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Biomedical subjects

K J Olsen

Publications and source records attributed to K J Olsen.

43 records · Page 3Linked to original sources

Relation between severity of thyrotoxicosis and response to 131I therapy.

The relation between the severity of hyperthyroidism and response to 131I therapy was tested in a group of 45 patients 6 to 12 months after therapy. At following treatment 7 patients were hypothyroid, 13 euthyroid and 25 hyperthyroid. The absolute iodine uptake and gland size was significantly higher in the hyperthyroid group compared with the other groups. The radiation dose was similar in the groups, but the ratio between dose and uptake was significantly lower in the hyperthyroid group.

Adult↗

Separation of labelled iodide, iodoprotein, iodotyrosines, and iodothronines in serum from patients treated with iodine-131, using an improved chromatographic method.

A method is described for complete separation of iodoprotein, 3-iodotyrosine (MIT), 3,5-diiodotyrosine (DIT), 3,5,3-triiodo-L-thyronine (T3), and L-throxine (T4) on a single column run on Sephadex G-25 superfine in alkaline solution. Sera from patients treated with 131I- have been analysed by this method after removal of I- by resin dialysis.

Chromatography, Gel↗

Relations of bone mineral content, ash weight and bone mass: implication for correction of bone mineral content for bone size.

Bone mineral content (BMC) was measured by photon absorptiometry in fresh bone specimens: 35 iliac crest and 39 forearms were used. BMC was related to ash weight, fat-free weight and the amount of bone determined by quantitative histologic methods. Ninety-five per cent of the variation in bone mineral concentration (BMC') in the iliac crest could be explained by variation in ash weight, and 88% of the variation in BMC in the forearm could be explained by variation in the amount of bone determined histologically. The total cross-sectional bone area of radius and ulna could be calculated from the width of the structures measured on the photon absorption curves. Using this parameter and the relation between BMC and ash weight, the actual in-vivo bone mineral content in the forearm could be expressed in terms of ash-weight in grams per cm3 of total bone.

Anthropometry↗