Adolescent↗