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Biomedical subjects

K Lackner

Publications and source records attributed to K Lackner.

At least 199 records · Page 11Linked to original sources

[Value of computer tomographic determination of spleen size for the elucidation of splenic involvement within the framework of primary lymph node neoplasms].

The splenic index was determined in 155 persons, without evidence of splenic disease, in order to obtain a simple measure of splenic size. Subsequently 36 patients with malignant lymphomas and who then had their spleens removed were examined by CT. A comparison of the CT and pathological-anatomical findings showed that it is a valuable non-invasive method for diagnosing splenic involvement, having a specificity of 86%, sensitivity of 77% and accuracy of 83%.

Adolescent↗

[Quantification of vascular stenoses using digital subtraction angiography].

Experimental studies using vessel phantoms with varying stenoses have been carried out and a method has been developed for quantitative analysis of vascular stenoses using DSA. The digital information provides quantitative measurements of the amount of contrast within a vessel. The relative contrast density in the region of interest is measured by video densitometry and is proportional to the transverse area of the vessel. The relative densities in and proximal to the stenosis provides a quantitative measure of the relative degree of stenosis. The standard deviation does not exceed 7.5%.

Angiography↗

[Cavography in the digital subtraction technic].

Experience with 74 patients has shown that digital subtraction angiography is a suitable method for the demonstration of the vena cava. In 28 patients the examination was repeated by the conventional large film angiography procedure, but this added no significant information to help to solve the clinical problem. Electronic contrast enhancement permits lower concentrations of contrast to be used than for conventional techniques. Combined with a more selective use of films, this leads to a reduction in the cost of the examination.

Humans↗

Value and limits of the computed tomography of the heart.

In cardiac diagnosis we can observe an increasing replacement of the conventional invasive examination methods by less invasive or non invasive procedures. Non invasive examination methods are sufficient in the diagnostic work-up of ventricular function in coronary heart disease and cardiomyopathie, cardiac tumours and thrombi, calcifications, assessment of the bypass perfusion, pericardial disease, positional anomalies of the heart and the morphological changes caused by congenital cardiovascular defects. Invasive angiocardiography remains essential in the diagnosis of coronary artery stenoses, abnormal bypass perfusion, septal defects and in congenital cardiovascular defects in combination with intracardiac measurements of pressure and oxygenation.

Angiocardiography↗

[Indications and results of portal shunt surgery].

Bleeding esophageal varices are treated in the first line as emergency by sclerosing procedures. Later on shunt surgery is still to be considered as an important definite procedure. Criteria to be met before surgery are discussed. In our experience the shunting procedure as described by Warren yields good results, low incidence of thrombosis and low lethality. In special cases subtotal esophagectomy can be performed, lethality being as low as after the Warren shunt. Repeating sclerosing over years in contrast carries a high risk of complications and death and does not prevent further bleeding safely enough.

Adult↗

[Computed tomography and the clinical picture of carcinoma of the uterine cervix].

The clinical and computer tomographic findings in 142 patients with carcinoma of the body of the uterus have been compared. The CT findings at the first examination were then compared with the clinical results. The likelihood of a recurrence was related to infiltration of the parametrium. There was strong positive correlation between the CT findings during treatment and the probability of recurrences. The wealth of information provided by computed tomography makes any other form of investigation during tumour staging and during follow-up unnecessary.

Bone Neoplasms↗

[Computed tomographic findings in portal hypertension secondary to liver cirrhosis. 3. Hemodynamic changes--angio-CT].

Contrast injection for angio-CT shows kinetic changes in patients with portal hypertension due to cirrhosis of the liver when compared with normals. Contrast-duration diagrams show a higher aortic peak, low contrast and delayed contrast maximum in the liver and portal vein in patients with liver cirrhosis and portal hypertension. On these criteria it is possible to distinguish patients with cirrhosis (n = 18) from normals (n = 16).

Hemodynamics↗

[Accuracy in the diagnosis of renal masses. Computed tomography, sonography, urography, angiography].

One hundred and twelve renal masses, whose histology was confirmed at operation, as well as renal vein thrombosis and renal infiltration, were examined by urography, sonography, CT and angiography. In general the results showed good agreement. For the diagnosis of the type of tumour, its size, infiltration into the renal capsule, demonstration of regional lymph node metastases and infiltration into neighbouring organs and for the diagnosis of liver metastases, CT was superior to the other methods.

Abscess↗

[Digital subtraction angiography of the lung].

