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Biomedical subjects

K Motegi

Publications and source records attributed to K Motegi.

At least 91 records · Page 5Linked to original sources
PubMed1989

Congenital midline sinus of the upper lip. Report of a case.

An extremely rare case of congenital midline sinus of the upper lip in a 12-year-old girl is presented. The sinus had a pit-like orifice in the midline philtral area with a duct extending 4 mm posterosuperiorly. It was excised by extraoral elliptical incision. Histopathological examination disclosed that the duct was covered by a stratified squamous epithelium with sebaceous glands. Twelve cases of this rare disease have previously been reported.

Child↗
PubMed1989

Mandibular lesions in patients with adenomatosis coli.

Adenomatosis coli is a very interesting disease accompanied by a number of associated stigmata in the mandible. If left ignored, colonic lesions in patients with this disease proceed almost entirely to malignancy. Hence, detection of the stigmata is very important. The panoramic radiographs of 26 patients diagnosed as adenomatosis coli at the 2nd Department of Surgery, Hamamatsu University School of Medicine from 1978 to 1988 were compared with those of 264 controls. Osteomatous lesions were present in 62% of the patients with adenomatosis coli and 14% of the controls. Pantomographic comparison of the numbers and areas of the osteomatous lesions between the adenomatosis coli and control groups indicated that specific pathognomonic symptoms were demonstrated in panoramic radiographs of approximately 42% of the patients with adenomatosis coli.

Adolescent↗
PubMed1989

[Automated instruments for clinical laboratory--its past and future].

Since the invention of the Autoanalyzer (flow system) by Skeggs in 1953 and Swedish invention of the AGA-Autochemist (discrete system) remarkable developments have been made in the field of clinical laboratory examinations. The Autoanalyzer was improved, from mono-channel to multi-channel, using various methods besides colorimetry, and with the aid of computers, it is now being applied to hematology and immunochemistry as well as chemistry. Although the AGA-Autochemist was something like a chemical factory at the beginning, various instruments using discrete system have been produced according to the refinement of the basic mechanisms of AGA-Autochemist. It is now used in other fields and has contributed considerably to clinical laboratory examinations. This article reviews the development of these instruments at intervals of five years, as reported or reviewed at the scientific meetings of the Japan Society for Clinical Laboratory Automation, and articles of the Journal of the Society. The evaluation of merits and demerits of clinical automation is omitted due to limitation of space.

Autoanalysis↗
PubMed1988

Articular eminectomy for long-standing luxation of the mandible. Report of 2 cases.

2 cases of long-standing luxation of the mandible are presented. Both patients were successfully operated on by articular eminectomy according to Myrhaug's description, with the purpose of both reposition of the condyles and prevention of redislocation. The articular eminectomy increased the ease of reduction and was effective in preventing future dislocation of the temporomandibular joint.

Aged↗
PubMed1988

Cleavage lines of the oral mucosa in Japanese cadavers.

Cleavage lines were experimentally reproduced in the oral mucosa of Japanese cadavers. They were investigated macroscopically and histologically. The reproduced cleavage lines showed little directional variation by sex or age. From the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.

Aged↗
PubMed1987

Pre-auricular (tragus) skin incision in fracture of the malar arch.

The malar arch consists of both the temporal process of the malar bone and the zygomatic process of the temporal bone. So far, there have been various different surgical approaches to the fractured malar arch. This report deals with 16 cases of the facial bone fractures including the malar arch. The usefulness of a pre-auricular (tragus) skin incision elongated to the haired temporal region is presented.

Adolescent↗
PubMed1986

Complete median cleft of the upper lip and alveolus with holoprosencephaly.

A case of complete median cleft of the upper lip and alveolus with holoprosencephaly is presented. An 8-month-old girl was successfully treated by closure of the median upper lip. In addition, 9 patients who have undergone cheiloplasty of complete median cleft of the upper lip with holoprosencephaly reported in the Japanese literature, are reviewed.

Abnormalities, Multiple↗
PubMed1986

Skin incision parallel with skin cleavage lines for access to the fractured zygomatic arch.

In surgery of the fractured zygomatic arch the skin incision was placed parallel with the skin cleavage lines, directly over the zygomatic arch. The fracture site was exposed by blunt dissection of the subcutaneous tissue. Facial palsy may be predicted as a possible sequel to this incision. In fact, facial paresis occurred in 1/3 of the patients but it disappeared within 6 months. It appeared that the facial nerve was only damaged by stretching during the surgical procedure but was not severed by the incision. The postoperative scars presented no unsightly appearance, if the incision was placed completely parallel with the cleavage lines.

Adolescent↗
PubMed1986

Cleavage lines of the skin.

Detailed investigation on cleavage lines over the entire area of the body was undertaken in 3 each of male and female cadavers. The directions of cleavage lines showed sex and individual differences. Minute comparison of the diagrams obtained in this study with earlier diagrams revealed the presence of delicate differences in the directions of cleavage lines. Microscopical evaluation of cleavage lines showed that in the regions where cleavage lines were linearly arranged, collagen fibers were regularly arranged in a uniform direction, conforming to the direction of cleavage lines from the shallow reticular layer immediately below the papillary layers to the inner reticular layer where sebaceous and sweat glands existed and that in the regions where cleavage lines were ramified, collagen fibers in these layers lacked directional regularity. The morphology of cleavage lines were considered most influenced by collagen fibers in the epidermal reticular layers from their shallow layers immediately below the papillary layers to the layer where sebaceous and sweat glands existed.

Adult↗
PubMed1986

Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man.

The pharmacokinetics of coenzyme Q10 (CoQ10) in man was studied by utilizing deuterium-labelled coenzyme Q10 (d5-CoQ10). The absence of an isotope effect in the disposition of d5-CoQ10 in man was confirmed from the plasma concentration time curves after simultaneous oral dosing of d5-CoQ10 and unlabelled CoQ10. After oral administration of 100 mg of d5-CoQ10 to 16 healthy male subjects, the mean plasma CoQ10 level attained a peak of 1.004 +/- 0.370 micrograms/ml at 6.5 +/- 1.5 h after administration, and the terminal elimination half-life was 33.19 +/- 5.32 h. In most of the subjects, plasma d5-CoQ10 showed a second peak at 24 h after dosing. This unusual plasma level curve was well described by a newly proposed compartment model based upon the assumption that absorbed CoQ10 is taken up by the liver and then transferred mainly to VLDL and redistributed from the liver to the systemic blood.

Administration, Oral↗
PubMed1985

Blow-out fracture of the orbit in 4 children.

4 cases of blow-out fractures of the orbit in children are presented. Four 6- to 12-year-old boys were successfully operated on via an orbital and transsinus approach. As material for restoration of the broken orbital floor, Silastic was used in 3 patients.

Child↗
PubMed1985

The relation between cleavage lines and postoperative scars after repair of cleft lip.

The "rotation-advancement method" was used for primary repair of the incomplete cleft lip in six infants. The skin cleavage lines were visualized using the tissue ablated in the operation. On examining the relation between the post-cheiloplasty scar formation and the direction of the cleavage lines, the scar remained less conspicuous where the incisions parallelled the cleavage lines but grew hypertrophic where the incisions crossed the cleavage lines.

Cicatrix↗