[Clinical-pathogenetic classification of Q fever].
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Biomedical subjects
Publications and source records attributed to K M Loban.
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The high incidence of malaria in Ethiopia is due to a number of natural and social factors. The 1988-1989 surveys of 525 patients among this country's indigenous population showed that its great proportion suffered from severe falciparum malaria, including that caused by the chloroquine-resistant strains Plasmodium falciparum. The severity of falciparum malaria seems to be determined by the low immunity of inhabitants in the hyperendemic areas and by late effective therapy. The lack of antimalarial drugs alternative to chloroquine will facilitate fatal malignant malaria.
In the hyperendemic areas of Ethiopia there is severe tropical malaria, "cerebral malaria" which is frequently followed by complications as malaria coma or malaria algide. The authors followed up the clinical course and causes of malaria coma in 25 patients, including in 10 dead subjects. The development of malaria coma is chiefly associated with untimely diagnosis, patients' late admissions, and inadequate prehospital treatment. The current and past diseases may be regarded as factors aggravating the disease.