[Cryosurgery of carcinoma of the bladder].
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Biomedical subjects
Publications and source records attributed to K Korth.
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A case of a successful percutaneous reanastomosis of a transplanted kidney is reported. The kidney had already been operated on several times. The kidney-ureter anastomosis was occluded. Using a combination of ureteroscopy and the percutaneous technique, the old anastomosis was bypassed and a new one was made.
The indication for and technique of the percutaneous operation of strictures at the ureteropelvic junction in 117 patients are discussed. The results in 66 followed up cases are presented in detail. The new method was found superior to open surgery in cases of secondary (acquired) stenoses and a success rate of 89% can be expected. The results of its use for congenital stenoses are not as good (73%), however, if this simple and safe technique does fail, open plastic surgery can still be performed.
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The technique of puncture and dilatation 'in the hands of one' is described in detail based on almost 800 percutaneous operations on the kidney. All of the steps of the operation were carried out by the urologist himself. The advantages are presented and two new percutaneous instruments are introduced: a percutaneous working sheath and the lumbotome, a wire-guided, double-blade knife for cutting the percutaneous tract. The principle of percutaneous stone operation is explained as well as special complications which can occur. Finally, statistic results are discussed which clearly show a remarkable decrease of the residual and recurrent stone rate in comparison to conventional kidney stone surgery.
Based on results of more than 700 percutaneous renal operations, the performance of both puncture and dilatation by the same urologist is described in detail, as successive steps. Advantages of this method are outlined and two new instruments presented: a percutaneous working sheath and a lombotome guided by a guide-wire and possessing a double blade.
The technique of puncture and dilatation "in the hands of one" is described in detail based on over 800 percutaneous operations on the kidney. All of the steps of the operation were carried out by the urologist himself. The advantages are presented and two new percutaneous instruments are introduced: a percutaneous working sheath and the lumbotome, a wire-guided, double blade knife for cutting the percutaneous tract.
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The results of Farnsworth-Munsell 100-hue, visual acuity, and visual field testing were compared with the severity of retinopathy in a group of 90 diabetic patients. The patients showed significantly higher than expected Farnsworth-Munsell 100-hue scores, with a tritanlike axis, compared with published age norms for nondiabetic individuals. The magnitude of the acquired blue-yellow hue discrimination defect correlated significantly and to a similar extent with both the severity of overall diabetic retinopathy and the severity of macular edema and hard exudate formation. Visual acuity loss correlated somewhat more significantly with macular edema than with overall retinopathy, whereas the converse was true for visual fields. For all visual function tests, the correlations were more significant for fluorescein leakage in the macula than for capillary nonperfusion in the macula. Abnormal hue discrimination was found in 65% (32/49) of eyes with proliferative diabetic retinopathy, suggesting a potential role for this test in screening for proliferative diabetic retinopathy in primary care facilities. Also, because the ability of diabetic patients with color vision deficiency to perform color-dependent tests for urinary and blood glucose may be impaired, such patients should be made aware of this potential problem.
A new ureteral loop is introduced that, in contrast to other loops, allows the kidney to be drained continuously during stone retrieval. Thus, complications caused by blockage of the ureter by the stone, such as fever and colic pain, are avoided. The basket shape of the loop provides optimum grasping of the ureteral stone.
The dimensions of the foveal avascular zone (FAZ) were measured in fluorescein angiograms from 36 diabetic patients and 20 nondiabetic controls. The median values for longest diameter, mean diameter, and circumference were significantly greater in the diabetic group than in the control group. Longest diameters greater than 1.0 mm were found almost exclusively in eyes with proliferative diabetic retinopathy. The FAZ dimensions were strongly positively correlated with the severity of capillary nonperfusion in the posterior retina, but not with fluorescein leakage. The presence of proliferative diabetic retinopathy was also strongly correlated with capillary nonperfusion. Retinal capillary occlusion as the cause of FAZ enlargement in diabetic retinopathy is supported by these findings.
The oscillatory potential (OP) amplitudes of the electroretinogram (ERG) were determined in a group of 85 diabetic patients entering the Early Treatment Diabetic Retinopathy Study (ETDRS). The rate of progression among nonphotocoagulated eyes to the Diabetic Retinopathy Study high-risk characteristics (DRS-HRC) during a ten- to 40-month follow-up period was determined. Progression occurred in 19 of 85 eyes at risk. Those eyes with abnormal OP amplitudes (less than or equal to 75 microV) at study entry had a tenfold higher rate of progression to DRS-HRC than did eyes with normal amplitudes (greater than 75 microV). Although the level of retinopathic severity at study entry was a significant factor in the rate of subsequent progression, the amplitudes of the OPs remained a significant risk factor even after correcting the initial retinopathic level. The ERG seems to be a useful clinical tool in predicting the rate of progression of diabetic retinopathy. The reduction in OP amplitudes probably is a quantitative measure of the degree of overall inner layer retinal ischemia.
The performance of two urinary glucose tests (Clinitest and Diastix) and several color vision and lightness discrimination tests was assessed in 43 diabetic patients and 43 age-matched controls. Most of the diabetics had proliferative diabetic retinopathy, with normal or mildly reduced visual acuity. The diabetics made significantly more errors on color interpretation of the urinary test results than did controls. The extent of errors for both diabetics and controls correlated with the severity of color vision deficiency but not with lightness discrimination deficiency. The diabetics' performance of the Clinitest test and, to a lesser extent, of the Diastix test was significantly better in bright light than in dimmer light. The type of color vision deficiency among most of the diabetics was characteristic of the acquired blue-yellow defect associated with diabetes mellitus. All of the color vision tests enabled identification of patients likely to make a large number of urine-testing errors with high sensitivity and fairly high specificity.
After 2 1/2 years experience with percutaneous surgery on 400 kidneys the limits of this new form of endourology are outlined. These are high ureteral stones which can be visualized only by using the flexible fiberscope and the staghorn stones branched into many calyces. The operating technique and the results are discussed. New frontiers of percutaneous surgical possibilities are shown such as incision of strictures at the ureteropelvic junction, resection of urothelial tumors and marsupialization of renal cysts.
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A new percutaneous pyeloscope for the destruction of kidney stones is presented which is based on the continuous flow principle through a double sheath similar to the resectoscopes. The visibility is always good and complications due to high pressure are prevented.
The introduction of a new sight urethrotome with permanent suction now makes a continuous rinsing stream possible. A sight improvement similar to that of the suction resectoscope is achieved and complications common to the transurethral resection syndrome are reduced.
The simultaneous determination of acid phosphatase and citrate concentration in the seminal fluid obtained from 16 patients with prostatic adenoma showed normal values, 6 patiients with prostatic carcinoma (cytologically and histologically verified) however extremely low values. The difference between persons with prostatic cancer and those with adenoma became particulary obvious with both experimental results evaluated in the way of a twodimensional diagram. This clear separation of both clusters by the simultaneouse estimation of both biochemical parameters may possible get useful diagnostic significance.