DSA of the lung entails reduced examination risk and is a simpler procedure than conventional angiography. Out of a total of 55 lung DSA's, 53 (96%) supplied reliable diagnostic information. Suspicion of pulmonary embolism was the most frequent indication. DSA was also successfully employed in therapy control. Since other diseases of the pulmonary vessels can also be diagnosed via DSA, it can largely replace conventional pulmonary angiography. Disadvantages of DSA which must be taken into consideration are the reduced local resolution and limitations imposed by artifacts caused by patients movements.

Adult↗

[Intravenous digital subtraction angiography (i.v. DSA) of the leg arteries using a movable table].

Sixty-three I.V. DSA examinations of the lower limbs, using a movable table top, are reported. In 92% the examination was adequate. The amount of contrast required for each examination was reduced by having the movable table top. In 8% the examination was inadequate because of increased circulation time, movement of the patient during table top travel or reduced blood flow through severe or long stenoses.

Adult↗

[Anatomic resolution of intra-arterial digital subtraction angiography of the kidney using different concentrations of contrast media].

In 40 patients in whom intra-arterial DSA of the kidney was carried out, the appearance of the vessels was compared between group A (20 patients) in whom 5 ml. of Iopamidol 300 mg. I./ml. and 5 ml. Iopamidol 150 mg. I./ml. were used, with group B (20 patients) in whom 5 ml. Iopamidol 300 mg. I./ml. and 10 ml. Iopamidol 150 mg. I./ml. were used. Apart from the well known advantages of intra-arterial DSA, no improvement was brought about by using lower concentration of contrast.

Angiography↗

[Computed tomographic control of the conventional x-ray findings in space-occupying lesions of the bony pelvis].

The CT and conventional radiological findings in 30 patients with space-occupying lesions of the pelvic bones were compared. 73% of the tumours diagnosed by CT were shown by conventional means and in 71% their extent was correctly estimated. Lesions at the ilio-sacral junction are not demonstrated as well by conventional methods as those near the hip joint. The lesions most frequently missed by conventional radiography lie in the dorsal part of the ilium and in the lateral mass of the sacrum.

Adolescent↗

[Asbestosis. Computed tomography in comparison with conventional roentgen diagnosis].

Thirty patients (27 men and 3 women) with an average industrial asbestos exposure of 19 years have been examined. The results of conventional radiography and CT have been analysed and compared with pulmonary function studies. The advantages of CT depend on a better demonstration of the pleura and lung periphery. In 24% of cases plaques were diagnosed by chest x-rays which could, however, be excluded by computed tomography. Correct prediction of restricted ventilation was possible in 84% patients by means of CT. On the other hand, this prediction by means of conventional radiographs could be made reliably only if there was extensive fibrosis.

Adult↗

[Adverse reactions following high-dose intravenous injection of urographic contrast media].

The frequency and type of side effects from high-dose renographic contrast media correspond with those quoted in the literature for injections of small doses of contrast. In addition to the usual contra-indications against injection of renographic contrast, one should also consider the effect of short-lived increase in circulating volume in patients with left heart insufficiency.

Adolescent↗

[Comparison of intra-arterial digital subtraction angiography with conventional arteriography].

Conventional arteriography and intra-arterial DSA were compared in 243 individuals for examination of the liver, kidney, lower extremity and portal vein. There was no significant difference in the diagnostic value of these methods. DSA suffers from a poorer spatial resolution in the periphery of vessels, but this has not resulted in a loss of clinically relevant information.

Analog-Digital Conversion↗

[Improvement of image quality in digital subtraction angiography using a variable aperture].

The authors examine by means of comparative series in 25 patients whether and to what extent a special combination of filter diaphragms can improve imaging in digital subtraction angiography. It was found that the filter diaphragm combination should be applied as a matter of principle in case of large absorption differences in the examined region, since this will safely eliminate saturation effects causing artifacts, or partial image losses which are otherwise likely to occur. However, no essential advantages are obtained if the x-ray image is largely homogeneous.

Angiography↗

[High resolution computer tomography of the middle and inner ear].

High-resolution CT enables exact visualisation of the bony structures of the petrous bone; at the same time, all relevant nerval, vascular and muscular elements of the middle and inner ear are visualised. A wider range of findings can be attained in this region of wide differences in density than via conventional pluridirectional tomography. The normal anatomy of the petrous bone is demonstrated via CT series of slices in axial and coronal projection.

Ear Diseases↗