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Biomedical subjects

K M Loban

Publications and source records attributed to K M Loban.

At least 19 recordsLinked to original sources
PubMed1988

[Clinico-laboratory and morphologic characteristics of the tropical splenomegaly syndrome].

A follow-up of 142 patients with the syndrome of tropical splenomegaly in Mulago Hospital in Uganda made it possible to study a clinical course, the informative value of hematological, some biochemical and immunological indices, morphological changes of liver biopsy specimens in this syndrome. Over a 10-year period 9020 autopsy records were studied for comparative assessment of a histological picture and causes of death in Mulago Hospital. The syndrome of tropical splenomegaly was diagnosed in 88 (0.98%) of them. The main diagnostic criteria were proposed for this pathology. This pathology should be denoted as the syndrome of tropical splenohepatomegaly.

Biopsy↗
PubMed1987

[Treatment of imported tropical malaria caused by chloroquine-resistant strains of P. falciparum].

The chloroquine-resistant strains P. falciparum are widely spread in the countries of South-East Asia, Latin America. Since the middle of the 70s the strains also occurred in Eastern Africa. The given paper is concerned with 4 patients suffering from imported chloroquine-resistant tropical malaria. Of these, 3 patients come from Africa, and one from Vietnam. In the latter patient, the disease ran a grave course and was attended by coma, acute renal insufficiency, hepatitis, and hemolytic anemia. The patient was registered as having grade III resistance of P. falciparum to chloroquine. The schedules of the disease treatment including quinine with fansidar, metakelphin (or with sulphalene and chloridine), mafloquine or tetracycline are presented.

Adolescent↗
PubMed1978

[Stimulating effect of prodigiozan on nonspecific reactivity in typhoid fever, dysentery and staphylococcal infection].

A number of factors of nonspecific reactivity, i.e. complement, lysozyme, properdin, blood serum bactericidal activity, leucocyte phagocytal activity, phagocytal index and completed phagocytosis were studied on 160 guinea pigs with experimental typhoid fever, dysentery and staphylococcal infections. The data of the study showed that with the use of prodigiozan the non-specific reactivity of the host increased even within a short period of time. At the same time the pathological changes in the internal organs in their histochemical investigation decreased.

Animals↗
PubMed1977

[Morphological changes in experimental infection in guinea pigs under the influence of prodigiozan and S-methylmethionine].

The effect of prodigiozan and S-methylmethionine on the level of histomorphological changes in the organs and tissues of guinea pigs with experimental typhoid fever, dysentery and staphylococcal infections, as well as the effect of prednizolone with respect to dysentery and staphylococcal infections were studied. In the control animals the highest histomorphological changes were observed on the 4th day after the infection in the liver, kidneys and spleen. In the animals with staphylococcal infection such changes were also observed in the lung tissue. In the animals treated with prodigiozan or S-methylmethionine in a dose of 20 mg or 0.3 ml of a 5 per cent solution respectively simultaneously with or 2 days after the infection the changes in the organs were less pronounced than those in the control. Under the effect of prednizolone used in a dose of 10 mg according to the same schedule the inflammatory-dystrophic changes in the internal organs of the animals with dysentery and staphylococcal infections were much higher as compared to the control.

Animals↗