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Biomedical subjects

K Kauppinen

Publications and source records attributed to K Kauppinen.

At least 37 records · Page 2Linked to original sources
PubMed1984

Urticaria in children. Retrospective evaluation and follow-up.

A retrospective study supplemented with follow-up was carried out in 163 children, aged 6 months to 16 years, who were hospitalized because of acute, recurrent or chronic urticaria in 1976-1980. Etiologic agents were identified in 55% of cases. Physical factors were the commonest causes, especially in cases of chronic urticaria, while infections predominated in acute urticaria. 81% of the children participated in the follow-up study. Follow-up for a year or more revealed that 53% of the children had become symptom-free, 36% still had symptoms but less frequently and in 11% urticaria was unresolved. The results indicate that the etiologic factors in childhood urticaria are similar to those found in adults and that prognosis is favorable, particularly when the etiology is established.

Adolescent↗
PubMed1984

[Not Available].

Explore the source record for details and available documents.

Finland↗
PubMed1984

Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period.

A series of 446 inpatients with drug eruption was studied to determine the causative agent and the clinical type. In over a half of the cases a provocation test confirmed the drug responsible for the reaction. Sulphonamides/trimethoprim and ampicillin/penicillin followed by phenazones were the most frequent agents causing eruptions. Sulphonamides were also the most common drugs inducing Lyell's and Stevens-Johnson syndromes. Phenazones and barbiturates were the main causes of fixed eruptions. The frequency of inpatients having drug eruption was decreased in the 1971-80 series compared with the earlier one from 1961-70. Also the frequency of Lyell's and Stevens-Johnson syndromes was lower in the latter decade than in the earlier one.

Ampicillin↗
PubMed1983

Allergenic properties of a feed protein of microfungal origin.

We studied thirty-five process and laboratory workers occupationally exposed to Paecilomyces varioti protein. The protein, used as an animal feed, is prepared industrially by fermentation in pulp waste liquor. Skin tests and radioallergosorbent tests (RAST) to detect specific IgE antibodies showed positive results to Paecilomyces antigen among the workers and among the atopic control persons not occupationally exposed to Paecilomyces protein. Also IgG antibodies to Paecilomyces protein could be detected in workers and in controls in similar amounts in both groups. In no worker could clinical symptoms due to Paecilomyces protein allergy be found. We conclude that positive skin tests and RASTs indicate that immediate hypersensitivity to Paecilomyces antigens occurs. Clinical allergy probably has been prevented by the closed manufacturing process, which keeps occupational exposure at a low level.

Adult↗
PubMed1980

Aromatic plants--a cause of severe attacks of angio-edema and urticaria.

Celery and parsley were confirmed as etiological agents in 14 patients with severe attacks of angio-edema and urticaria. All of the patients proved to be atopic. Without exception they all had positive prick test reactions to mugwort. The patients were examined using the scratch - chamber test method and all of them showed positive reactions to celery and 12 patients to parsley. No peroral provocation tests were performed because of the severity of the reactions in the past. Passive transfer by the prausnitz-Küster technique was positive in two patients.

Adolescent↗
PubMed1976

Cutaneous reactions to practolol. Clinical and histopathological study.

In twelve patients with cutaneous reactions to practolol the clinical appearance of the rash was variable, including eczematous, exanthematous, lichenoid, and psoriasiform eruptions, and one exfoliative dermatitis. The development of the rash and its reappearance after oral challenge were slow. But histological findings were almost identical and were not those of any other drug eruption. Vacuolated and dyskeratotic epidermal cells and mild disorganization with extra mitoses of the epidermal cells were seen.

Administration, Oral↗