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Biomedical subjects

K Jonsson

Publications and source records attributed to K Jonsson.

At least 127 records · Page 7Linked to original sources

Analysis of complications after percutaneous transluminal angioplasty of renal artery stenoses.

During a five-year-period percutaneous transluminal renal angioplasty (PTRA) was attempted in 90 renal arteries with 109 stenoses and 3 occlusions in 78 patients. Complications were systematically recorded and classified as major, minor and radiological-technical. Twenty-one major complications (20.8%) including one fatality occurred as well as 17 minor, (16.8%) and 37 radiological-technical (36.6%) problems. The last group showed no clinical symptoms. The frequency of complications in our series is high compared with that in a survey of ten papers reviewing results in 675 patients. The most marked discrepancy was our high frequency of septic problems. Radiological changes are not usually reported in other series, probably because they are regarded as methodological but we considered these as potentially dangerous and important to report as they can lead to clinically relevant complications. Because of the problems reported here PTRA should only be performed in centres where complications can be properly dealt with.

Acute Kidney Injury↗

Synovial chondromatosis of the ankle.

Synovial chondromatosis is a rare disorder presenting a typical radiological appearance. We reviewed three patients with this disease in the ankle. Two of these patients were reexamined after 7 and 27 years, respectively. Although both had several calcified juxta-articular bodies in the ankle none of them had any clinical symptoms. This indicates that surgical intervention should be performed only if mechanical signs and symptoms are present.

Adult↗

Osteochondritis dissecans of the ankle. A 20-year follow-up study.

Thirty patients with osteochondritis dissecans of the ankle have been followed up for an average of 21 years. The histories and radiographs were reviewed, and it was found that most patients had only minor radiographic changes and symptoms. Two patients had developed osteoarthritis but in only one was this severe. Osteochondritis dissecans in the ankle thus seems to differ from the same lesion in the knee where late osteoarthritis often occurs. Two lesions were located on the joint surface of the distal tibia, a site not previously reported.

Adult↗

Complications after percutaneous transluminal angioplasty in the iliac, femoral, and popliteal arteries.

During a 5-year period percutaneous transluminal angioplasty (PTA) was attempted in 134 iliac, femoral, and popliteal arteries in 127 patients. Complications were systematically registered and classified as major, minor, and radiologic. Seventeen major complications (12.7%), including three deaths, occurred, as well as five minor (3.7%) and 13 radiologic complications (9.7%). The last group showed no clinical symptoms. The frequency of complications in our series is high compared with that found in a survey of 13 studies with 2043 patients. The most marked discrepancy was our high frequency of septic symptoms. A mortality rate of 2.2% was also higher in our series, but we have consequently registered the 30-day mortality rate to make comparisons with surgical series relevant. Radiologic alterations are usually not reported in other series probably because they are regarded as a part of the method, but we consider these alterations as potentially dangerous and important to report because they can result in clinically relevant complications. Because of the complications PTA should only be performed in centers in which complications can be optimally treated.

Adult↗

Treatment of arterial lesions after radiation therapy.

Of 1,724 patients who underwent peripheral vascular operation, 12 (0.7 per cent) underwent radiation therapy of the areas including the relevant arteries one and one-half to 28 years (a mean of 15 years) previously; one patient had carcinoma of the breast, three had tumors of the neck and eight patients had malignant gynecologic disease. One patient with an occluded carotid artery was not actively treated, two underwent percutaneous transluminal angioplasty and the remaining patients underwent different types of vascular reconstructions. These patients frequently have other radiation lesions as well with involvement of the skin, bladder or intestine, which may make them problematic from a surgical point of view. Extra-anatomic reconstructions or percutaneous transluminal angioplasty can be recommended. One patient died of malignant disease three years after arterial operation. Otherwise, the results of follow-up study for these patients did not differ from other patients who underwent arterial reconstruction.

Aged↗

Influence of selective mesenteric arteriography on the outcome of emergency surgery for massive, lower gastrointestinal hemorrhage. A 15-year experience.

From 1970 to 1984, 64 patients with massive hemorrhage of lower gastrointestinal origin were treated at the intensive care unit, Surgical Department, Malmö General Hospital. The records of these patients have been studied retrospectively. Emergency exploration for hemostasis was performed on 31 patients, while in 33 patients hemorrhage stopped with conservative therapy. Acute selective mesenteric arteriography revealed the bleeding site in 16 of 28 patients (57 percent). The commonest bleeding sources detected by selective mesenteric arteriography were diverticular disease and angiodysplastic lesions of the colon. Fourteen patients with positive arteriography finding were operated on as emergencies, resulting in two postoperative deaths. Ten patients were operated on as emergencies without preoperative arteriography. Despite intraoperative efforts, no bleeding source was found in three of those patients. In the remaining seven patients, the diagnoses were similar to the 14 patients with positive arteriography. Five of 10 patients in this group died postoperatively. Emergency laparotomy eventually was necessary in seven of 12 patients with negative arteriography. This group had a variety of diagnoses and no postoperative mortality. Positive preoperative mesenteric arteriography findings allowed the surgeon to perform a limited resection of the bleeding bowel segment with a reduced postoperative mortality.

