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Biomedical subjects

K Honda

Publications and source records attributed to K Honda.

871 records · Page 49Linked to original sources

The double balloon cannula in the treatment of ruptured abdominal aneurysms.

Two cases of ruptured abdominal aneurysm were successfully treated, using the double balloon cannula, which was devised in our surgical department. After cross-clamping of the descending thoracic aorta and both common iliac arteries, a small incision was made in the aneurysm and the cannula was inserted through this incision into the lumen of the abdominal aorta and positioned at the proximal end of the aneurysm. Then the double balloon was inflated, blocking the blood flow just above the aneurysm. The aneurysm was incised, and grafting was performed, in the usual manner, in a bloodless surgical field. The double balloon cannula was beneficial not only in preventing massive blood loss during surgery, but also in maintaining the blood supply to various abdominal organs.

Aorta, Abdominal↗

Long-term results of omental transplantation for chronic occlusive arterial diseases.

Twenty cases of thromboangitis obliterans (21 limbs) and five cases of atherosclerosis obliterans (five limbs) were treated with omental transplantation. Angiographic findings in these patients showed poor distal run-off, and direct reconstructive surgery was not indicated. Follow-up studies were conducted for an average of five years and one month (3 mos to 9 yrs. and 8 mos.). The long-term follow-up of 19 cases with thromboangitis obliterans (TAO) (20 limbs) revealed excellent results in 62%, good results in 19% and poor results in 19%. The results of the five cases with atherosclerosis obliterans (ASO) (5 limbs) were good in 20% and poor in 80%. Long-term results of omental transplantation show it to be remarkably effective in treating TAO but not ASO.

Adult↗

Extracorporeal circulation with perfluorochemicals (Fluosol-DA).

Experimental studies on extracorporeal circulation (ECC) with perfluorochemicals (Fluosol-DA) as a perfusate was performed to examine oxygen carrying capacity and its organ distribution using eight calves. Approximately 80% of the circulating blood volume was withdrawn before ECC and reinfused after completion of ECC. ECC time was 60 minutes in five of the calves and 120 minutes in three of the calves. Hct and Hb decreased to 4-12% and 1.7-6.6 g/dl during ECC. Fct (Fluorocrit: volume percentage of Fluosol-DA) ranged between 5 and 10%. PaO2 and PvO2 were 432-543 mmHg and 93-164 mmHg. Sixty-seven to 86% of the oxygen consumed by the tissues was delivered by Fluosol-DA. One of the complications of ECC with Fluosol-DA, hemolysis was observed in four of the calves which had a relatively high level of Fluosol-DA retention (13.9 g/kg) in the body after ECC. The retention volume of the other four calves which did not show hemolysis was 10.0 g/kg. Retention of Fluosol-DA after ECC was found to be greater in the reticuloendothelial system of the calves sacrificed earlier and became trace or minimal after 10 months.

Alanine Transaminase↗

Radiotherapy of T1 and T2 glottic cancer: analysis of anterior commissure involvement.

From January 1984 to December 1993, 184 patients with previously untreated T1 and T2 (UICC 1987) laryngeal glottic cancer underwent radiotherapy at Hyogo Medical Center for Adults. The prognostic variables analyzed included sex, age, smoking index, T stage, tumor size, tumor type, gross anterior commissure involvement (gross ACI), histological differentiation, administered dose, TDF, overall treatment time, chemotherapy, initial response, and the dose required to achieve CR. Both univariate and multivariate analyses were performed. The T stage, tumor size, and gross ACI were significant variables in univariate analysis, while the tumor type and gross ACI were significant on multivariate analysis. The 5-year recurrence-free survival of patients with gross ACI was significantly worse than that of those without ACI (57.6% vs. 89.9%). Among gross ACI patients, the recurrence-free survival of those treated with 70-72 Gy was superior to that of those receiving 60-62 Gy, suggesting that at least 70 Gy was necessary to control such diseases.

Adult↗