Search PubMed⌕ Search

Biomedical subjects

K Okubo

Publications and source records attributed to K Okubo.

At least 307 records · Page 17Linked to original sources
PubMed1985

Distribution of marker-specific lymphocyte subsets in healthy human subjects.

Cell membrane surface markers on peripheral blood lymphocytes of healthy human subjects were analysed by flow cytometry using monoclonal antibodies. Peripheral blood was obtained from 156 healthy individuals of both sexes, and ages ranging from 2-82 yr. The distribution of the lymphocytes with specific cell markers according to differences in sex and age was calculated. There was a significant difference (p less than 0.05) between sexes in the mean percentages of OKT4+ and OKT8+ cells and in the OKT4/8 ratio while the OKT3+, OKT10+ and OKIa1+ cells, and OKT4/8 ratio clearly correlated with age. A significant correlation among OKT3+, OKT4+, OKT8+, OKT11+ and OKIa1+ cells was obtained, and the results indicated that the percentage of a specific marker-positive cell varied under the influence of other marker-positive cells.

Adolescent↗
PubMed1985

[Autotransfusion].

Explore the source record for details and available documents.

Blood Transfusion, Autologous↗
PubMed1984

[Alteration of peripheral blood lymphocyte subsets in the patients with ovarian cancer before and after chemotherapy].

Peripheral blood lymphocyte subsets of 8 patients with ovarian cancer were analyzed before and after chemotherapy by using monoclonal antibody (OKT series) and laser flow cytometer (Spectrum III). The following results were obtained: There was no significant difference in the distribution of OKT3+ and 11+ cells before and after chemotherapy, and between the patient and the control groups. OKT4+ cells were significantly decreased in number after chemotherapy in the patient group when the results were compared with the control (p less than 0.001) and the pretreatment (p less than 0.05) groups respectively. OKT8+ cells were more markedly increased in number after chemotherapy in the patient group (p less than 0.05) than in the control group. OKIal+ cells were more increased in number after chemotherapy in the patient group (p less than 0.01) than the control group. The OKT4+/OKT8+ ratio in the patient group was significantly decreased after chemotherapy when the value was compared with the control (p less than 0.001) and the pretreatment (p less than 0.05) groups.

Adenocarcinoma, Mucinous↗