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Biomedical subjects

K M Jain

Publications and source records attributed to K M Jain.

At least 19 recordsLinked to original sources
PubMed1998

Axillobifemoral bypass: elective versus emergent operation.

Axillobifemoral bypass (AxBFB) is considered an inferior operation because of comparatively poor long-term results. One factor that has not been considered in the literature is whether or not the operation is performed electively or for acute ischemia (< 24 hours duration). This may be a more important predictor of poor results than previously recognized. During the last 10 years, we have performed 59 AxBFB. In Group A, 41 patients (mean age 71) underwent elective AxBFB and in Group B, 18 patients (mean age 65) had emergency AxBFB. Indications for surgery in Group A were limb-threatening ischemia (30), infected aortic graft (5), and severe claudication (6); in Group B, indications for surgery were acute limb ischemia (16), and aortoduodenal fistula (2). Primary patency (p < 0.002), limb salvage (p < 0.002), and survival (p < 0.03) were significantly better in Group A versus Group B. We conclude that an AxBFB performed electively provides satisfactory palliation of severe vascular disease in high-risk patients. The indications for operation and timing of the operation may explain the widely disparate clinical results reported in the literature.

Adult↗
PubMed1996

Vascular operations in nonagenarians.

This is a retrospective study describing our experience with vascular surgical procedures performed in patients 90 years of age or older. Thirty-four procedures, including major and minor vascular reconstruction and amputation, were performed in 20 patients. The 30-day mortality rate was 6% for planned surgical procedures. The 24-month survival rate was 82% for elective major revascularizations and limb salvage was 80% in these patients. We believe that vascular reconstruction can be carried out with acceptable morbidity and mortality when the operations are planned and the patients have been chosen carefully.

Age Factors↗
PubMed1996

Long-term follow-up of bypasses to the brachial artery across the shoulder joint.

BACKGROUND: Most atherosclerotic lesions in the subclavian artery are successfully treated with carotid to subclavian bypass. The need to bypass to the brachial artery (BA) is rare. We reviewed our experience with this bypass. METHODS: Over a 10-year period, we have performed 13 bypasses to the BA originating from an artery proximal to the shoulder joint. In this retrospective study, the demographic and clinical risk factors were evaluated. Long-term results were analyzed. RESULTS: Thirteen operations were performed in 10 patients, aged 47 to 80 years. The operations were carried out for acute severe ischemia in 1 limb, effort discomfort in 9, and rest pain in 3 limbs. Donor arteries were axillary (7), carotid (4), and subclavian (2). All bypasses were to the BA proximal to the elbow joints. Life-table analysis showed 100% patency in the first 3 years and 88% at 7 years. There were 2 deaths in follow-up. Average preoperative brachial to brachial index was 0.59 and postoperative index was 1.1. In patients with bilateral occlusions, mean preoperative brachial artery pressure was 62 mm Hg, which improved to 142 mm Hg postoperatively. There were no neurological complications and no 30-day mortality. CONCLUSIONS: Bypass across the shoulder joint to the BA using expanded polytetrafluoroethylene (ePTFE) or vein is a safe operation with excellent long-term patency. The carotid artery can be used as a donor vessel without complications. Hypertension and female gender appear to be risk factors for extensive disease in proximal upper extremity arteries.

Aged↗
PubMed1995

Aortoiliac bypass in a renal transplant patient using a new technique.

There are only 18 patients described in the English literature who had a preexisting renal transplant and underwent aortic surgery for aortoiliac occlusive disease. We describe an additional patient who was treated with a new technique using a Sundt shunt and a GraftAssist. This technique provides antegrade flow and minimal ischemic time and avoids exploration of arteries not involved in the anastomosis.

Anastomosis, Surgical↗
PubMed1995

Improvement in suction catheter efficiency and safety in arterial operations.

The Blood Shield is a new device which has been developed to attach easily to the tip of a conventional suction catheter. Two experiments were performed to determine if the Blood Shield could limit the degree of splash which occurs during vascular graft flushing and whether it could increase the efficiency of a standard suction tip in collecting shed blood for autotransfusion. The results of the experiments indicate that the Blood Shield, when added to a conventional suction catheter, diminishes the amount of spray which may occur during anastomotic flushing. Secondly, it more effectively collects blood from a flushed anastomosis or arteriotomy in comparison with a suction catheter alone.

Anastomosis, Surgical↗
PubMed1994

Routine completion study during carotid endarterectomy is not necessary.

The results of many studies have suggested the need for a completion study during carotid endarterectomy (CE). This paper describes our experience not routinely using completion studies. We retrospectively reviewed the charts of 417 patients who underwent 455 CEs. Demographic features, risk factors, ipsilateral neurologic events during the first 30 days, and mortality data were identified. There were 14 neurologic events and 4 deaths. No technical defects were found in 13 patients; 1 patient did not have exploratory surgery after an occlusion. Long-term follow-up shows 10 of the 14 arteries are open. Two patients were lost to follow-up, 1 patient died, and 1 artery was not explored. We conclude that CE may be carried out without routinely using a completion study, with an acceptable postoperative neurologic complication rate. Careful technique is mandatory.

Aged↗
PubMed1992

Cross-over bypass to axillary vein in haemodialysis patients.

Two patients are described in whom cross-over bypass to axillary vein was performed to salvage brachio-basilic grafts. Both patients had massively swollen arms because of subclavian vein thrombosis and functioning grafts. Their grafts were used for prolonged periods after the corrective operation.