Adolescent↗

Wrist denervation and compression of the lunate in Kienböck's disease.

Thirteen wrists with Kienböck's disease, stage III or IV, were denervated. Three wrists were examined repeatedly over a period of 2 1/2 years prior to operation, showing the natural course of lunate compression. The remaining 10 wrists were operated on sooner after diagnosis and the lunate compression was compared with the natural compression course. The hypothesis that wrist denervation was detrimental to the lunate was not supported by the present material.

Adolescent↗

Late results in 65 physeal ankle fractures.

Fifty-nine Salter-Harris III and IV lesions of the medial malleolus, Tillaux fractures, and triplane fractures were examined after 9 (3-32) years to assess the frequency of late symptoms, deformity, joint incongruity, and secondary arthrosis. Six out of 18 Salter-Harris III and IV lesions of the medial malleolus were reduced open, none of which had any signs of growth disturbance, whereas 1 case, left with a 3-mm residual dislocation, had 5 degrees of anterior angulation. Of the 17 Tillaux fractures, ten were not reduced and two of these gave slight symptoms, whereas five openly reduced fractures were asymptomatic at follow-up. Out of 18 triplane fractures, not reduced, two gave slight ankle pain and another had 6 degrees of anterior angulation, whereas three of ten reduced fractures were symptomatic. The overall results were good and no case of arthrosis, defined as reduction of the joint space, was found in any of the fracture groups despite a follow-up of 12 or more years in one third of the cases.

Adolescent↗

Myelography in the elderly and the diagnosis of spinal stenosis.

To evaluate the width of the spinal canal when diagnosing spinal stenosis, 91 patients older than 59 years of age when undergoing myelography were studied. Using a sagittal diameter of 11 mm as border for the diagnosis of spinal stenosis, it was found that 31 of the 66 patients with spinal claudication, suspicion of spinal claudication and sciatic pain fulfilled this criterion and that 3/25 of the control group and those with atypic symptoms had a sagittal diameter of 11 mm or less. Five patients showed a complete block on the myelogram, and all of them had a typical spinal claudication. The spinal canal will narrow with age in asymptomatic patients as well, and the myelographic stenosis in elderly patients is not always equivalent to a clinical diagnosis of spinal stenosis.

Aged↗

Piroxicam in the treatment of primary dysmenorrhea.

In double-blind, crossover studies, piroxicam was compared with naproxen sodium and with placebo. The different parameters studied were pain intensity, patient's opinion of the drugs tested, complementary pharmacological treatment, ability to work, overall effect, treatment preference, and side effects. It was concluded that piroxicam was comparable to naproxen sodium and that piroxicam was significantly better than placebo, as regards these parameters. It was also concluded that piroxicam has an effect equivalent to that of naproxen sodium, an accepted treatment for dysmenorrhea.

Adolescent↗

Long-term follow-up in chronic non-obstructive pyelonephritis. A retrospective radiological study.

Chronic non-obstructive pyelonephritis has been followed for periods ranging from 18 to 40 years (mean 25), by using series of urographies and clinical examinations. The patients studied were fifteen adults, and eight children who were between the ages of three months and eleven years at their initial examinations. Among the adults, progressive scarring was found in 3 patients with renal calculi, the others remaining unchanged during the follow-up period. Among the children, progressive scarring was found in all affected kidneys, the scarring progressing during early childhood and adolescence, and then remaining unchanged during adult life. This retrospective study indicates that calyceal clubbing and parenchyma scarring occur during childhood and seldom progress without the intrusion of superimposing factors, such as renal stone formation.

Adolescent↗

Silicone carpal implants: risk or benefit?

The present report is based on assessment of 48 patients who underwent carpal Silastic H.P. implant arthroplasty (trapezium, condylar, scaphoid, lunate and scapholunate implants). Mean follow-up period was 29 months (range 6-82). Recurrent pain and/or evidence of wrist synovitis and lytic lesions made early subsequent surgery necessary in 10 patients. In the remaining 38 patients the post-operative course was followed for an average period of 33 months (range 8-82). Severe giant-cell silicone synovitis combined with isolated or disseminated osteolytic lesions were found in 17/30 (56%) patients with scaphoid or lunate implants and in 2/18 (11%) with other types of Silastic carpal implants. Well-defined cysts were observed within 8 months of insertion of the implant. Morphologically, an erosive giant-cell synovitis was regularly seen, with large quantities of intra- and extracellular silicone debris. Abraded material was also observed in central parts of normal bone and in lymph node tissue distant from the implant. The ultimate tissue response to this propagation of silicone particles is unknown. The situation is of great concern and the continued use of proximal carpal Silastic H.P. implants should at present be seriously questioned.

Adolescent↗

Thirty-year follow-up of ankle fractures.

The natural course of ankle fractures was studied in 143 patients treated by closed methods. The average time elapsing from fracture to follow-up was 29 years. Eighty-two per cent had no radiographic signs of arthrosis; 83 per cent were free of symptoms. The most common fracture, supination eversion Stage II (49 cases), gave rise to minimal signs of arthrosis in only one patient, who had moderate symptoms. The suggestion that all ankle fractures must be perfectly reduced is not supported by the findings of the present study.

Adult↗