Search PubMed⌕ Search

Biomedical subjects

K Yano

Publications and source records attributed to K Yano.

At least 811 records · Page 45Linked to original sources
PubMed1977

Coffee, alcohol and risk of coronary heart disease among Japanese men living in Hawaii.

We examined the relation of coffee and alcohol consumption to the risk of coronary heart disease during a six-year period in a cohort of 7705 Japanese men living in Hawaii. The analysis was based on 294 new cases of coronary heart disease. There was a positive association between coffee intake and risk, but it became statistically insignificant when cigarette smoking was taken into account. There was a strong negative association between moderate alcohol consumption (up to 60 ml per day), mainly from beer, and the risk of nonfatal myocardial infarction and death from coronary heart disease. This association remained significant in multivariate analysis, taking into account smoking and other risk factors. The correlation of alcohol consumption with the level of alpha cholesterol (positive) and beta cholesterol (negative) may partly account for the observed negative association between alcohol and coronary heart disease.

Aged↗
PubMed1975

Left axis deviation and left anterior hemiblock among 8,000 Japanese-American men.

Electrocardiographic patterns of left axis deviation and left anterior hemiblock, defined by a frontal plane QRS axis of minus 30 degrees to minus 44 degrees and minus 45 degrees to minus 90 degrees, respectively, with normal QRS duration, were found to be fairly common (2.6 and 1.5 percent, respectively) in a community population of 8,000 Japanese-American men aged 45 to 69 years. More than 60 percent of men with these electrocardiographic patterns had no other cardiovascular abnormalities, and the incidence of fatal or nonfatal coronary heart disease and stroke in this group during observation periods of 3 to 6 years was not significantly different from that of control normal men. A significant association was found between these electrocardiographic patterns and the prevalence of hypertension, myocardial infarction and stroke. However, the association of myocardial infarction with left anterior hemiblock appeared to be coincidental and was attributed largely to the similarity of the electrocardiographic manifestations of left anterior hemiblock and inferior wall myocardial infarction. Men with left axis deviation were fatter and had higher blood pressure than the control population. No such difference could be demonstrated for men with left anterior hemiblock although this group was significantly older than control subjects and men with left axis deviation. The results of our study suggest that there are qualitative differences between the causative mechanisms and clinical features of left axis deviation and those of left anterior hemiblock.

Age Factors↗
PubMed1975

Recent trends in the mortality rate from renal disease in children and young adults in New York City.

Analysis has shown that the over-all death rate from renal disease for residents of New York City under 25 years of age has declined from 4.6 per 100,000 in 1950 to 2.3 per 100,000 in 1970. Nephritis and nephrosis was the major disease category accounting for this decrease in deaths. A similar trend was found for the United States as a whole. Other causes of renal disease did not manifest consistent changes in death rates. The decline in deaths from nephritis and nephrosis could not be ascribed solely to changing diagnostic habits or terminology. A possible alternative explanation is a change in the natural history of these diseases. Data of this type might be useful as an index to future trends in the mortality rate from renal diseases and as one basis for projections of potential future needs for dialysis and renal transplantation. Using 1965 data, we estimate the number of such potential candidates in New York City would have been 9 per 1,000,000 for the 5 to 14 year age group and 23 per 1,000,000 for the 15 to 24 year age group. There are significant limitations of projections based on such data. These estimates of potential candidates for chronic dialysis or renal transplantation are the first available for children in the United States.

Adolescent↗