Arteriovenous Shunt, Surgical↗
PubMed1992

A new technique to correct vascular steal secondary to hemodialysis grafts.

Three patients are described who developed symptomatic steal distal to hemodialysis grafts, documented by angiodynography. Intraoperatively, the graft was plicated to increasing depths while using angiodynography over the radial and ulnar artery. When the flow became antegrade, the plication was stopped, resulting in salvageable grafts. Using the technique, all three patients had long use of the graft after the steal was corrected.

Arm↗
PubMed1985

Hemodynamics of an anastomotic arteriovenous fistula.

Various vascular surgical techniques have been employed to increase both graft patency and limb survival when the prognosis for limb salvage in arteriosclerotic patients is especially poor due to a diseased outflow tract. Ibrahim et al described the creation of an anastomotic arteriovenous fistula in distal tibial bypasses as the reconstructive procedure of choice in severely ischemic extremities unsalvageable by more conventional methods. This study presents the hemodynamics of an anastomotic arteriovenous fistula under such circumstances. Four adult mongrel dogs were anesthesized, and a femoral artery and vein were exposed from the groin to the knee. The femoral artery was ligated in midthigh, and the ligated segment was than bypassed using an umbilical vein graft. The distal anastomosis included an arteriovenous fistula. Flow was measured electromagnetically, and pressure was measured with intravascular catheters attached to strain gauges. The creation of an anastomotic arteriovenous fistula rapidly leads to a reversal of flow in the distal artery, distal arterial hypotension, and distal venous hypertension. Its clinical use in contraindicated as a result of our experimental observations.

Animals↗
PubMed1985

Preoperative cardiac screening before peripheral vascular operations.

Myocardial infarction continues to be a major cause of morbidity and mortality after peripheral vascular operations. In this study, radionuclide angiography (RNA) of the heart was used to delineate the cardiac risk. In 78 patients, there were 53 abnormal RNA studies. Twenty-seven patients with abnormal RNA underwent coronary angiography. Six aortocoronary bypasses were performed prior to or in conjunction with the vascular operation without complications. Ninety major operations were carried out in these 78 patients. There was no myocardial infarction in patients with normal RNA. There were two postoperative fatal myocardial infarctions in patients with abnormal RNA giving a procedure mortality of 2.2 per cent. In 11 patients, the proposed operation was changed. Thirteen patients with abnormal RNA had no cardiac symptoms. Three patients in this subgroup underwent aortocoronary bypass. It was concluded that RNA can effectively identify the cardiac risk in patients undergoing peripheral vascular operations. Routine coronary angiography may be unnecessary as patients with normal RNA have minimal risk of myocardial infarction.

Aged↗
PubMed1985

Effects of vasopressin on cardiac output and its distribution in the subhuman primate.

The effects of vasopressin, when administered as intravenous bolus injections and infusions, on cardiac output and the distribution of blood flow to the splanchnic vascular beds were studied in six anesthetized rhesus monkeys. Vasopressin as bolus injections caused dose-dependent decreases in superior mesenteric arterial blood flow. However, small reductions in cardiac output were observed only at the highest doses concomitant with increases in systemic arterial pressure. When vasopressin was infused at the highest dose (5 X 10(-2) units kg-1 min-1) for 10 minutes, cardiac output was unaffected; but sustained reductions in superior mesenteric arterial blood flow and increases in arterial pressure and total peripheral resistance were observed. Infusions of vasopressin (5 X 10(-3) units kg-1 min-1) caused significant and sustained reductions in superior mesenteric arterial blood flow and increases in arterial pressure but no measurable effects on cardiac output or total peripheral resistance. However, there was a significant redistribution of blood flow away from the stomach, small and large intestines, spleen, and pancreas toward the liver (hepatic artery), with no statistically significant change in renal blood flow. On the assumption that comparable responses exist among primates, these data support the clinical use of vasopressin to control gastrointestinal hemorrhage and to offer a probably ideal dose and route of administration.

Animals↗
PubMed1984

Thrombectomy of a Hemasite graft.

Hemasite is a new device incorporated in a graft that is used for hemodialysis. A technique of thrombectomizing this device incorporated graft is described.

Arm↗
PubMed1984

The Hemasite-incorporated graft. Operative technique and early results.

A new device (the Hemasite-incorporated graft), has been available to provide access for hemodialysis. Herein, we have described the technique to insert the device and reviewed our early experience. Sixteen Hemasite-incorporated grafts were inserted in 11 patients over a 16 month period. Cumulative functional patency at the end of 1 year was 70 percent. The major complication rate was 0.15 per dialysis month. Patient comfort was considerably increased compared with what was achieved with other grafts. The need for temporary blood access methods is also decreased. More patients may be able to receive hemodialysis at home.

Adult↗
PubMed1983

Traumatic aorto-caval fistula.

Trauma is an unusual cause of fistula formation between the aorta and the inferior vena cava. Two cases of traumatic aorto-caval fistula treated at the New Jersey Medical School affiliated hospitals are presented and the literature on traumatic aorto-caval fistula reviewed. We found 14 previously reported cases. Delayed repair was performed in 12 (86%). Delays ranged from 5 days to 12 years postinjury. Cardiac decompensation, judged either clinically or by cardiomegaly evident on chest X-ray, was present in 75% of the patients undergoing delayed repair. The techniques available for repair and the criteria for utilizing delayed repair are discussed. In young, previously healthy patients, usually with smaller fistulae, we conclude that delayed repair can be used.

Adult↗