[The present state of chemotherapy].
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Biomedical subjects
Publications and source records attributed to K Simon.
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The authors present the first case of congenital toxoplasmosis mimicking a cerebral tumor. Serological reactions and special features of congenital toxoplasmosis relevant to diagnosing in this disease are discussed. Trials to prevent congenital toxoplasmosis as quoted from the literature are reviewed.
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In our sphere of life the picture of tuberculosis has altered. Infections in children have become less severe and considerably rarer. The chronic tuberculosis of age is decreasing. The reasons for the change in the course of tuberculosis are to be found in an increasing power of resistance of the body produced by better social hygienic conditions, a better immunological defense and the institution of modern therapy. Tuberculosis should only be subdivided into primary and post-primary stages with the possibility of spreading through local progressiveness to lymphadenobronchogenic and hematogenic pathways.
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A 41 years old female patient was operated on account of mediastinal tumour. A chondrosarcoma of 10 X 8 X 8 cm was removed. The patient remained symptomfree and had no complaints over 4 years after the operation, but after this relapse and pulmonary metastasis developed. In connection with the demonstrated case the referring literature of mediastinal chondrosarcomas was surveyed and it could be established that this is the twentieth published case about mediastinal chondrosarcoma.
Compared with the adults the child's bloodlevel after having taken Rifampicin is lower, therefore it is recommanded to take a higher dose of 15 mg/kg in the morning before having breakfasted. A combination of doses of 10 mg/kg INH and 20 mg/kg Ethambutol is possible without any doubt. If you consider the reaction which may arise, SGOT and SGPT values up to 21 mU are without any signification. If they depasse this limit a certain control is necessary and if they are still progressive the therapy must be changed. If you compare the experiences with the adults, secondary effects of Rifampicin in childhood are less, just so indigestibleness of the stomach or intestines tract or allergies.