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Biomedical subjects

K Minami

Publications and source records attributed to K Minami.

At least 397 records · Page 22Linked to original sources
PubMed1977

Solar uticaria. Photoallergen in a patient's serum.

A 45-year-old man had solar urticaria that was activated by visible light. Passive transfer of the reactivity with the patient's serum to the skin of normal recipients was accomplished. Results of reverse passive transfer studies were negative. The patient developed an urticarial wheal at the site of injection of his own serum that had been previously exposed to light in vitro. The experimental data suggested that his condition was attributable to an allergic response. Systemic administration of reserpine was of some therapeutic value, and increasing exposure to natural sunlight was associated with substantial in crease in his tolerance to sunlight. Unfortunately, the possible loss of reactivity that may occur in the natural course of the disease makes substantiation of the therapeutic effects difficult.

Allergens↗
PubMed1977

A case of chromomycosis treated with 5-fluorocytosine.

A 46-year-old housewife was treated orally with 5-fluorocytosine (5-FC). She was almost cured at 15 weeks after the administration. Under histological and electron microscopical examination, spores in the lesions were observed to be markedly decreased in number, and all of them had suffered a change of shape or had been destroyed. At the end of 33 weeks, however, the patient had a complete relapse.

Administration, Oral↗
PubMed1977

Trichophytin contact sensitivity in patients with dermatophytosis.

Trichophytin contact sensitivity was investigated in patients with dermatophytosis by patch testing with highly concentrated purified trichophytin on partially stripped skin. The lack of primary irritant reactions was confirmed on the skin of children. Positive patch tests were noted in 113 of 178 patients (63.5%). However, there was a great difference in the incidence of trichophytin contact sensitivity between cases with different clinical types. The highest frequency of positive patch tests was obtained in patients with the vesiculobullous type of tinea pedis (83.3%). In contrast, a very low incidence was noted in patients with tinea corporis (37%) and the squamous hyperkeratotic type of tinea pedis (36%). Causative organisms and the age and sex of the patients did not show a relationship with the reactivity. A diminished incidence of positive reactions was noted in atopic individuals and in patients seen in winter. Patients who had persistent or recurrent infections for a long period of time, especially those having inflammatory lesions, had a higher frequency of positive patch tests.

Adolescent↗
PubMed1976

An epidemic of acute hemorrhagic conjunctivitis in Sendai area, 1973-1974.

In 1973 and 1974, an epidemic of acute hemorrhagic conjunctivitis (AHC) with a tendency of less frequent conjunctival hemorrhage occurred among the staff of the National Railways and their family in Sendai area. Four strains of AHC virus and 4 strains, 1 of type 7 and 3 of type 8, of adenoviruses were isolated from 22 conjunctival swabs of the patients. Thirty-six (66%) out of 55 cases examined were proved serologically to be of AHC virus infection, and 7 cases (13%) were of adenovirus infection. Clinically, infrequent association of hemorrhagic conjunctivitis was most remarkable. Only 10 cases (28%) had detectable signs of hemorrhagic conjunctivitis. There were no substantial changes in antigenicity and optimum temperature for virus multiplication between prototype and isolated strains. The isolated strains, however, seemed to be less neutralizable and less producible at 29 degrees C than prototype strain.

Acute Disease↗