Search PubMed⌕ Search

Biomedical subjects

K Hisada

Publications and source records attributed to K Hisada.

At least 343 records · Page 19Linked to original sources
PubMed1981

Subcellular distribution of 111In and 169Yb in tumor and liver.

Subcellular distribution of 111In and 169Yb was quantitatively determined to evaluate the role of the lysosome in the accumulation of these nuclides in malignant tumor tissue and in the liver using three different tumor models and the host liver. In Yoshida sarcoma and Ehrlich tumor, most of the radioactivity of these nuclides was localized in the supernatant fraction, and only a small amount of radioactivity was localized in the mitochondrial fraction, which contains lysosomes. In the liver, most of the radioactivity was concentrated in the mitochondrial fraction. The radioactivity of this fraction increased with time after the administration of these nuclides and reached approximately 50% of the total radioactivity within 24 h. In the case of hepatoma AH109A, radioactivity of the mitochondrial fraction increased with time after administration, and about 30% of the total radioactivity was concentrated in this fraction after 24 h. It is concluded that the lysosome does not play a major role in the tumor concentration of these nuclides, although it may play an important role in their liver concentration. In the case of hepatoma AH109A, it is presumed that lysosome plays a considerably important role in the tumor concentration of these nuclides, hepatoma AH109A possessing some residual features of the liver.

Animals↗
PubMed1981

Three types of abnormal scan patterns in posterior cerebral artery infarction.

It has been reported that the tentorial confluence sign and/or hockey stick pattern on static imaging are useful in evaluating posterior cerebral artery (PCA) infarctions. In 16 cases with PCA infarction, the tentorial confluence sign was found in all cases, but a hockey stick pattern was seen in only half of these patients. The abnormal accumulations may be classified into three types. These three types seem to be consistent with the territory of the blood supply from the cortical, temporal, and/or occipital branches of the posterior cerebral artery. Emission computed tomography images may also demonstrate this consistency.

Adolescent↗
PubMed1981

Diffusely increased Tc-99m-MDP uptake in both kidneys.

Patients with diffusely increased uptake in both kidneys (often referred to as "host kidneys") on Tc-99m-MDP bone imaging were evaluated. Among 2056 patients reviewed, this finding was seen in 13 patients (0.63%): four with liver cirrhosis, two with lung cancer, one each with primary hepatoma, Hodgkin's disease, malignant lymphoma, thyroid cancer, leukemia, sideroblastic anemia and diabetes mellitus. Renal vascular disease and iron overload are considered to be the major causes of this finding.

Adult↗
PubMed1981

Assessment of cardiac wall motion with the ejection fraction image: a comparison with contrast left ventriculography.

Twenty patients with ischemic heart disease were studied with biplane contrast left ventriculography and gated bloob pool scans. An ejection fraction (EF) image was calculated from each gated blood pool scan. The EF image and contrast ventriculograms were divided into three regions and seven segments respectively. The sites of asynergy observed in each study were compared. Segments two, three and six of the contrast ventriculogram corresponded to the anteroseptal and inferoapical regions of the EF image, but it was difficult to differentiate between these segments on the EF image. Segments three and four corresponded to the inferoapical region and segments five and seven corresponded to the posterolateral region. Diffuse asynergy with a low EF (less than 30%) causes a large defect on the EF image. The mean regional EF obtained from the EF image correlated well with the EF calculated from the left ventricular volume curve (n = 50, r = 0.94).

Angiocardiography↗
PubMed1981

Visualization of hypertrophied papillary muscle mimicking left ventricular mass on gated blood pool and T1-201 myocardial perfusion imaging.

A sixty-year old man with acute myocardial infarction was incidentally found to have a hypertrophied anterolateral papillary muscle (ALPPM) of the left ventricle on gated blood pool (GBP) and T1-201 myocardial perfusion images. Hypertrophy of the ALPPM was visualized as a movable defect in the lateral basal area on GBP imaging throughout the cardiac cycle and on the TI-201 study as a radionuclide accumulating structure, consistent with the defect in the GBP. A combination of these findings may suggest the presence of a hypertrophied papillary muscle of the left ventricle.

Cardiomyopathies↗
PubMed1981

Three-dimensional regional cerebral blood perfusion images with single-photon emission computed tomography.

Twenty-seven patients were studied for cerebral blood perfusion abnormalities using krypton 81m. A solution of 81mKr was continuously infused into an internal carotid artery, and single-photon emission computed tomograms were recorded. The transverse section images using 81mKr represented the three-dimensional regional cerebral blood perfusion, and this technique seemed to be useful for evaluating the regional cerebral blood perfusion in the deep brain.

Cerebrovascular Circulation↗
PubMed1981

[Measurement volume of intracranial hematoma by computed tomography (author's transl)].

On hypertensive intracranial hematoma, the hematoma volume on CT scan was measured by Delta scan 50 with MAP-program. 1) In each slice of the hematoma, high density mass lesion, the area was measured by joy stick on viewing console, and relationship with print out data, area above 40 CT values was good. 2) Correction of partial volume effect, especially of high of hematoma in the 10 mm scan slice was done with each mean CT values of the hematoma, and central CT values of that. For correction of partial volume effect, hematoma volume was decreased compared with the volume measured by MAP area measurement only, but in phantom study, corrective hematoma volume has shown high accuracy. 3) In comparison of corrective hematoma volume with maximum length of hematoma, line measurement does not evaluate of hematoma volume proportionaly as large. Though calculated volume by modified Dodge's formula (pi/6 X L X S X slice) has shown good relationship with corrective hematoma volume. Then, in clinical use, measurement of 3 line distance, maximum length, crossed short length, slice thickness contained hematoma was recommended to evaluate actual hematoma volume.

Cerebral Hemorrhage↗